The Journal of Pediatrics
Volume 155, Issue 4 , Pages 535-541.e1 , October 2009

Persistence of the Metabolic Syndrome Over 3 Annual Visits in Overweight Hispanic Children: Association with Progressive Risk for Type 2 Diabetes

  • Emily E. Ventura, PhD

      Affiliations

    • Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA
    • ,
  • Christianne J. Lane, MS

      Affiliations

    • Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA
    • ,
  • Marc J. Weigensberg, MD

      Affiliations

    • Department of Pediatrics, LAC + USC Medical Center, Los Angeles, CA
    • ,
  • Claudia M. Toledo-Corral, MS

      Affiliations

    • Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA
    • ,
  • Jaimie N. Davis, PhD

      Affiliations

    • Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA
    • ,
  • Michael I. Goran, PhD

      Affiliations

    • Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA
    • Corresponding Author InformationReprint requests: Michael I. Goran, 2250 Alcazar Street, CSC 212, Los Angeles, CA 90089-2211.

Received 6 December 2008 ,Revised 10 March 2009 ,Accepted 3 April 2009.

References 

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  2. Cruz ML, Bergman RN, Goran MI. Unique effect of visceral fat on insulin sensitivity in obese Hispanic children with a family history of type 2 diabetes. Diabetes Care. 2002;25:1631–1636
  3. Goran MI, Bergman RN, Gower BA. Influence of total versus visceral fat on insulin action and secretion in African-American and white children. Obes Res. 2001;9:423–431
  4. Goran MI, Ball GD, Cruz ML. Obesity and risk of type 2 diabetes and cardiovascular disease in children and adolescents. J Clin Endocrinol Metab. 2003;88:1417–1427
  5. Goran MI, Bergman RN, Cruz ML, Watanabe R. Insulin resistance and associated compensatory responses in African-American and Hispanic children. Diabetes Care. 2002;25:2184–2190
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 Supported by grants from the National Institutes of Health (R01 DK 59211), the General Clinical Research Center's National Center for Research Resources (MO1 RR 00043), and the National Cancer Institute's Center for Transdisciplinary Research on Energetics and Cancer (U54 CA 116848).

 The authors declare no conflicts of interest.

PII: S0022-3476(09)00363-1

doi: 10.1016/j.jpeds.2009.04.008

The Journal of Pediatrics
Volume 155, Issue 4 , Pages 535-541.e1 , October 2009

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