The Journal of Pediatrics
Volume 126, Issue 2 , Pages 171-177 , February 1995

Enhanced adrenomedullary response and increased susceptibility to neuroglycopenia: Mechanisms underlying the adverse effects of sugar ingestion in healthy children

Received 6 September 1994 ,Accepted 26 October 1994.

References 

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  14. DeFeo P, Gallai V, Mazzotta G, et al.  Modest decrements in plasma glucose concentrations cause early impairment in cognitive function and later activation of glucose counterregulation in the absence of hypoglycemic symptoms in normal man. J Clin Invest. 1988;82:436–444
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  16. Borg WP, During MJ, Sherwin RS, Borg MA, Brines ML, Shulman GI. Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia. J Clin Invest. 1994;93:1677–1682
  17. Biggers DW, Myers SR, Neal D, et al.  Role of brain in counterregulation of insulin-induced hypoglycemia. Diabetes. 1989;38:7–16
  18. Rosen LA, Booth SR, Bender ME, McGrath ML, Sorrel S, Drabman RS. Effects of sugar (sucrose) on children's behavior. J Consult Clin Psychol. 1988;57:583–589
  19. Goldman JA, Lerman RH, Contois JM, Udall JN. Behavioral effects of sucrose on preschool children. J Abnorm Child Psychol. 1986;14:565–577
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☆ From the Departments of Pediatrics, Internal Medicine, and Neurosurgery and the General Clinical Research Centers, Yale University School of Medicine, New Haven, Connecticut

☆☆ Supported by grants RR06022, RR00125, DK20495, and HD30671 from the National Institutes of Health and by a grant from the Juvenile Diabetes Foundation International.

★ Reprint requests: William V. Tamborlane, MD, Department of Pediatrics, Yale University School of Medicine, 333 Cedar St., New Haven, CT 06510-8064.

★★ 0022-3476/95/$3.00 + 0 9/20/61576

PII: S0022-3476(95)70541-4

The Journal of Pediatrics
Volume 126, Issue 2 , Pages 171-177 , February 1995

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