The Journal of Pediatrics
Volume 154, Issue 2 , Pages 258-262 , February 2009

Health Utilization and Cost Impact of Childhood Constipation in the United States

  • Olivia Liem, MD

      Affiliations

    • Division of Pediatric Gastroenterology, Nationwide Children's Hospital, Columbus, OH
    • Department of Pediatric Gastroenterology and Nutrition, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands
    • Corresponding Author InformationReprint requests: Olivia Liem, MD, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    • ,
  • Jeffrey Harman, PhD

      Affiliations

    • Department of Health Services Research, Management and Policy College of Public Health and Health Professions, and University of Florida, Gainesville, FL
    • ,
  • Marc Benninga, MD, PhD

      Affiliations

    • Department of Pediatric Gastroenterology and Nutrition, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands
    • ,
  • Kelly Kelleher, MD

      Affiliations

    • Division of Pediatric Gastroenterology, Nationwide Children's Hospital, Columbus, OH
    • ,
  • Hayat Mousa, MD

      Affiliations

    • Division of Pediatric Gastroenterology, Nationwide Children's Hospital, Columbus, OH
    • ,
  • Carlo Di Lorenzo, MD

      Affiliations

    • Division of Pediatric Gastroenterology, Nationwide Children's Hospital, Columbus, OH

Received 11 January 2008 ,Revised 9 June 2008 ,Accepted 31 July 2008.

References 

  1. van den Berg MM, Benninga MA, Di Lorenzo C. Epidemiology of childhood constipation: a systematic review. Am J Gastroenterol. 2006;101:2401–2409
  2. van Ginkel R, Reitsma JB, Buller HA, van Wijk MP, Taminiau JA, Benninga MA. Childhood constipation: longitudinal follow-up beyond puberty. Gastroenterology. 2003;125:357–363
  3. Youssef NN, Langseder AL, Verga BJ, Mones RL, Rosh JR. Chronic childhood constipation is associated with impaired quality of life: a case-controlled study. J Pediatr Gastroenterol Nutr. 2005;41:56–60
  4. Martin BC, Barghout V, Cerulli A. Direct medical costs of constipation in the United States. Manag Care Interface. 2006;19:43–49
  5. Singh G, Lingala V, Wang H, Vadhavkar S, Kahler KH, Mithal A, et al. Use of health care resources and cost of care for adults with constipation. Clin Gastroenterol Hepatol. 2007;5:1053–1058
  6. Guevara JP, Mandell DS, Rostain AL, Zhao H, Hadley TR. National estimates of health services expenditures for children with behavioral disorders: an analysis of the medical expenditure panel survey. Pediatrics. 2003;112:e440
  7. Li S, Leader S. Economic burden and absenteeism from influenza-like illness in healthy households with children (5-17 years) in the US. Respir Med. 2007;101:1244–1250
  8. Chan E, Zhan C, Homer CJ. Health care use and costs for children with attention-deficit/hyperactivity disorder: national estimates from the Medical Expenditure Panel Survey. Arch Pediatr Adolesc Med. 2002;156:504–511
  9. Agency for Healthcare Research and Quality. Medical Expenditure Panel Survey (MEPS) HC-089 Documentation, Year 2004. http://www.meps.ahrq.govAccessed August 1, 2007
  10. Agency for Healthcare Research and Quality. Medical Expenditure Panel Survey (MEPS) HC-050 Documentation, Year 2003. http://www.meps.ahrq.gov/mepsweb/Accessed August 1, 2007
  11. Mousa HM, van den Berg MM, Caniano DA, Hogan M, Di Lorenzo C, Hayes J. Cecostomy in children with defecation disorders. Dig Dis Sci. 2006;51:154–160
  12. Rasquin A, Di Lorenzo C, Forbes D, Guiraldes E, Hyams JS, Staiano A, et al. Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology. 2006;130:1527–1537
  13. Del Giudice E, Staiano A, Capano G, Romano A, Florimonte L, Miele E, et al. Gastrointestinal manifestations in children with cerebral palsy. Brain Dev. 1999;21:307–311
  14. Loening-Baucke V. Constipation in early childhood: patient characteristics, treatment, and long-term follow-up. Gut. 1993;34:1400–1404
  15. Van den Berg MM, Van Rossum CH, de Lorijn F, Reitsma JB, Di Lorenzo C, Benninga MA. Functional constipation in infants: a follow-up study. J Pediatr. 2005;147:700–704

 There are no potential conflicts of interest, and no study sponsors were involved in this project.

PII: S0022-3476(08)00675-6

doi: 10.1016/j.jpeds.2008.07.060

The Journal of Pediatrics
Volume 154, Issue 2 , Pages 258-262 , February 2009

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