Articles & Issues

As medical care has advanced, the ability to resuscitate infants with gestational ages of 23-30 weeks and birth weight 400-1000 g has improved. However, outcomes for infants in this category are quite...

Chest pain is a common and sometimes vexing complaint in children and adolescents. It is well-recognized that most chest pain in the pediatric population is unrelated to heart disease, but does this m...

Over the years, multiple interventions have been used to treat apnea of prematurity – ranging from increased oxygen exposures to physical stimulation to pharmacologic interventions. The group in Winni...

This issue of The Journal includes two articles that examine the use of fresh frozen plasma (FFP). At first glance, the authors appear to have differing views as to the benefits and overall utilizatio...

In this issue of The Journal, von Kries et al have addressed one of the more controversial questions in the care of pediatric orthopedic patients. Many have attempted to balance the value of early det...

It has been almost 20 years since proton pump inhibitors (PPIs) were initially shown to be effective, safe, and well-tolerated for the short-term treatment of gastroesophageal reflux disease (GERD) in...

The history of calciferol∗ metabolism and biochemistry is tightly intertwined with that of American pediatrics. Rickets was a widespread affliction of children in urban areas in the 19th and early 20t...

Objective: To evaluate coagulopathy in pediatric trauma patients on presentation to the emergency department, and to quantify the relationship with mortality. Study design: Pediatric trauma patients r...

Objective: To explore the commonly recorded diagnoses in overweight and obese children presenting to a clinical care setting compared with their normal-weight peers. Study design: This was a cross-sec...

Objectives: To evaluate whether the use of adult heart rate (HR) criteria is appropriate for diagnosing orthostatic intolerance (OI) and postural tachycardia syndrome (POTS) in children and adolescent...

Objective: To assess home oxygen use in preterm infants, identify risk factors predicting home oxygen use, and quantify the extent of institutional variation in home oxygen use across neonatal intensi...

Objective: To measure the circulating concentrations of nitric oxide (NO) adducts with NO bioactivity after inhaled NO (iNO) therapy in infants with pulmonary hypertension. Study design: In this singl...

Objective: To determine whether ibuprofen displaces bilirubin from albumin in preterm infants. Study design: A total of 34 preterm neonates (<32 weeks gestation) treated by ibuprofen (10-5-5 mg/kg)...

Objectives: To assess the effectiveness of general ultrasound screening to prevent first operative procedures of the hip. Study design: We conducted a case-control study in a population in which gener...

Steffey JM. J Pediatr 1962;60:183-90

Objective: To identify factors associated with frequent severe vaso-occlusive pain crises in a contemporary pediatric cohort of patients with sickle cell anemia (SCA) enrolled in a prospective study o...

Objective: To evaluate relationships among vitamin D, proteinuria, and disease activity in pediatric systemic lupus erythematosus (SLE) and juvenile dermatomyositis (JDM). Study design: Multiple linea...

Objective: To assess the interrelationship between extent of adrenarche at presentation in girls with precocious adrenarche (PA) born appropriate for gestational age and their growth pattern, pubertal...

Objective: To examine the prevalence of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition psychiatric disorders in youth with chest pain compared with a control sample with innocen...

Objective: To examine physical and mental health functioning among Asian-American children of US-born and immigrant parents. Study design: We used data from the Early Childhood Longitudinal Study-Kind...

Two preterm infants with athetoid cerebral palsy due to bilirubin encephalopathy were examined by magnetic resonance spectroscopic imaging at age 3 years. An increased glutamate/glutamine complex/crea...

Hypoparathyroidism-retardation-dysmorphism (HRD) syndrome (OMIM 241410), also known as Sanjad-Sakati syndrome, is a rare autosomal recessive disorder characterized by hypoparathyroidism, growth failur...

A term-born baby girl had a perinatal course complicated by meconium aspiration syndrome, pulmonary hemorrhage, and shock. She was placed on extracorporeal membrane oxygenation (ECMO) on day of life 3...

Primary tumors of the liver account for approximately 1% of malignancies in children, with an annual incidence of 1.6 cases per million children in the United States. Between 50% and 60% of hepatic tu...

A healthy 9-month-old girl playing with her father’s cufflink suddenly developed respiratory distress, coughing, and inconsolable crying. The child’s mother attempted to search her mouth using a blind...

Like nearly all previous authors, Morgan et al report that patients with transfusion-related acute gut injury (TRAGI) are of lower birth weight and gestational age and develop disease later in life co...

We thank Regelmann et al for sharing our interest in this subject and posing important clinical research questions related to medication-induced diabetes mellitus. We acknowledge the heterogeneity of ...