The Journal of Pediatrics
Volume 155, Issue 5 , Pages 640-645.e2 , November 2009

Automated Adjustment of Inspired Oxygen in Preterm Infants with Frequent Fluctuations in Oxygenation: A Pilot Clinical Trial

  • Nelson Claure, MSc, PhD

      Affiliations

    • Corresponding Author InformationReprint requests: Nelson Claure, Division of Neonatology, Department of Pediatrics, University of Miami School of Medicine, PO Box 016960 R-131, Miami, FL 33101.
    • ,
  • Carmen D'Ugard, RRT
    • ,
  • Eduardo Bancalari, MD

Received 16 December 2008 ,Revised 31 March 2009 ,Accepted 24 April 2009.

References 

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  7. Esquer C, Claure N, D'Ugard C, Wada Y, Bancalari E. The role of abdominal muscle activity on the duration and severity of hypoxemia episodes in mechanically ventilated preterm infants. Neonatology. 2007;92:182–186
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  14. Sun Y, Kohane IS, Stark AR. Computer-assisted adjustment of inspired oxygen concentration improves control of oxygen saturation in newborn infants requiring mechanical ventilation. J Pediatr. 1997;131:754–756
  15. Claure N, Gerhardt T, Everett R, Musante G, Herrera C, Bancalari E. Closed-loop controlled inspired oxygen concentration for mechanically ventilated very low birth weight infants with frequent episodes of hypoxemia. Pediatrics. 2001;107:1120–1124
  16. Urschitz MS, Horn W, Seyfang A, Hallenberger A, Herberts T, Miksch S, et al. Automatic control of the inspired oxygen fraction in preterm infants: a randomized crossover trial. Am J Respir Crit Care Med. 2004;170:1095–1100
  17. Saugstad OD. Oxygen radical disease in neonatology. Semin Neonatol. 1998;3:229–238

 Supported by Viasys Healthcare, The University of Miami “Project: New Born,” and The Bank of America Charitable Foundation. Presented in part at the 2007 meeting of the Society for Pediatric Research. The authors have a patent on the algorithm used to automatically adjust the inspired oxygen. The University of Miami, the assignee for this patent, has a license agreement with Viasys Healthcare. Viasys Healthcare and Masimo Corporation have supported post-graduate educational activities at the University of Miami.

PII: S0022-3476(09)00453-3

doi: 10.1016/j.jpeds.2009.04.057

The Journal of Pediatrics
Volume 155, Issue 5 , Pages 640-645.e2 , November 2009

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