The Journal of Pediatrics
Volume 155, Issue 6 , Pages 781-787.e1 , December 2009

Risk of Childhood Asthma in Relation to the Timing of Early Child Care Exposures

  • Matthew J. Gurka, PhD

      Affiliations

    • Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA
    • Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA
    • Corresponding Author InformationReprint requests: Matthew J. Gurka, PhD, Division of Biostatistics and Epidemiology, Department of Public Health Sciences, University of Virginia School of Medicine, PO Box 800717, Charlottesville, VA 22908-0717.
  • ,
  • James A. Blackman, MD, MPH

      Affiliations

    • Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA
  • ,
  • Peter W. Heymann, MD

      Affiliations

    • Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA

Received 12 December 2008 ,Revised 20 May 2009 ,Accepted 12 June 2009.

  • Image Result

    Model-predicted probability of asthma (persistent or late-onset) by number of other children in the child-care environment as a toddler. Predicted probability as a function of mean number of other chi

    Model-predicted probability of asthma (persistent or late-onset) by number of other children in the child-care environment as a toddler. Predicted probability as a function of mean number of other children in the child care setting as a toddler, with the final logistic model (Table IV), adjusting for all of the listed covariates. This figure presents specific probabilities for a Caucasian male whose mother did not report having asthma in a “clean” household who had 4 and 5 respiratory infections as an infant and toddler, respectively, who was not preterm, does not have eczema, and was breastfed, who was in primary care 32 hours per week in the first 3 years, who was around 2 other children in the primary care setting as an infant, with a mother with 14 years of education and is 29 years old and did not smoke during pregnancy, from an urban household with an income-to-needs ratio of 3 (all values are medians from the dataset). This overall relationship would remain no matter what values were chosen for the other covariates.

 Funded by NICHD grant R03-HD055298. The authors declare no potential, perceived, or real conflicts of interest.

PII: S0022-3476(09)00579-4

doi: 10.1016/j.jpeds.2009.06.035

The Journal of Pediatrics
Volume 155, Issue 6 , Pages 781-787.e1 , December 2009