« Previous
Next »
The Journal of Pediatrics
Volume 157, Issue 3
, Pages 373-380.e1
, September 2010
Celiac Disease without Villous Atrophy in Children: A Prospective Study
References
- Prevalence of celiac disease among children in Finland. N Engl J Med. 2003;348:2517–2524
- A prospective study of the incidence of childhood celiac disease. J Pediatr. 2003;143:308–314
- . Revised criteria for diagnosis of celiac disease. Arch Dis Child. 1990;65:909–911
- Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. 2005;40:1–19
- The diagnostic accuracy of serologic tests for celiac disease: a systematic review. Gastroenterology. 2005;128:S38–S46
- . Normal small bowel biopsy followed by coeliac disease. Arch Dis Child. 1990;65:1137–1141
- . Changing jejunal γδ T cell receptor (TCR)-bearing intraepithelial lymphocyte density in coeliac disease. Clin Exp Immunol. 1999;117:51–55
- Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study. Arch Intern Med. 2003;163:286–292
- Clinical, HLA and small bowel immunohistochemical features of children with positive serum antiendomysium antibodies and architecturally normal small intestinal mucosa. Am J Gastroenterol. 2005;100:2294–2298
- . Gluten, major histocompatibility complex, and the small intestine: a molecular and immunobiologic approach to the spectrum of gluten sensitivity (“celiac sprue”). Gastroenterology. 1992;102:330–354
- . Seroconversion of reticulin autoantibodies predicts coeliac disease in insulin dependent diabetes mellitus. Gut. 1995;36:239–242
- . Latent coeliac disease in Italy. The SIGEP working group on latent coeliac disease. Italian Society for Paediatric Gastroenterology and Hepatology. Acta Paediatr. 1995;84:1252–1257
- Celiac disease: from inflammation to atrophy: a long-term follow-up study. J Pediatr Gastroenterol Nutr. 2005;41:44–48
- Diagnosing mild enteropathy celiac disease: a randomized, controlled clinical study. Gastroenterology. 2009;136:816–823
- A prospective, longitudinal study of the long-term effect of treatment on bone density in children with celiac disease. J Pediatr. 2001;139:516–521
- . Bone metabolism in celiac disease. J Pediatr. 2008;153:262–265
- . Endomysium antibodies in the diagnosis of celiac disease in short-statured children with no gastrointestinal symptoms. Pediatr Intern. 2001;43:71–73
- . Dental enamel defects in celiac disease. J Oral Pathol Med. 1990;19:241–245
- . Variability of histopathological changes in childhood celiac disease. Am J Gastroenterol. 2009;doi:10.1038/ajg.2009.557
- . Morphometric study of the jejunal mucosa in various childhood enteropathies with special reference to intraepithelial lymphocytes. J Pediatr Gastroenterol Nutr. 1982;1:525–531
- Intraepithelial lymphocytes in celiac disease. Am J Gastroenterol. 2003;98:1332–1337
- Molecular dissection of the tissue transglutaminase autoantibody response in celiac disease. J Immunol. 2001;166:4170–4176
- In vivo targeting of intestinal and extraintestinal transglutaminase 2 by coeliac autoantibodies. Gut. 2004;53:641–648
- Immunoglobulin A autoantibodies against transglutaminase 2 in the small intestinal mucosa predict forthcoming coeliac disease. Aliment Pharmacol Ther. 2006;24:541–552
- Small-bowel mucosal transglutaminase 2-specific IgA deposits in coeliac disease without villous atrophy: a prospective and randomized clinical study. Scand J Gastroenterol. 2005;40:564–572
- Immunoglobulin A anti-tissue transglutaminase antibody deposits in the small intestinal mucosa in children with no villous atrophy. J Pediatr Gastroenterol Nutr. 2008;47:293–298
