| The Editors' Perspectives |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Specificity of cytokine abnormalities in HLH
Hemophagocytic lymphohistiocytosis (HLH) is both under-recognized and over-diagnosed currently. Despite the use of the revised criteria for diagnosis, established by the Histiocyte Society in 2004, it...
|
Sarah S. Long
|
A1
|
|
|
|
Breastfeeding protects against asthma in children
Silvers et al from the University of Otago in New Zealand recently completed a study on the effects of breastfeeding on wheezing and current asthma in children aged 2 to 6 years. This was a large stud...
|
Robert W. Wilmott
|
A1
|
|
|
|
Imaging studies for evaluation of acute appendicitis in children
Bachur et al performed a retrospective study of utilization of imaging and outcomes in children evaluated in Emergency Departments for acute appendicitis using an administrative database that included...
|
Sarah S. Long
|
A2
|
|
|
|
Capnography to detect endotracheal tube dislodgement
Pediatric residents were trained in intubation and resuscitation in a simulation lab at Yale University, and a randomized control study was performed to see whether standard monitoring plus capnograph...
|
Robert W. Wilmott
|
A2
|
|
|
|
Iron and hepcidin in the preterm
Iron metabolism is problematic in the very preterm infant because of low iron stores at birth and the multiple effects of inflammation, blood loss for testing, nutritional deficits, and transfusion. T...
|
Alan H. Jobe
|
A2
|
|
|
|
Obesity treatment: putting guidelines to work
There has been substantial research on the treatment of obesity in children and adolescents. These results have been incorporated in the American Medical Association/Centers for Disease Control and Pr...
|
Stephen R. Daniels
|
A2-A3
|
|
|
|
Lead and growth: when, not just how much
A number of studies have suggested that one of the non-cognitive effects of childhood lead exposure is growth retardation. Many environmental toxins have specific “windows” of time in which exposure i...
|
Thomas R. Welch
|
A3
|
|
|
|
Table of Contents
|
|
A4-A7
|
|
|
|
Masthead
|
|
A8
|
|
|
|
Information for Readers
|
|
A9
|
|
| Notes from the Association of Medical School Pediatric Department Chairs, Inc. |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Getting Past Getting By: Training Culturally and Linguistically Competent Bilingual Physicians
Effective health care depends on clear communication. It follows that effective health care education must emphasize physicians' communication skills. For the growing number of limited English-profici...
|
John D. Cowden,
Darcy A. Thompson,
Jennifer Ellzey,
Michael Artman
|
891-892.e1
|
|
| Editorials |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Diabetes Mellitus and Growth in Children and Adolescents
24 February 2012
Before the isolation of insulin in 1923, growth failure and eventual death from starvation were predictable in children with type 1 diabetes mellitus (T1DM), because nutritional therapy was inadequate...
|
Tamara S. Hannon,
Alan D. Rogol
|
893-894
|
|
|
|
β-Cell Dysfunction and the Onset of Type 2 Diabetes
01 March 2012
The pathophysiology of type 2 diabetes has been elegantly described in the adult, with both insulin resistance and β-cell dysfunction identified as contributors to diabetes onset. Which of these abnor...
|
Ilene Fennoy
|
895-896
|
|
|
|
Preventive Nephrology: A Role for the Pediatrician
09 March 2012
It is now more than 20 years ago since David Barker proposed that many chronic adult diseases originate from compromised fetal and early postnatal development. Barker’s proposal was mainly based on ep...
|
Anita Aperia
|
896-897
|
|
| Commentary |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Obesity and Neglect: It's about the Child
16 April 2012
Recently, controversy has arisen when a proposal for (and subsequent report of) state intervention to protect a child from life-threatening consequences of obesity was countered by assertions that rem...
|
David B. Allen,
Norman Fost
|
898-899
|
|
| Original Articles |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Growth in Children and Adolescents with Type 1 Diabetes
13 January 2012
Objective: To investigate the effect of type 1 diabetes on growth and adult height. Study design: Data from 22 651 children (10 494 females) with type 1 diabetes documented at onset of the disease fro...
|
Walter Bonfig,
Thomas Kapellen,
Axel Dost,
Maria Fritsch,
Tilman Rohrer,
Johannes Wolf,
Reinhard W. Holl,
Diabetes Patienten Verlaufsdokumentationssystem Initiative of the German Working Group for Pediatric Diabetology and the German Bundesministerium für Bildung und Forschung Competence Net for Diabetes Mellitus
et al.
