The Journal of Pediatrics
Volume 156, Issue 6 , Pages 978-984.e1 , June 2010

Individual and Combined Effects of ApoE and MTHFR 677C/T Polymorphisms on Cognitive Performance in Spanish Adolescents: The AVENA Study

  • Jonatan R. Ruiz, PhD

      Affiliations

    • Unit for Preventive Nutrition, Department of Biosciences and Nutrition at NOVUM, Karolinska Institutet, Huddinge, Sweden
    • Corresponding Author InformationReprint requests: Dr Jonatan R. Ruiz, Department of Biosciences and Nutrition, Unit for Preventive Nutrition, Karolinska Institutet, Stockholm, Sweden. Hälsovägen 7-9, SE-141 57 Huddinge, Sweden.
    • ,
  • Ruth Castillo, PhD

      Affiliations

    • Department of Basic Psychology, School of Psychology, University of Málaga, Spain
    • ,
  • Idoia Labayen, PhD

      Affiliations

    • Department of Nutrition and Food Science, University of the Basque Country, Vitoria, Spain
    • ,
  • Luis A. Moreno, MD, PhD

      Affiliations

    • Department of Physiotherapy and Nursing, School of Health Sciences, University of Zaragoza, Zaragoza, Spain
    • ,
  • Miguel García Fuentes, MD, PhD

      Affiliations

    • Department of Pediatrics, University of Cantabria, Santander, Spain
    • ,
  • Domingo González Lamuño, MD, PhD

      Affiliations

    • Department of Pediatrics, University of Cantabria, Santander, Spain
    • ,
  • Jesus L. Alvarez Granda, MD, PhD

      Affiliations

    • Department of Pediatrics, University of Cantabria, Santander, Spain
    • ,
  • Alejandro Lucia, MD, PhD

      Affiliations

    • Universidad Europea de Madrid, Madrid, Spain
    • ,
  • Francisco B. Ortega, PhD

      Affiliations

    • Unit for Preventive Nutrition, Department of Biosciences and Nutrition at NOVUM, Karolinska Institutet, Huddinge, Sweden
    • Department of Medical Physiology, School of Medicine, University of Granada, Spain
    • ,
  • AVENA Study Group

Received 17 July 2009 ,Revised 25 September 2009 ,Accepted 9 December 2009.

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 Supported by the Spanish Ministry of Health (FIS No. 00/0015), grants from the Spanish Ministry of Education (EX-2007-1124; EX-2008-0641), grants from Panrico S.A., Madaus S.A., and Procter and Gamble S.A, the Swedish Council for Working Life and Social Research (FAS), the ALPHA study, a European Union–funded study, in the framework of the Public Health Programme (Ref: 2006120) the Spanish Ministry of Health: Maternal, Child Health and Development Network (No. RD08/0072). The authors declare no conflicts of interest.

PII: S0022-3476(09)01247-5

doi: 10.1016/j.jpeds.2009.12.018

The Journal of Pediatrics
Volume 156, Issue 6 , Pages 978-984.e1 , June 2010

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