The Journal of Pediatrics
Volume 154, Issue 3 , Pages 313-315 , March 2009

The Tip of the Iceberg: The Prevalence of Functional Gastrointestinal Diseases in Children

  • Samuel Nurko, MD, MPH

      Affiliations

    • Corresponding Author InformationReprint requests: Samuel Nurko, MD, MPH, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115

References 

  1. Nurko S, Di Lorenzo C. Functional abdominal pain: time to get together and move forward. J Pediatr Gastroenterol Nutr. 2008;47:679–680
  2. Rasquin A, Di Lorenzo C, Forbes D, Guiraldes E, Hyams JS, Staiano A, et al. Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology. 2006;130:1527–1537
  3. Levy RL, Olden KW, Naliboff BD, Bradley LA, Francisconi C, Drossman DA, et al. Psychosocial aspects of the functional gastrointestinal disorders. Gastroenterology. 2006;130:1447–1458
  4. Starfield B, Hoekelman RA, McCormick M, Benson P, Mendenhall RC, Moynihan C, et al. Who provides health care to children and adolescents in the United States?. Pediatrics. 1984;74:991–997
  5. Youssef NN, Atienza K, Langseder AL, Strauss RS. Chronic abdominal pain and depressive symptoms: analysis of the national longitudinal study of adolescent health. Clin Gastroenterol Hepatol. 2008;6:329–332
  6. Hotopf M, Carr S, Mayou R, Wadsworth M, Wessely S. Why do children have chronic abdominal pain, and what happens to them when they grow up? (Population-based cohort study). BMJ. 1998;316:1196–1200
  7. Lamdin DJ. Evidence of student attendance as an independent variable in education production functions. J Educ Res. 1996;89:115–162
  8. Frank L, Kleinman L, Rentz A, Ciesla G, Kim JJ, Zacker C. Health-related quality of life associated with irritable bowel syndrome: comparison with other chronic diseases. Clin Ther. 2002;24:675–689
  9. Stordal K, Nygaard EA, Bentsen BS. Recurrent abdominal pain: a five-year follow-up study. Acta Paediatr. 2005;94:234–236
  10. Drossman DA, Camilleri M, Mayer EA, Whitehead WE. AGA technical review on irritable bowel syndrome. Gastroenterology. 2002;123:2108–2131
  11. Mayer EA. Clinical practice: irritable bowel syndrome. N Engl J Med. 2008;358:1692–1699
  12. Saps M, Seshadri R, Sztainberg M, Schaffer G, Marshall BM, Di Lorenzo C. A prospective school-based study of abdominal pain and other common somatic complaints in children. J Pediatr. 2009;154:322–326
  13. Teitelbaum JE, Sinha P, Micale M, Yeung S, Jaeger J. Obesity is related to multiple fucntional abdominal diseases. J Pediatr. 2009;154:444–446
  14. Ramchandani PG, Hotopf M, Sandhu B, Stein A. The epidemiology of recurrent abdominal pain from 2 to 6 years of age: results of a large, population-based study. Pediatrics. 2005;116:46–50
  15. Hyams JS, Burke G, Davis PM, Rzepski B, Andrulonis PA. Abdominal pain and irritable bowel syndrome in adolescents: a community-based study. J Pediatr. 1996;129:220–226
  16. Walker LS, Baber KF, Garber J, Smith CA. A typology of pain coping strategies in pediatric patients with chronic abdominal pain. Pain. 2008;137:266–275
  17. Ramchandani PG, Stein A, Hotopf M, Wiles NJ. Early parental and child predictors of recurrent abdominal pain at school age: results of a large population-based study. J Am Acad Child Adolesc Psychiatry. 2006;45:729–736
  18. Ramchandani PG, Fazel M, Stein A, Wiles N, Hotopf M. The impact of recurrent abdominal pain: predictors of outcome in a large population cohort. Acta Paediatr. 2007;96:697–701
  19. Levy RL, Langer SL, Walker LS, Feld LD, Whitehead WE. Relationship between the decision to take a child to the clinic for abdominal pain and maternal psychological distress. Arch Pediatr Adolesc Med. 2006;160:961–965
  20. Youssef NN, Murphy TG, Schuckalo S, Intile C, Rosh J. School nurse knowledge and perceptions of recurrent abdominal pain: opportunity for therapeutic alliance?. Clin Pediatr (Phila). 2007;46:340–344
  21. Ho W, Spiegel MR. The relationship between obesity and fucntional gastrointestinal disorders: causation, association, or neither. Gastroenterol Hepatol. 2008;4:572–578
  22. Fishman L, Lenders C, Fortunato C, Noonan C, Nurko S. Increased prevalence of constipation and fecal soiling in a population of obese children. J Pediatr. 2004;145:253–254
  23. Pashankar DS, Loening-Baucke V. Increased prevalence of obesity in children with functional constipation evaluated in an academic medical center. Pediatrics. 2005;116:e377–e380
  24. Cook MB, Greenwood DC, Hardie LJ, Wild CP, Forman D. A systematic review and meta-analysis of the risk of increasing adiposity on Barrett's esophagus. Am J Gastroenterol. 2008;103:292–300
  25. Theisen J, Nehra D, Citron D, Johansson J, Hagen JA, Crookes PF, et al. Suppression of gastric acid secretion in patients with gastroesophageal reflux disease results in gastric bacterial overgrowth and deconjugation of bile acids. J Gastrointest Surg. 2000;4:50–54
  26. Tschop M, Weyer C, Tataranni PA, Devanarayan V, Ravussin E, Heiman ML. Circulating ghrelin levels are decreased in human obesity. Diabetes. 2001;50:707–709
  27. Horvath TL, Diano S, Sotonyi P, Heiman M, Tschop M. Minireview: ghrelin and the regulation of energy balance—a hypothalamic perspective. Endocrinology. 2001;142:4163–4169
  28. Foster A, Laws HL, Gonzalez QH, Clements RH. Gastrointestinal symptomatic outcome after laparoscopic Roux-en-Y gastric bypass. J Gastrointest Surg. 2003;7:750–753

PII: S0022-3476(08)00979-7

doi: 10.1016/j.jpeds.2008.11.012

The Journal of Pediatrics
Volume 154, Issue 3 , Pages 313-315 , March 2009

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