|
900-903.e2
|
|
|
|
β-Cell Dysfunction in Adolescents and Adults with Newly Diagnosed Type 2 Diabetes Mellitus
12 January 2012
Objective: To compare β-cell function in adolescents and adults with newly diagnosed type 2 diabetes (T2DM). Study design: Thirty-nine adolescents with T2DM, 38 age- and weight-matched control subject...
|
Deborah A. Elder,
Patricia M. Herbers,
Tammy Weis,
Debra Standiford,
Jessica G. Woo,
David A. D’Alessio
et al.
|
904-910
|
|
|
|
Health-Related Quality of Life in Adolescents with or at Risk for Type 2 Diabetes Mellitus
05 January 2012
Objective: To evaluate how adolescents with or at risk for type 2 diabetes mellitus (T2DM) and their parent/guardians (parents) perceive adolescents’ health-related quality of life. Study design: We i...
|
Erinn T. Rhodes,
Michael I. Goran,
Tracy A. Lieu,
Robert H. Lustig,
Lisa A. Prosser,
Thomas J. Songer,
Marc J. Weigensberg,
Ruth S. Weinstock,
Tessa Gonzalez,
Kaitlin Rawluk,
Roula M. Zoghbi,
David S. Ludwig,
Lori M. Laffel
et al.
|
911-917
|
|
|
|
Implementation of Clinical Practice Guidelines for Pediatric Weight Management
12 January 2012
Objective: To evaluate the effect of computer-assisted decision tools that standardize pediatric weight management in a large, integrated health care system for the diagnosis and management of child a...
|
Karen J. Coleman,
Anne C. Hsii,
Corinna Koebnick,
Ana F. Alpern,
Brenna Bley,
Marianne Yousef,
Erin M. Shih,
Keila J. Trimble-Cox,
Ning Smith,
Amy H. Porter,
Steven D. Woods
et al.
|
918-922.e1
|
|
|
|
Increased Albuminuria in 4-Year-Old Preterm-Born Children with Normal Height
19 January 2012
Objective: To determine risk factors for high blood pressure (BP), increased markers of glomerulosclerosis, and tubular dysfunction in 4-year-old preterm-born children. Study design: The study group w...
|
Rachel Vieux,
Jean-Michel Hascoët,
Patricia Franck,
F. Guillemin
|
923-928.e1
|
|
|
|
Timing of Patent Ductus Arteriosus Treatment and Respiratory Outcome in Premature Infants: A Double-Blind Randomized Controlled Trial
30 January 2012
Objective: To determine whether “early” ibuprofen treatment, at the onset of subtle patent ductus arteriosus (PDA) symptoms, would improve respiratory outcome in premature infants compared with “expec...
|
Ilene R.S. Sosenko,
M. Florencia Fajardo,
Nelson Claure,
Eduardo Bancalari
|
929-935.e1
|
|
|
|
Cerebral Autoregulation in Neonates with a Hemodynamically Significant Patent Ductus Arteriosus
09 January 2012
Objective: Very low birth weight (VLBW) preterm infants are at risk for impaired cerebral autoregulation with pressure passive blood flow. Fluctuations in cerebral perfusion may occur in infants with ...
|
Valerie Y. Chock,
Chandra Ramamoorthy,
Krisa P. Van Meurs
|
936-942
|
|
|
|
Transitional Changes in Cardiac and Cerebral Hemodynamics in Term Neonates at Birth
13 January 2012
Objective: To describe cardiac function, cerebral regional oxygen saturation (rSO2), and cerebral blood flow (CBF) that correspond to changes in arterial oxygen saturation (SaO2) in normal term neonat...
|
Shahab Noori,
Anne Wlodaver,
Venugopal Gottipati,
Michael McCoy,
Daniel Schultz,
Marilyn Escobedo
et al.
|
943-948
|
|
|
|
Hepcidin Concentrations in Serum and Urine Correlate with Iron Homeostasis in Preterm Infants
30 January 2012
Objectives: To evaluate whether hepcidin concentrations in serum (Hep(S)) and urine (Hep(U)) correlate with iron metabolism, erythropoiesis, and inflammation in preterm infants. Study design: Thirty-o...
|
Katharina F. Müller,
Laila Lorenz,
Christian F. Poets,
Mark Westerman,
Axel R. Franz
et al.
