The Journal of Pediatrics
Volume 132, Issue 2 , Pages 260-264 , February 1998

Relationship between socioeconomic status and disease severity in cystic fibrosis

Received 13 January 1997 ,Accepted 23 July 1997.

References 

  1. Collins FS. Cystic fibrosis: molecular biology and therapeutic implications. Science. 1992;256:774–779
  2. Wilmott RW, Fiedler MA. Recent advances in the treatment of cystic fibrosis. Pediatr Clin North Am. 1994;41:431–451
  3. Lester LA, Kraut J, Lloyd-Still J, Karrison T, Mott C, Billstrand C, et al.  Delta F508 genotype does not predict disease severity in an ethnically diverse cystic fibrosis population. Pediatrics. 1994;93:114–118
  4. Jolly DL, Nolan T, Moller J, Vimpani G. The impact of poverty and disadvantage on child health. J Paediatr Child Health. 1991;27:203–217
  5. Finkelstein JA, Brown RW, Schneider LC, Weiss ST, Quintana JM, Goldmann DA, et al.  Quality of care for preschool children with asthma: the role of social factors and practice setting. Pediatrics. 1995;95:389–394
  6. Britton J. Effects of social class, sex, and region of residence on age at death from cystic fibrosis. Br Med J. 1989;298:483–487
  7. Curtis JR, Burke W, Kassner A, Aitkin ML. Absence of health insurance and lower socioeconomic status decrease life expectancy in cystic fibrosis. [abstract] Am J Respir Crit Care Med. 1996;153:A72
  8. Kerem E, Reisman J, Corey M, Canny GJ, Levison H. Prediction of mortality in patients with cystic fibrosis. N Engl J Med. 1992;326:1187–1191
  9. Packe GE, Hodson ME. Changes in spirometry during consecutive admissions for infective pulmonary exacerbations in adolescent and adult cystic fibrosis. Respir Med. 1992;86:45–48
  10. Fitzsimmons SC. The changing epidemiology of cystic fibrosis. J Pediatr. 1993;122:1–9
  11. Frisancho AR. Anthropometric standard for the assessment of growth and nutritional status. In: Ann Arbor: University of Michigan Press; 1990;p. 163–169
  12. Liberatos P, Link BG, Kelsey JL. The measurement of social class in epidemiology. Epidemiol Rev. 1988;10:87–120
  13. Kerem E, Corey M, Kerem BS, Rommens J, Markiewicz D, Levison H, et al.  The relationship between genotype and phenotype in cystic fibrosis—analysis of the most common mutation (delta F508). N Engl J Med. 1990;323:1517–1522
  14. Konstan MW, Byard PJ, Hoppel CL, Davis PB. Effect of high-dose ibuprofen in patients with cystic fibrosis. N Engl J Med. 1995;332:848–854
  15. Fuchs HJ, Borowitz DS, Christiansen DH, Morris EM, Nash ML, Ramsey BW, et al.  Effect of aerosolized recombinant human DNA-ase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. N Engl J Med. 1994;331:637–642
  16. Bor DH, Epstein PR. Pathogenesis of respiratory infection in the disadvantaged. Semin Respir Infect. 1991;6:194–203
  17. Sexton K, Gong H, Bailar JC, Ford JG, Gold DR, Lambert WE, et al.  Air pollution health risks: Do class and race matter?. Toxicol Ind Health. 1993;9:843–878
  18. Haire-Joshu D, Morgan G, Fisher EB. Determinants of cigarette smoking. Clin Chest Med. 1991;4:711–724
  19. Hanrahan JP, Tager IB, Segal MR, Tosteson TD, Castile RG, Vunakis HV, et al.  The effect of maternal smoking during pregnancy on early lung function. Am Rev Respir Dis. 1992;149:1129–1135
  20. Patterson JM, McCubbin HI, Warwick WJ. The impact of family functioning on health changes in children with cystic fibrosis. Soc Sci Med. 1990;31:159–164
  21. Lask B. Non-adherence to treatment in cystic fibrosis. J R Soc Med. 1994;87(suppl 21):25–27
  22. Dimissie K, Ernst P, Hanley JA, Locher U, Menzies D, Becklake M. Socioeconomic status and lung function among primary school children in Canada. Am J Respir Crit Care Med. 1996;153:719–723

☆ From the Department of Pediatrics, Bowman Gray School of Medicine, Winston-Salem, North Carolina; and the Department of Pediatrics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina.

☆☆ Supported in part by a CF Foundation grant B873 (MSS).

★ Reprint requests: Michael S. Schechter, MD, MPH, Department of Pediatrics, Bowman Gray School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157.

★★ 9/21/85000

PII: S0022-3476(98)70442-1

The Journal of Pediatrics
Volume 132, Issue 2 , Pages 260-264 , February 1998

Article Tools

* Image Usage & Resolution