Health-Related Quality of Life Across Pediatric Chronic Conditions

Objective

To compare health-related quality of life (HRQOL) across 8 pediatric chronic conditions, including 5 understudied populations, and examine convergence between youth self-report and parent-proxy report.

Study design

Secondary data from 589 patients and their caregivers were collected across the following conditions: obesity, eosinophilic gastrointestinal disorder, inflammatory bowel disease, epilepsy, type 1 diabetes, sickle cell disease, post–renal transplantation, and cystic fibrosis. Youth and caregivers completed age-appropriate self-report and/or parent-proxy report generic HRQOL measures.

Results

Youth diagnosed with eosinophilic gastrointestinal disorder and obesity had lower HRQOL than other pediatric conditions by parent report. Caregivers reported lower HRQOL by proxy report than youth self-reported across most subscales.

Conclusions

Use of brief, easily administered, and reliable assessments of psychosocial functioning, such as HRQOL, may provide clinicians additional opportunities for intervention or services targeting improved HRQOL relative to the needs of each population.

ANCOVA, Analysis of covariance, CF, Cystic fibrosis, EGID, Eosinophilic gastrointestinal disorder, FDA, Food and Drug Administration, HRQOL, Health-related quality of life, IBD, Inflammatory bowel disease, MANCOVA, Multivariate analysis of covariance, PedsQL, Pediatric Quality of Life Inventory, SCD, Sickle cell disease