The Journal of Pediatrics
Volume 132, Issue 2 , Pages 249-254 , February 1998

A prospective, randomized, multicenter trial of high-frequency oscillatory ventilation compared with conventional ventilation in preterm infants with respiratory distress syndrome receiving surfactant

Received 8 August 1996 ,Accepted 22 April 1997.

References 

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  2. Cornish DJ, Gerstmann DR, Clark RH, Carter JM, Nell DM, DeLemos RA. Extracorporeal membrane oxygenation and high-frequency oscillatory ventilation: potential therapeutic relationships. Crit Care Med. 1987;15:831–834
  3. Carter JM, Gerstmann DR, Clark RH, et al.  High-frequency oscillatory ventilation and extracorporeal membrane oxygenation for the treatment of acute neonatal respiratory failure. Pediatrics. 1990;85:159–164
  4. Varnholt V, Lasch P, Suske W, Kachel W, Brands W. High-frequency oscillatory ventilation and extracorporeal membrane oxygenation in severe persistent pulmonary hypertension of the newborn. Eur J Pediatr. 1992;151:718–725
  5. HIFI Study Group . High-frequency oscillatory ventilation compared with conventional mechanical ventilation in the treatment of respiratory failure in preterm infants. N Engl J Med. 1989;320:88–93
  6. Froese AB. Treatment of respiratory failure in preterm infants. N Engl J Med. 1989;320:1694–1695
  7. Bryan AC, Froese AB. Reflections on the HIFI Trial. Pediatrics. 1991;87:565–567
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  9. HIFO Study Group . Randomized study of high-frequency oscillatory ventilation in infants with severe respiratory distress syndrome. J Pediatr. 1993;122:609–619
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  14. Nilsson R, Bergren P, Curstedt T, Grossmann G, Renheim G, Robertson B. Surfactant treatment and ventilation by high frequency oscillation in premature newborn rabbits: effect on survival, lung aeration, and bronchiolar epithelial lesions. Pediatr Res. 1985;19:143–147
  15. Walther F, Kuipers IM, Gidding CE, Willebrand D, Buchholtz RTF, Bevers EM. A comparison of high-frequency oscillation superimposed onto backup mechanical ventilation on the distribution of exogenous surfactant in premature lambs. Pediatr Res. 1987;22:725–729
  16. Heldt GP, Merritt A, Golembski D, Gilliard N, Bloor C, Spragg R. Distribution of surfactant, lung compliance, and aeration of preterm rabbit lungs after surfactant therapy and conventional and high-frequency oscillatory ventilation. Pediatr Res. 1992;31:270–275
  17. Meredith KS, deLemos RA, Coalson JJ, et al.  Role of lung injury in the pathogenesis of hyaline membrane disease in premature baboons. J Appl Physiol. 1989;66:2150–2158
  18. Hamilton PP, Onayemi A, Smyth JA, et al.  Comparison of conventional and high-frequency ventilation: oxygenation and lung pathology. J Appl Physiol. 1983;55:131–138
  19. Kolton M, Cattran CB, Kent G, Volgyesi G, Froese AB, Bryan AC. Oxygenation during high-frequency ventilation compared with conventional mechanical ventilation in two models of lung injury. Anesth Analg. 1982;61:323–332
  20. Groneck P, Götze-Speer B, Oppermann M, Eiffert H, Speer CP. Association of pulmonary inflammation and increased microvascular permeability during the development of bronchopulmonary dysplasia: a sequential analysis of inflammatory mediators in respiratory fluids of high-risk preterm neonates. Pediatrics. 1994;93:712–718

☆ From the Department of Pediatrics, Division of Neonatology, University Hospital Frankfurt a. Main, the Department of Pediatrics, University Hospital Cologne, and the Department of Pediatrics, University Hospital Mannheim, Federal Republic of Germany

☆☆ Reprint requests: Werner Rettwitz-Volk, MD, Zentrum der Kinderheilkunde, Abt. f. Neonatologie, Theodor Stern Kai 7, 60590 Frankfurt, Germany.

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The Journal of Pediatrics
Volume 132, Issue 2 , Pages 249-254 , February 1998

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