The Journal of Pediatrics
Volume 154, Issue 1 , Pages 126-131.e3 , January 2009

Ex Utero Intrapartum Treatment Procedure: A Peripartum Management Strategy in Particularly Challenging Cases

  • Lee M. Morris, MD
    • ,
  • Foong-Yen Lim, MD
    • ,
  • Timothy M. Crombleholme, MD

      Affiliations

    • Corresponding Author InformationReprint requests: Timothy M. Crombleholme, MD, The Fetal Care Center of Cincinnati, Division of Pediatric General, Thoracic and Fetal Surgery, Cincinnati Children's Hospital, 3333 Burnet Ave, MLC 2023, Cincinnati, OH 45229-3039

Received 28 May 2008 ,Revised 4 August 2008 ,Accepted 24 September 2008.

References 

  1. Anderson N, Boswell O, Duff G. Prenatal sonography for the detection of fetal anomalies: results of a prospective study and comparison with prior series. AJR Am J Roentgenol. 1995;165:943–950
  2. Langer JC, Tabb T, Thompson P, Paes BA, Caco CC. Management of prenatally diagnosed tracheal obstruction: access to the airway in utero prior to delivery. Fetal Diagn Ther. 1992;7:12–16
  3. Catalano PJ, Urken ML, Alvarez M, Norton K, Wedgewood J, Holzman I, et al. New approach to the management of airway obstruction in “high risk” neonates. Arch Otolaryngol Head Neck Surg. 1992;118:306–309
  4. Harrison MR, Adzick NS, Flake AW, VanderWall KJ, Bealer JF, Howell LJ, et al. Correction of congenital diaphragmatic hernia in utero VIII: Response of the hypoplastic lung to tracheal occlusion. J Pediatr Surg. 1996;31:1339–1348
  5. Moore TR, Cayle JE. The amniotic fluid index in normal human pregnancy. Am J Obstet Gynecol. 1990;162:1168–1173
  6. Rypens F, Metens T, Rocourt N, Sonigo P, Brunelle F, Quere MP, et al. Fetal lung volume: estimation at MR imaging-initial results. Radiology. 2001;219:236–241
  7. Mielke G, Benda N. Cardiac output and central distribution of blood flow in the human fetus. Circulation. 2001;103:1662–1668
  8. Paladini D, Morra T, Teodoro A, Lamberti A, Tremolaterra F, Martinelli P. Objective diagnosis of micrognathia in the fetus: the jaw index. Obstet Gynecol. 1999;93:382–386
  9. Hubbard AM, Crombleholme TM, Adzick NS. Prenatal MRI evaluation of giant neck masses in preparation for the fetal exit procedure. Am J Perinatol. 1998;15:253–257
  10. Hedrick MH, Ferro MM, Filly RA, Flake AW, Harrison MR, Adzick NS. Congenital high airway obstruction syndrome (CHAOS): a potential for perinatal intervention. J Pediatr Surg. 1994;29:271–274
  11. Lim FY, Crombleholme TM, Hedrick HL, Flake AW, Johnson MP, Howell LJ, et al. Congenital high airway obstruction syndrome: natural history and management. J Pediatr Surg. 2003;38:940–945
  12. Kunisaki SM, Barnewolt CE, Estroff JA, Myers LB, Fauza DO, Wilkins-Haug LE, et al. Ex utero intrapartum treatment with extracorporeal membrane oxygenation for severe congenital diaphragmatic hernia. J Pediatr Surg. 2007;42:98–104discussion 105-6
  13. Vettraino IM, Lee W, Bronsteen RA, Harper CE, Aughton D, Comstock CH. Clinical outcome of fetuses with sonographic diagnosis of isolated micrognathia. Obstet Gynecol. 2003;102:801–805
  14. Albanese CT. The EXIT Strategy. NeoReviews. 2005;(6):e431–e435
  15. Marwan A, Crombleholme TM. The EXIT procedure: principles, pitfalls, and progress. Semin Pediatr Surg. 2006;15:107–115

 The authors declare no potential conflicts of interest, real or perceived.

PII: S0022-3476(08)00816-0

doi: 10.1016/j.jpeds.2008.09.044

The Journal of Pediatrics
Volume 154, Issue 1 , Pages 126-131.e3 , January 2009

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