|
949-953.e2
|
|
|
|
Vitamin A Supplementation Improves Retinal Function in Infants at Risk of Retinopathy of Prematurity
30 January 2012
Objective: Preterm infants show reduced retinal sensitivity at term corrected age compared with newborn term infants. We tested the hypothesis that retinal sensitivity in preterm infants is improved b...
|
Helen Mactier,
Daphne L. McCulloch,
Ruth Hamilton,
Peter Galloway,
Michael S. Bradnam,
David Young,
Timothy Lavy,
Lesley Farrell,
Lawrence T. Weaver
et al.
|
954-959.e1
|
|
|
|
Clinical Sepsis in Neonates and Young Infants, United States, 1988-2006
19 January 2012
Objective: To describe the burden and characteristics of clinical neonatal sepsis in the United States and evaluate incidence rates after the issuance of intrapartum antibiotic prophylaxis (IAP) guide...
|
Susan L. Lukacs,
Stephanie J. Schrag
|
960-965.e1
|
|
|
|
Effect of Ethnicity and Race on Cognitive and Language Testing at Age 18-22 Months in Extremely Preterm Infants
24 January 2012
Objective: To evaluate the relationship of race/ethnicity to Cognitive and Language scores on the Bayley Scales of Infant and Toddler Development, Third Edition in extremely preterm toddlers (<28 +...
|
Andrea Freeman Duncan,
Kristi L. Watterberg,
Tracy L. Nolen,
Betty R. Vohr,
Ira Adams-Chapman,
Abhik Das,
Jean Lowe,
Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
et al.
|
966-971.e2
|
|
|
|
An Evidence-Based Catheter Bundle Alters Central Venous Catheter Strategy in Newborn Infants
12 January 2012
Objective: To assess whether introduction of an evidence-based percutaneously inserted central catheter (PICC) care bundle reduced the risk of central line-associated bloodstream infection (CLABSI), t...
|
Meggan Butler-O’Hara,
Carl T. D’Angio,
Hyacinth Hoey,
Timothy P. Stevens
|
972-977.e2
|
|
|
|
Cancer in Children with Nonchromosomal Birth Defects
13 January 2012
Objective: To examine whether the incidence of childhood cancer is elevated in children with birth defects but no chromosomal anomalies. Study design: We examined cancer risk in a population-based coh...
|
Paul Graham Fisher,
Peggy Reynolds,
Julie Von Behren,
Suzan L. Carmichael,
Sonja A. Rasmussen,
Gary M. Shaw
et al.
|
978-983
|
|
|
|
Diagnostic Accuracy of a Specific Cytokine Pattern in Hemophagocytic Lymphohistiocytosis in Children
09 January 2012
Objective: The study goal was to determine the diagnostic accuracy of a specific cytokine pattern including interferon-gamma (IFN-γ), interleukin (IL)-10, and IL-6 for hemophagocytic lymphohistiocytos...
|
Xiao-Jun Xu,
Yong-Min Tang,
Hua Song,
Shi-Long Yang,
Wei-Qun Xu,
Ning Zhao,
Shu-Wen Shi,
He-Ping Shen,
Jun-Qing Mao,
Ling-Yan Zhang,
Bin-Hua Pan
et al.
|
984-990.e1
|
|
|
|
Breastfeeding Protects against Current Asthma up to 6 Years of Age
30 January 2012
Objective: To investigate the effects of breastfeeding on wheezing and current asthma in children 2 to 6 years of age. Study design: Infants (n=1105) were enrolled in a prospective birth cohort in New...
|
Karen M. Silvers,
Chris M. Frampton,
Kristin Wickens,
Philip K. Pattemore,
Tristram Ingham,
David Fishwick,
Julian Crane,
G. Ian Town,
Michael J. Epton,
New Zealand Asthma and Allergy Cohort Study Group
et al.
|
991-996.e1
|
|
|
|
Use of Technology with Health Care Providers: Perspectives from Urban Youth
16 January 2012
Objective: To evaluate urban youths’ use of and access to technology and solicit their opinions about using technology with healthcare providers. Study design: Urban youth (aged 14-24 years) were invi...
|
Sarah Lindstrom Johnson,
S. Darius Tandon,
Maria Trent,
Vanya Jones,
Tina L. Cheng
et al.
|
997-1002
|
|
|
|
50 Years Ago in The Journal of Pediatrics: Mother-Baby Oxygen Gradients
Graham BD. J Pediatric 1962;60:882-8
|
Clyde J. Wright
|
1002
|
|
|
|
Influence of Race and Socioeconomic Status on the Diagnosis of Child Abuse: A Randomized Study
05 January 2012
Objectives: To measure empirically the influence of race and socioeconomic status (SES) on the diagnosis of child abuse and willingness to report to child protection services. Study design: A total of...