- Gluten-dependent small bowel mucosal transglutaminase 2-specific IgA deposits in overt and mild enteropathy coeliac disease. J Pediatr Gastroenterol Nutr. 2008;47:436–442
- . Endomysium antibodies in coeliac disease: an improved method. Gut. 1994;35:776–778
- . IgA- and IgG class antihuman umbilical cord antibody tests in adult coeliac disease. Scand J Gastroenterol. 1998;33:251–254
- Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms. PLoS One. 2008;28(3):e2270
- . Intestinal gamma/delta receptor-bearing T lymphocytes in celiac disease and inflammatory bowel disease in children. Constant increase in celiac disease. Pediatr Res. 1990;28:579–581
- HLA types in celiac disease patients not carrying the DQA1*01-DQB1*02 (DQ2) heterodimer; results from the European genetics cluster on celiac disease. Hum Immunol. 2003;64:469–477
- Endomysial antibody-negative coeliac disease: clinical characteristics and intestinal autoantibody deposits. Gut. 2006;55:1746–1753
- . Mechanisms of abnormal puberty in coeliac disease. Horm Res. 2002;57:63–65
- Gynaecological and obstetric disorders in coeliac disease: frequent clinical onset during pregnancy or the puerperium. Eur J Gastroenterol Hepatol. 1996;8:63–89
- . Bone mineral density in children with celiac disease. Effect of a gluten-free diet. Eur J Clin Nutr. 2006;60:358–363
- . Better dietary compliance in patients with coeliac disease diagnosed in early childhood. Scand J Gastroenterol. 2003;38:751–754
- Quality of life in adolescents with treated coeliac disease: influence of compliance and age at diagnosis. J Pediatr Gastroenterol Nutr. 2008;47:555–561
- . Small-intestinal histopathology and mortality risk in celiac disease. JAMA. 2009;302:1171–1178
- . Celiac disease without villous atrophy: revision of criteria called for. Dig Dis Sci. 2001;46:879–887
- . The symptomatic and histologic response to a gluten-free diet in patients with borderline enteropathy. J Clin Gastroenterol. 2003;36:13–17
- . Patients with serum IgA endomysial antibodies and intact duodenal villi: clinical characteristic and management options. Scand J Gastroenterol. 2005;40:1240–1243
- . Italian paediatricians' approach to coeliac disease diagnosis. J Pediatr Gastroenterol Nutr. 2009;49:374–376
- . Quantitation of intraepithelial lymphocytes in human jejunum. Gut. 1971;12:988–994
- . Significance of intraepithelial lymphocytosis in small-bowel biopsy samples with normal mucosal architecture. Am J Gastroenterol. 2003;98:2027–2033
- Markers of potential coeliac disease in patients with Hashimoto's thyroiditis. Eur J Endocrinol. 2002;146:479–483
- IgA antibodies to tissue transglutaminase: an effective diagnostic test for celiac disease. J Pediatr. 1999;134:166–171
- Pre-endoscopy serological testing for coeliac disease: evaluation of a clinical decision tool. BMJ. 2007;334:729–732
Supported by the Academy of Finland Research Council for Health, the Competitive Research Funding of the Pirkanmaa Hospital District, the Sigrid Juselius Foundation, the Foundation for Paediatric Research, the EU Commission Marie Curie Excellence Grant (FP6 contract MEXT-CT-2005-025270), Marie Curie Mobility Grant (MRTNCT-2006-036032; TRACKS), the National Graduate School of Clinical Investigation, the Ehrnrooth Foundation, and the Finnish Coeliac Society. The study sponsors had no role in the study design or collection, analysis and interpretation of the data, writing of the article or the decision to submit the manuscript for publication. The authors declare no conflicts of interest.
PII: S0022-3476(10)00214-3
doi: 10.1016/j.jpeds.2010.02.070
© 2010 Mosby, Inc. All rights reserved.
« Previous
Next »
The Journal of Pediatrics
Volume 157, Issue 3
, Pages 373-380.e1
, September 2010
