The Journal of Pediatrics
Volume 158, Issue 1 , Pages 31-36 , January 2011

Donation after Cardiac Death: The Potential Contribution of an Infant Organ Donor Population

  • Michelle Labrecque, RN, MSN

      Affiliations

    • Division of Newborn Medicine, Children's Hospital Boston, Boston, MA
    • ,
  • Richard Parad, MD, MPH

      Affiliations

    • Department of Newborn Medicine, Brigham and Women's Hospital, Boston, MA
    • Division of Newborn Medicine, Children's Hospital Boston, Boston, MA
    • Harvard Program in Neonatology, Harvard Medical School, Boston, MA
    • ,
  • Munish Gupta, MD, MMSc

      Affiliations

    • Department of Newborn Medicine, Beth Israel Deaconess Medical Center, Boston, MA
    • Division of Newborn Medicine, Children's Hospital Boston, Boston, MA
    • Harvard Program in Neonatology, Harvard Medical School, Boston, MA
    • ,
  • Anne Hansen, MD, MPH

      Affiliations

    • Division of Newborn Medicine, Children's Hospital Boston, Boston, MA
    • Harvard Program in Neonatology, Harvard Medical School, Boston, MA
    • Corresponding Author InformationReprint requests: Anne Hansen, MD, MPH, Children's Hospital, Division of Newborn Medicine, Hunnewell 4, 300 Longwood Ave, Boston, MA, 02115.

Received 10 March 2010 ,Revised 7 May 2010 ,Accepted 29 June 2010.

References 

  1. United Network for Organ Sharing: Transplant Trends. http://www.unos.org/. Accessed May 29, 2009.
  2. Penin H, Kaufer C. The dissociated brain death: clinical and electroencephalographic criteria for determination of death. Minn Med. 1968;51:1563–1567
  3. Moers C, Leuvenink HG, Ploeg RJ. Non-heart beating organ donation: overview and future perspectives. Transpl Int. 2007;20:567–575
  4. Howard RJ. Missed opportunities: the Institute of Medicine Report. Organ donation: opportunities for action. Am J Transplant. 2007;7:14–16
  5. Doshi MD, Hunsicker LG. Short- and long-term outcomes with the use of kidneys and livers donated after cardiac death. Am J Transplant. 2007;7:122–129
  6. Kowalski AE, Light JA, Ritchie WO, Sasaki TM, Callender CO, Gage F. A new approach for increasing the organ supply. Clin Transplant. 1996;10:653–657
  7. Organ Procurement and Transplantation Network, Regional Meeting Data Slides Fall 2006. http://optn.transplant.hrsa.gov/. Accessed May 29, 2009.
  8. Mazor R, Baden HP. Trends in pediatric organ donation after cardiac death. Pediatrics. 2007;120:e960–e966
  9. Boucek MM, Mashburn C, Dunn SM, Frizell R, Edwards L, Pietra B, et al. Pediatric heart transplantation after declaration of cardiocirculatory death. N Engl J Med. 2008;359:709–714
  10. Heron , Hoyert DL, Murphy SL, Xu JQ, Kochanek KD, Tejada-Vera B. Deaths: final data for 2006. National Vital Statistics Report. 2009;57:1–154
  11. Farrell MM, Levin DL. Brain death in the pediatric patient: historical, sociological, medical, religious, cultural, legal, and ethical considerations. Crit Care Med. 1993;21:1951–1965
  12. Durall AL, Laussen PC, Randolph AG. Potential for donation after cardiac death in a children's hospital. Pediatrics. 2007;119:e219–e224
  13. Koogler T, Costarino AT. The potential benefits of the pediatric non—heart-beating organ donor. Pediatrics. 1998;101:1049–1052
  14. Naim MY, Hoehn KS, Hasz RD, White LS, Helfaer MA, Nelson RM. The Children's Hospital of Philadelphia's experience with donation after cardiac death. Crit Care Med. 2008;36:1729–1733
  15. Pleacher KM, Roach ES, Van der Werf W, Antommaria AH, Bratton SL. Impact of a pediatric donation after cardiac death program. Pediatr Crit Care Med. 2009;10:166–170
  16. Webster PA, Markham L. Pediatric organ donation: a national survey examining consent rates and characteristics of donor hospitals. Pediatr Crit Care Med. 2009;10:500–504
  17. Antommaria AH, Trotochaud K, Kinlaw K, Hopkins PN, Frader J. Policies on donation after cardiac death at children's hospitals: a mixed-methods analysis of variation. JAMA. 2009;301:1902–1908
  18. Andrews PA. Renal transplantation. BMJ. 2002;324:530–534

 The authors declare no conflicts of interest.

PII: S0022-3476(10)00569-X

doi: 10.1016/j.jpeds.2010.06.055

The Journal of Pediatrics
Volume 158, Issue 1 , Pages 31-36 , January 2011

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