|
Antoinette L. Laskey,
Timothy E. Stump,
Susan M. Perkins,
Gregory D. Zimet,
Steven J. Sherman,
Stephen M. Downs
et al.
|
1003-1008.e1
|
|
|
|
Improving Detection by Pediatric Residents of Endotracheal Tube Dislodgement with Capnography: A Randomized Controlled Trial
13 January 2012
Objective: The authors sought to determine if capnography could improve time to correction of a simulated endotracheal tube (ETT) dislodgement by pediatric residents. Study design: Pediatric residents...
|
Melissa L. Langhan,
Marc Auerbach,
Alla N. Smith,
Lei Chen
|
1009-1014.e1
|
|
|
|
Incidence of Febrile Urinary Tract Infections in Children after Successful Endoscopic Treatment of Vesicoureteral Reflux: A Long-Term Follow-Up
30 January 2012
Objective: To evaluate the incidence of febrile urinary tract infection (UTI) after successful endoscopic correction of intermediate and high-grade vesicoureteral reflux (VUR). Study design: Medical r...
|
Manuela Hunziker,
Nochiparambil Mohanan,
Federica D’Asta,
Prem Puri
|
1015-1020
|
|
|
|
Gastrointestinal Bleeding in Infantile Hemangioma: A Complication of Segmental, Rather than Multifocal, Infantile Hemangiomas
12 January 2012
Objective: To highlight an association of facial segmental hemangiomas with gastrointestinal bleeding in infants with infantile hemangiomas. Study design: We conducted a multicenter retrospective case...
|
Beth A. Drolet,
Elena Pope,
Anna M. Juern,
Thomas Sato,
Brandon Howell,
Katherine Brown Puttgen,
Irene Lara-Corrales,
Amy Gilliam,
Anthony Mancini,
Julie Powell,
Dawn Siegel,
Denise Metry,
David A. Stevenson,
Johannes F. Grimmer,
Ilona J. Frieden
et al.
|
1021-1026.e3
|
|
|
|
Iron Deficiency in Infancy is Associated with Altered Neural Correlates of Recognition Memory at 10 Years
13 January 2012
Objective: To determine the long-term effects of iron deficiency on the neural correlates of recognition memory. Study design: Non-anemic control participants (n=93) and 116 otherwise healthy formerly...
|
Eliza L. Congdon,
Alissa Westerlund,
Cecilia R. Algarin,
Patricio D. Peirano,
Matthew Gregas,
Betsy Lozoff,
Charles A. Nelson
et al.
|
1027-1033
|
|
|
|
Advanced Radiologic Imaging for Pediatric Appendicitis, 2005-2009: Trends and Outcomes
22 December 2011
Objectives: To examine the variability in the use of computed tomography (CT) and ultrasound (US) for children with appendicitis and identify associations with clinical outcomes, and to demonstrate an...
|
Richard G. Bachur,
Kara Hennelly,
Michael J. Callahan,
Michael C. Monuteaux
|
1034-1038
|
|
|
|
Utility of Contrast Echocardiography for Pulmonary Arteriovenous Malformation Screening in Pediatric Hereditary Hemorrhagic Telangiectasia
23 December 2011
Objective: To evaluate the utility of transthoracic contrast echocardiography (TTCE) as a screening tool for pulmonary arteriovenous malformations (PAVMs) in children with hereditary hemorrhagic telan...
|
Suhail Al-Saleh,
Andreea Dragulescu,
David Manson,
Fraser Golding,
Jeffrey Traubici,
Meir Mei-Zahav,
Ian B. MacLusky,
Marie E. Faughnan,
Susan Carpenter,
Felix Ratjen
et al.
|
1039-1043.e1
|
|
|
|
Windows of Lead Exposure Sensitivity, Attained Height, and Body Mass Index at 48 Months
30 January 2012
Objective: To examine longitudinal associations of prenatal, infancy, and early childhood lead exposure during sensitive periods with height and body mass index (BMI). Study design: A total of 773 par...
|
Myriam Afeiche,
Karen E. Peterson,
Brisa N. Sánchez,
Lourdes Schnaas,
David Cantonwine,
Adrienne S. Ettinger,
Maritsa Solano-González,
Mauricio Hernández-Avila,
Howard Hu,
Martha M. Téllez-Rojo
et al.
