The Journal of Pediatrics
Volume 154, Issue 5 , Pages 635-636 , May 2009

Lung Recruitment for Ventilation: Does It Work, and is It Safe?

  • Alan H. Jobe, MD, PhD

      Affiliations

    • Corresponding Author InformationReprint requests: Alan H. Jobe, MD, PhD, Cincinnati Children's Hospital, Division of Pulmonary Biology, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229-3039

References 

  1. Gattinoni L, Caironi P, Cressoni M, Chiumello D, Ranieri VM, Quintel M, et al. Lung recruitment in patients with the acute respiratory distress syndrome. N Engl J Med. 2006;354:1775–1786
  2. Meade MO, Cook DJ, Guyatt GH, Slutsky AS, Arabi YM, Cooper DJ, et al. Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. JAMA. 2008;299:637–645
  3. Mercat A, Richard JC, Vielle B, Jaber S, Osman D, Diehl JL, et al. Positive end-expiratory pressure setting in adults with acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. JAMA. 2008;299:646–655
  4. Fan E, Wilcox ME, Brower RG, Stewart TE, Mehta S, Lapinsky SE, et al. Recruitment maneuvers for acute lung injury: a systematic review. Am J Respir Crit Care Med. 2008;178:1156–1163
  5. Jobe AH. Why surfactant works for respiratory distress syndrome. NeoReviews 7. 2006;e95–e105
  6. de Jaegere A, van Veenendaal MB, Michiels A, van Kaam AH. Lung recruitment using oxygenation during open-lung high-frequency ventilation in preterm infants. Am J Respir Crit Care Med. 2006;174:639–645
  7. Barrington KJ, Dempsey EM. Cardiovascular support in the preterm: treatments in search of indications. J Pediatr. 2006;148:289–291
  8. de Waal K, Evans N, van der Lee J, van Kaam A. Effect of lung recruitment on pulmonary, systemic and ductal blood flow in preterm infants. J Pediatr. 2009;154:651–655
  9. Hillman NH, Moss TJ, Kallapur SG, Bachurski C, Pillow JJ, Polglase GR, et al. Brief, large tidal volume ventilation initiates lung injury and a systemic response in fetal sheep. Am J Respir Crit Care Med. 2007;176:575–581

 The concepts described herein were developed in part based on research supported by National Institutes of Health Grant HD-12714.

PII: S0022-3476(09)00055-9

doi: 10.1016/j.jpeds.2009.01.059

The Journal of Pediatrics
Volume 154, Issue 5 , Pages 635-636 , May 2009

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