The Journal of Pediatrics
Volume 57, Issue 3 , Pages 461-470 , September 1960

Two new subvariants of virilizing adrenal hyperplasia

    M.D.
  • José Cara (Senior postdoctoral trainee)

      Affiliations

    • Division of General Medical Sciences, National Institutes of Health.
  • , M.D.
  • Lytt I. Gardner

      Affiliations

    • Address, Department of Pediatrics, State University of New York, Upstate Medical Center, 766 Irving Avenue, Syracuse 10, N. Y.

References 

  1. Butler AM, Ross RA, Talbot NB. Probable Adrenal Insufficiency in an Infant. J. Pediat. 1939;15:831
  2. Wilkins L, Fleischmann W, Howard JE. Macrogenitosomia Precox Associated With Hyperplasia of the Androgenic Tissue of Adrenal and Death From Corticoadrenal Insufficiency. Endocrinology. 1940;26:385
  3. White FP, Sutton LE. Adrenogenital Syndrome With Associated Episodes of Hypoglycemia. J. Clin. Endocrinol. 1951;11:1395
  4. Wilkins L, Crigler JF, Silverman SH, Gardner LI, Migeon CJ. Further Studies on the Treatment of Congenital Adrenal Hyperplasia With Cortisone. III. The Control of Hypertension With Cortisone, With a Discssion of Variations in the Type of Congenital Adrenal Hyperplasia and Report of a Case With Probable Defect of Carbohydrate-regulating Hormones. J. Clin. Endocrinol. 1952;12:1015
  5. Wilkins L, Lewis RA, Klein R, Gardner LI, Crigler JF, Rosemberg E, et al. Treatment of Congenital Adrenal Hyperplasia With Cortisone. J. Clin. Endocrinol. 1951;11:1
  6. Shepard TH, Clausen SW. Case of Adrenogenital Syndrome With Hypertension Treated With Cortisone. Pediatrics. 1951;8:805
  7. Wilkins Lawson. The Diagnosis and Treatment of Endocrine Disorders in Childhood and Adolescence. ed. 2. Springfield, Ill.: Charles C Thomas, Publishers; 1957;
  8. Talbot NB, Butler AM, Berman RA. Adrenal Cortical Hyperplasia With Virilism: Diagnosis, Course and Treatment. J. Clin. Invest. 1942;21:559
  9. Grumbach MM, Wilkins L. The Pathogenesis and Treatment of Virilizing Adrenal Hyperplasia. Pediatrics. 1956;17:418
  10. Wilkins L, Crigler JF, Silverman SH, Gardner LI, Migeon CJ. Further Studies on the Treatment of Congenital Adrenal Hyperplasia With Cortisone. II. The Effects of Cortisone on Sexual and Somatic Development, With an Hypothesis Concerning the Mechanism of Feminization. J. Clin. Endocrinol. 1952;12:277
  11. Gonzales RF, Gardner LI. Congenital Adrenal Hyperplasia With Associated Episodes Resembling Histamine Poisoning. Pediatrics. 1956;17:524
  12. Gardner LI, Migeon CJ. Unusual Plasma 17-Ketosteroid Pattern in a Boy With Congenital Adrenal Hyperplasia and Periodic Fever. J. Clin. Endocrinol. 1959;19:266
  13. Bongiovanni AM, Eberlein WR. Clinical and Metabolic Variations in the Adrenogenital Syndrome. Pediatrics. 1955;16:628
  14. Iversen T. Congenital Adrenocortical Hyperplasia With Disturbed Electrolyte Regulation “Dysadrenocorticism”. Pediatrics. 1955;16:875
  15. Gardner LI. Plasma Neutral 17-Ketosteroids. I. Technique of Estimation. J. Clin. Endocrinol. 1953;13:941
  16. Kappas A, Hellman L, Fukushima DK, Gallagher TF. The Pyrogenic Effect of Etiocholanolone. J. Clin. Endocrinol. 1957;17:451
  17. Bondy PK, Cohn GL, Hermann W, Crispell KR. The Possible Relationship of Etiocholanolone to Periodic Fever. Yale J. Biol. & Med. 1958;30:395
  18. Migeon CJ, Plager JE. A Method for the Fractionation and Measurement of 17-Ketosteroids in Human Plasma. J. Clin. Endocrinol. 1955;15:702
  19. Wilkins L, Cara J. Further Studies on the Treatment of Congenital Adrenal Hyperplasia With Cortisone. V. Effects of Cortisone Therapy on Testicular Development. J. Clin. Endocrinol. 1954;14:287
  20. Bongiovanni AM, Eberlein WR, Cara J. Studies on the Metabolism of Adrenal Steroids in the Adrenogenital Syndrome. J. Clin. Endocrinol. 1954;14:409
  21. Bongiovanni AM. In Vitro Hydroxylation of Steroids by Whole Adrenal Homogenates of Beef, Normal Man, and Patients With the Adrenogenital Syndrome. J. Clin. Invest. 1958;37:1342
  22. Childs B, Grumbach MM, Van Wyk JJ. Virilizing Adrenal Hyperplasia; a Genetic and Hormonal Study. J. Clin. Invest. 1956;35:221
  23. Bongiovanni AM, Eberlein WR. Defective Steroidal Biogenesis in Congenital Adrenal Hyperplasia. Pediatrics. 1958;21:661

*** This study was supported in part by Research Grant A-2504 (C1) and Training Grant 2G-346, National Institutes of Health, United States Public Health Service.Presented in part at the IX International Congress of Paediatrics, Montreal, Canada, July 19 to 25, 1959.

PII: S0022-3476(60)80254-5

The Journal of Pediatrics
Volume 57, Issue 3 , Pages 461-470 , September 1960