|
1044-1049
|
|
| Clinical and Laboratory Observations |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Asking the Right Questions to Ascertain Early Childhood Secondhand Smoke Exposures
12 April 2012
Secondhand smoke is associated with a myriad of adverse health outcomes. Therefore, it is essential for clinicians to ask precise questions about exposures, particularly for children. We present 4 que...
|
Jocelyn M. Biagini Myers,
Gurjit K. Khurana Hershey,
Ranjan Deka,
Jeffrey W. Burkle,
Linda S. Levin,
David I. Bernstein,
Manuel Villareal,
James E. Lockey,
Tiina Reponen,
Joey Gareri,
Angelika Lubetsky,
Gideon Koren,
Grace K. LeMasters
et al.
|
1050-1051
|
|
|
|
Fatal Rhabdomyolysis in 2 Children with LPIN1 Mutations
06 April 2012
We report 2 cases of fatal rhabdomyolysis in children carrying an LPIN1 mutations preceded by similar electrocardiogram changes, including diffuse symmetrical high-amplitude T waves. Our report underl...
|
Jean Bergounioux,
Anais Brassier,
Caroline Rambaud,
Olivier Bustarret,
Caroline Michot,
Laurence Hubert,
Jean Baptiste Arnoux,
Annie Laquerriere,
Soumeya Bekri,
Sophie Galene-Gromez,
Damien Bonnet,
Philippe Hubert,
Pascale de Lonlay
et al.
|
1052-1054
|
|
|
|
A Patient with Tyrosine Kinase 2 Deficiency without Hyper-IgE Syndrome
09 March 2012
We describe a Turkish patient with tyrosine kinase 2 deficiency who suffered from disseminated Bacille Calmette-Guerin infection, neurobrucellosis, and cutaneous herpes zoster infection. Tyrosine kina...
|
Sara S. Kilic,
Mustafa Hacimustafaoglu,
Stéphanie Boisson-Dupuis,
Alexandra Y. Kreins,
Audrey V. Grant,
Laurent Abel,
Jean-Laurent Casanova
et al.
|
1055-1057
|
|
| Rediscovering the Physical Exam |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Hemifacial Flushing after Bathing and Crying
27 February 2012
An 8-month-old girl presented to our hospital with complaints of hemifacial flushing after bathing (). When she was 6 months old, her mother noticed that she had unilateral facial flushing and sweated...
|
Tadafumi Yokoyama,
Akiko Toga,
Yoko Hashida,
Yuka Wakabayashi,
Koji Hayashi,
Eiji Kato
et al.
|
1058-1059
|
|
| Insights |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Limbic Encephalitis in a Boy with N-Methyl-D-Aspartate Receptor Antibodies
16 February 2012
A 6-year-old previously healthy boy had a 48-hour history of severe disorientation and bizarre behavior (agitated, fearful), preceded by a mild prodromal 10-day headache. Vital signs and neurologic ex...
|
Nicholas M. Allen,
Bryan Lynch,
Eilish Twomey
|
1060
|
|
|
|
Skin Lesions and Lung Cysts in a Neonate
09 March 2012
An infant born at 33 weeks’ gestation with a prenatally diagnosed skin lesion developed respiratory distress immediately after birth. Initial resuscitation required intubation and surfactant administr...
|
Craig M. Forester,
Jefferson Terry,
Edward Y. Lee,
Tregony Simoneau,
Kenan Haver
et al.
|
1061-1061.e1
|
|
|
|
Declining School Performance as a Harbinger of a Treatable Neurodegenerative Condition
30 January 2012
On starting a new school year, an 11-year-old honors student began having difficulty focusing. His grades in mathematics declined, soon followed by a decline in other subjects. He began having visual ...
|
Pankaj Prasun,
Vinod K. Misra
|
1062-1062.e1
|
|
| Letters to the Editor |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Bed sharing and sudden infant death syndrome
16 April 2012
In a meta-analysis by Vennemann et al regarding bed sharing and the risk of sudden infant death syndrome (SIDS), the authors concluded that “bed sharing is a risk factor for SIDS.” Although many infan...
|
Roger W. Byard
|
1063
|
|
|
|
Reply
16 April 2012
Clear selection criteria were set before reviewing the reports on bed sharing and sudden infant death syndrome (SIDS). Only studies in which an adequate definition for SIDS was given and in which auto...
|
Ursula Kiechl-Kohlendorfer,
Mechtild M. Vennemann
|
1063
|
|
