The Journal of Pediatrics
Volume 158, Issue 1 , Pages 15-19.e1 , January 2011

Exercise Performance in Adolescents with Autonomic Dysfunction

  • Barbara E.U. Burkhardt, MD

      Affiliations

    • Department of Pediatric Cardiology and Congenital Heart Disease, University Medical Center Freiburg, Freiburg, Germany
    • ,
  • Phil R. Fischer, MD

      Affiliations

    • Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN
    • ,
  • Chad K. Brands, MD

      Affiliations

    • Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN
    • ,
  • Co-burn J. Porter, MD

      Affiliations

    • Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN
    • ,
  • Amy L. Weaver, MS

      Affiliations

    • Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN
    • ,
  • Paul J. Yim, BA

      Affiliations

    • Mayo Clinic College of Medicine, Rochester, MN
    • ,
  • Paolo T. Pianosi, MD

      Affiliations

    • Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN
    • Corresponding Author InformationReprint requests: P.T. Pianosi, Department of Pediatric and Adolescent Medicine, Mayo Clinic, 200 First St. SW, Rochester MN, 55905.

Received 12 March 2010 ,Revised 1 June 2010 ,Accepted 12 July 2010.

References 

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  2. ter Wolbeek M, van Doornen LJ, Kavelaars A, Heijnen CJ. Severe fatigue in adolescents: a common phenomenon?. Pediatrics. 2006;117:e1078–e1086
  3. Prins JB, van der Meer JWM, Bleijenberg G. Chronic fatigue syndrome. Lancet. 2006;367:346–355
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  5. Galland BC, Jackson PM, Sayers RM, Taylor JB. A matched case control study of orthostatic intolerance in children/adolescents with chronic fatigue syndrome. Pediatr Res. 2008;63:196–202
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  8. Wyller VB, Due R, Saul JP, Amlie JP, Thaulow E. Usefulness of an abnormal cardiovascular response during low-grade head-up tilt-test for discriminating adolescents with chronic fatigue from healthy controls. Am J Cardiol. 2007;99:997–1001
  9. Wyller VB, Saul JP, Walloe L, Thaulow E. Sympathetic cardiovascular control during orthostatic stress and isometric exercise in adolescent chronic fatigue syndrome. Eur J Appl Physiol. 2008;102:623–632
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  12. Johnson JN, Mack KJ, Kuntz NL, Brands CK, Porter CJ, Fischer PR. Postural orthostatic tachycardia syndrome: a clinical review. Pediatr Neurol. 2010;42:77–85
  13. Stewart JM. Chronic orthostatic intolerance and the postural tachycardia syndrome. J Pediatr. 2004;145:725–730
  14. Stewart JM, Gewitz MH, Wedon A, Arlievsky N, Li K, Munoz J. Orthostatic intolerance in adolescent chronic fatigue syndrome. Pediatrics. 1999;103:116–121
  15. Fischer PR, Brands CK, Porter CJ, Kuntz NL, Mack KJ, Risma JM, et al. High prevalence of orthostatic intolerance in adolescents in a general pediatric referral clinic. Clin Autonom Res. 2005;15:340
  16. Skinner J, Driscoll S, Fischer P, Brands C, Kuntz N, Pianosi P, et al. Normal reference ranges for orthostatic changes in heart rate and blood pressure in adolescents. J Child Neurol (In press).
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  18. James FW, Kaplan S, Glueck CJ, Tsay J-Y, Knoght MJS, Sarwar CJ. Responses of normal children and young adults to controlled bicycle exercise. Circulation. 1980;61:902–912
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  21. Joyner MJ, Masuki S. POTS versus deconditioning: the same or different?. Clin Auton Res. 2008;18:300–307
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  25. In:  Bar-Or O,  Rowland TW editor. Pediatric exercise medicine. Champaign IL: Human Kinetics; 2004;p. 56–57
  26. Levine BD, Buckey JC, Fritsch JM, Yancy CW, Watenpaughjeter DE, Snell PG, et al. Physical Fitness and cardiovascular regulation: mechanisms of orthostatic intolerance. J Appl Physiol. 1991;70:112–122
  27. Smith ML, Raven PB. Cardiovascular responses to lower body negative pressure in endurance and static exercise-trained men. Med Sci Sports Exercise. 1986;18:545–550
  28. Convertino VA, Sather TM, Goldwater DJ, Alford WR. Aerobic fitness does not contribute to prediction of orthostatic tolerance. Med Sci Sports Exercise. 1986;18:551–556
  29. Masuki S, Eisenach JH, Schrage WG, Johnson CP, Dietz NM, Wilkins BW, et al. Reduced stroke volume during exercise in postural tachycardia syndrome. J Appl Physiol. 2007;103:1128–1135
  30. Masuki S, Eisenach JH, Schrage WG, Dietz NM, Johnson CP, Wilkins BW, et al. Arterial baroreflex control of heart rate during exercise in postural tachycardia syndrome. J Appl Physiol. 2007;103:1136–1142

 Funded in part by the American Dysautonomia Institute and the Huseby Family. The authors declare no conflicts of interest.

PII: S0022-3476(10)00598-6

doi: 10.1016/j.jpeds.2010.07.020

The Journal of Pediatrics
Volume 158, Issue 1 , Pages 15-19.e1 , January 2011

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