The Journal of Pediatrics
Volume 155, Issue 4 , Pages 464-465 , October 2009

Patience Is a Virtue in the Management of Gastroesophageal Reflux

  • Reese H. Clark, MD

      Affiliations

    • Corresponding Author InformationReprint requests: Reese H. Clark, MD, The Pediatrix Center for Research and Education, Pediatrix Medical Group, 1301 Concord Terrace, Sunrise, FL 33323-2825.

References 

  1. Wheatley E, Kennedy KA. Cross-over trial of treatment for bradycardia attributed to gastroesophageal reflux in preterm infants. J Pediatr. 2009;155:516–521
  2. Hibbs AM, Lorch SA. Metoclopramide for the treatment of gastroesophageal reflux disease in infants: a systematic review. Pediatrics. 2006;118:746–752
  3. Slocum C, Hibbs AM, Martin RJ, Orenstein SR. Infant apnea and gastroesophageal reflux: a critical review and framework for further investigation. Curr Gastroenterol Rep. 2007;9:219–224
  4. Malcolm WF, Gantz M, Martin RJ, Goldstein RF, Goldberg RN, Cotten CM. Use of medications for gastroesophageal reflux at discharge among extremely low birth weight infants. Pediatrics. 2008;121:22–27
  5. Poets CF. Gastroesophageal reflux: a critical review of its role in preterm infants. Pediatrics. 2004;113:e128–e132
  6. Peter CS, Sprodowski N, Bohnhorst B, Silny J, Poets CF. Gastroesophageal reflux and apnea of prematurity: no temporal relationship. Pediatrics. 2002;109:8–11
  7. Di Fiore JM, Arko M, Whitehouse M, Kimball A, Martin RJ. Apnea is not prolonged by acid gastroesophageal reflux in preterm infants. Pediatrics. 2005;116:1059–1063
  8. Martin RJ, Hibbs AM. Diagnosing gastroesophageal reflux in preterm infants. Pediatrics. 2006;118:793–794
  9. Magista AM, Indrio F, Baldassarre M, Bucci N, Menolascina A, Mautone A, et al. Multichannel intraluminal impedance to detect relationship between gastroesophageal reflux and apnoea of prematurity. Dig Liver Dis. 2007;39:216–221
  10. Corvaglia L, Zama D, Gualdi S, Ferlini M, Aceti A, Faldella G. Gastroesophageal reflux increases the number of apneas in very preterm infants. Arch Dis Child Fetal Neonatal Ed. 2008;In press
  11. Slocum C, Arko M, Di FJ, Martin RJ, Hibbs AM. Apnea, bradycardia and desaturation in preterm infants before and after feeding. J Perinatol. 2009;29:209–212
  12. Jobe AH. Too many unvalidated new therapies to prevent chronic lung disease in preterm infants. J Pediatr. 1998;132:200–202
  13. FDA. Available at: http://www.fda.gov/medwatch/safety/2009/safety09.htm#Metoclopramide. Accessed June 8, 2009.
  14. Guillet R, Stoll BJ, Cotten CM, Gantz M, McDonald S, Poole WK, et al. Association of H2-blocker therapy and higher incidence of necrotizing enterocolitis in very low birth weight infants. Pediatrics. 2006;117:e137–e142
  15. Clark RH, Bloom BT, Spitzer AR, Gerstmann DR. Reported medication use in the neonatal intensive care unit: data from a large national data set. Pediatrics. 2006;117:1979–1987
  16. Martin RJ, Di Fiore JM, Hibbs AM. Gastroesophageal reflux in preterm infants: is positioning the answer?. J Pediatr. 2007;151:560–561
  17. Peter CS, Sprodowski N, Ahlborn V, Wiechers C, Schlaud M, Silny J, et al. Inter- and intraobserver agreement for gastroesophageal reflux detection in infants using multiple intraluminal impedance. Biol Neonate. 2004;85:11–14

PII: S0022-3476(09)00495-8

doi: 10.1016/j.jpeds.2009.05.014

The Journal of Pediatrics
Volume 155, Issue 4 , Pages 464-465 , October 2009

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