The Journal of Pediatrics
Volume 63, Issue 5 , Pages 904-915, November 1963

Acute hemolysis due to naphthalene inhalation1

    M.D., D.C.H.
  • Timos Valaes

      Affiliations

    • Department of Obstetrics and Gynaecology, University of Athens, Athens, Greece
    • Department of Clinical Therapeutics, University of Athens, Athens, Greece
    • Paediatric Unit of “Aghia Sophia” Children's Hospital, Athens, Greece
  • , M.D.
  • Spyros A. Doxiadis

      Affiliations

    • Address, Children's Hospital “Aghia Sophia”, Athens 609, Greece.
    • Department of Obstetrics and Gynaecology, University of Athens, Athens, Greece
    • Department of Clinical Therapeutics, University of Athens, Athens, Greece
    • Paediatric Unit of “Aghia Sophia” Children's Hospital, Athens, Greece
  • , M.D.
  • Phaedon Fessas

      Affiliations

    • Department of Obstetrics and Gynaecology, University of Athens, Athens, Greece
    • Department of Clinical Therapeutics, University of Athens, Athens, Greece
    • Paediatric Unit of “Aghia Sophia” Children's Hospital, Athens, Greece

Acute hemolytic episodes with the presence of Heinz bodies and fragmented erythrocytes occurred following inhalation of naphthalene in 21 newborn Greek infants. Glucose-6-phosphate dehydrogenase activity was deficient in the erythrocytes of 12 infants. Surprisingly, however, the activity of this enzyme was normal in the other 9.

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1 This work was supported by a research grant from Pfizer-Hellas and at its later stages by the Association for the Aid of Crippled Children.

PII: S0022-3476(63)80221-8

The Journal of Pediatrics
Volume 63, Issue 5 , Pages 904-915, November 1963