The Journal of Pediatrics
Volume 155, Issue 6 , Pages 841-847.e1 , December 2009

Intravenous Sildenafil in the Treatment of Neonates with Persistent Pulmonary Hypertension

  • Robin H. Steinhorn, MD

      Affiliations

    • Department of Pediatrics, Northwestern University Feinberg School of Medicine and Children's Memorial Hospital, Chicago, IL
    • Corresponding Author InformationReprint requests: Robin H. Steinhorn, MD, Children's Memorial Hospital, 2300 Children's Plaza, Box 45, Chicago, IL 60614.
  • ,
  • John P. Kinsella, MD

      Affiliations

    • Department of Pediatrics, University of Colorado and The Children's Hospital, Denver, CO
  • ,
  • Christine Pierce, MD

      Affiliations

    • Paediatric and Neonatal Intensive Care Unit, Great Ormond Street Hospital for Children, London, UK
  • ,
  • Ghazwan Butrous, MB, PhD

      Affiliations

    • Division of Cardiopulmonary Sciences, University of Kent, Canterbury, UK
  • ,
  • Maria Dilleen, MSc

      Affiliations

    • Pfizer Global Research and Development, Sandwich, UK
  • ,
  • Michael Oakes, MSc, PhD

      Affiliations

    • Pfizer Global Research and Development, Sandwich, UK
  • ,
  • David L. Wessel, MD

      Affiliations

    • Department of Pediatrics, Children's National Medical Center, Washington, DC

Received 3 February 2009 ,Revised 8 May 2009 ,Accepted 8 June 2009.

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 The study sponsor (Pfizer) provided the intravenous sildenafil, financial support for the clinical research nurse and other costs of conducting the study at each site, as well as ongoing site monitoring. The data analysis was performed by the academic authors and reviewed by statisticians who are employees of Pfizer (M.D. and M.O.). The manuscript was prepared by R.H.S., G.B., and J.P.K. No honorarium or other payment was provided to produce the manuscript.

PII: S0022-3476(09)00560-5

doi: 10.1016/j.jpeds.2009.06.012

The Journal of Pediatrics
Volume 155, Issue 6 , Pages 841-847.e1 , December 2009