The Journal of Pediatrics
Volume 154, Issue 2 , Pages 253-257 , February 2009

Prospective Study of Etiologic Agents of Acute Gastroenteritis Outbreaks in Child Care Centers

  • Whitney H. Lyman, DVM

      Affiliations

    • Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, NC
    • ,
  • Joan F. Walsh, PhD

      Affiliations

    • Department of Maternal and Child Health, School of Public Health, University of North Carolina, Chapel Hill, NC
    • ,
  • Jonathan B. Kotch, MD

      Affiliations

    • Department of Maternal and Child Health, School of Public Health, University of North Carolina, Chapel Hill, NC
    • ,
  • David J. Weber, MD

      Affiliations

    • Division of Infectious Diseases, School of Medicine, University of North Carolina, Chapel Hill, NC
    • ,
  • Elizabeth Gunn, BS

      Affiliations

    • Department of Maternal and Child Health, School of Public Health, University of North Carolina, Chapel Hill, NC
    • ,
  • Jan Vinjé, PhD

      Affiliations

    • Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, NC
    • Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA
    • Corresponding Author InformationReprint requests: Jan Vinjé, PhD, Division of Viral Diseases, Centers for Disease Control and Prevention, Mailstop G-04, Atlanta, GA 30333

Received 30 January 2008 ,Revised 11 June 2008 ,Accepted 30 July 2008.

References 

  1. Parashar UD, Bresee JS, Glass RI. The global burden of diarrhoeal disease in children. Bull World Health Organ. 2003;81:236
  2. Kotch JB, Bryant D. Effects of day care on the health and development of children. Curr Opin Pediatr. 1990;2:883–894
  3. Bell DM, Gleiber DW, Mercer AA, Phifer R, Guinter RH, Cohen AJ, et al. Illness associated with child day care: a study of incidence and cost. Am J Public Health. 1989;79:479–484
  4. Akihara S, Phan TG, Nguyen TA, Hansman G, Okitsu S, Ushijima H. Existence of multiple outbreaks of viral gastroenteritis among infants in a day care center in Japan. Arch Virol. 2005;150:2061–2075
  5. Glass RI, Noel J, Ando T, Fankhauser R, Belliot G, Mounts A, et al. The epidemiology of enteric caliciviruses from humans: a reassessment using new diagnostics. J Infect Dis. 2000;181:254–261
  6. Glass RI, Bresee JS, Parashar UD, Holman RD, Gentsch JR. First rotavirus vaccines licensed: is there really a need?. Acta Paediatr Suppl. 1999;88:2–8
  7. Glass RI, Kilgore PE, Holman RC, Jin S, Smith JC, Woods PA, et al. The epidemiology of rotavirus in the United States: surveillance and estimates of disease burden. J Infect Dis. 1996;174:5–11
  8. Taylor MB, Marx FE, Grabow WO. Rotavirus, astrovirus and adenovirus associated with an outbreak of gastroenteritis in a South African child care centre. Epidemiol Infect. 1997;119:227–230
  9. Green KY. Caliciviridae: the noroviruses. In:  Knipe DE,  Howley PM editor. Fields Virology. 5th ed.. Philadelphia: Lippincott Williams & Wilkins; 2007;p. 949–979
  10. Pang XL, Joensuu J, Vesikari T. Human calicivirus-associated sporadic gastroenteritis in Finnish children less than two years of age followed prospectively during a rotavirus vaccine trial. Pediatr Infect Dis J. 1999;18:420–426
  11. Pang XL, Honma S, Nakata S. Human caliciviruses in acute gastroenteritis of young children in the community. J Infect Dis. 2000;181:S288–S294
  12. Matsui SM, Greenberg HB. Astroviruses. In:  Knipe DE,  Howley PM,  Griffin DE,  Lamb RA,  Martin MA,  Roizman B, et al. editor. Fields Virology. 4th ed.. Philadelphia: Lippincott Williams & Wilkins; 2001;p. 875–893
  13. de Jong JC, Bijlsma K, Wermenbol AG, Verweij-Uijterwaal MW, van der Avoort HG, Wood DJ, et al. Detection, typing and subtyping of enteric adenoviruses 40 and 41 from fecal samples and observation of changing incidences of infections with these types and subtypes. J Clin Microbiol. 1993;31:1562–1569
  14. Dennehy PH. Transmission of rotavirus and other enteric pathogens in the home. Pediatr Infect Dis J. 2000;19:103–105
  15. US Food and Drug Administration. Product Approval Information: Licensing Action. http://www.fda.gov/cber/products/rotamer020306.htm2006;Accessed January 15, 2007
  16. Centers for Disease Control and Prevention. CDC's Advisory Committee recommends new vaccine to prevent rotavirus. http://www.cdc.gov/nip/news/pr/pr_rotavirus_feb2006.htmAccessed January 15, 2007
  17. Jothikumar N, Lowther J, Henshilwood K, Lees DN, Hill VR, Vinjé J. Rapid and sensitive detection of noroviruses using TaqMan-based one-step RT-PCR assays and application to shellfish samples. Appl Environ Microbiol. 2005;71:1870–1875
  18. Kageyama T, Kojima S, Shinohara M, Uchida K, Fukushi S, Hoshino FB, et al. Broadly reactive and highly sensitive assay for Norwalk-like viruses based on real-time quantitative reverse-transcription PCR. J Clin Microbiol. 2003;41:1548–1557
  19. Jothikumar N, Cromeans TL, Hill VR, Lu X, Sobsey MD, Erdman DD. Quantitative real-time PCR assays for detection of human adenoviruses and identification of serotypes 40 and 41. Appl Environ Microbiol. 2005;71:3131–3136
  20. Kojima S, Kageyama T, Fukushi S, Hoshino FB, Shinohara M, Uchida K, et al. Genogroup-specific PCR primers for detection of Norwalk-like viruses. J Virol Methods. 2002;100:107–114
  21. Allard A, Girones R, Juto P, Wadell G. Polymerase chain reaction for detection of adenoviruses in stool samples. J Clin Microbiol. 1990;28:2659–2667
  22. Noel JS, Lee TW, Kurtz JB, Glass RI, Monroe SS. Typing of human astroviruses from clinical isolates by enzyme immunoassay and nucleotide sequencing. J Clin Microbiol. 1995;33:797–801
  23. Grinde B, Jonassen TO, Ushijima H. Sensitive detection of group A rotaviruses by immunomagnetic separation and reverse transcription-polymerase chain reaction. J Virol Methods. 1995;55:327-3
  24. Vinjé J, Deijl H, van der Heide R, Lewis D, Hedlund KO, Svensson L, et al. Molecular detection and epidemiology of Sapporo-like viruses. J Clin Microbiol. 2000;38:530–536
  25. Das BK, Gentsch JR, Cicirello HG, Woods PA, Gupta A, Ramachandran M, et al. Characterization of rotavirus strains from newborns in New Delhi, India. J Clin Microbiol. 1994;32:1820–1822
  26. Gentsch JR, Glass RI, Woods P, Gouvea V, Gorziglia M, Flores J, et al. Identification of group A rotavirus gene 4 types by polymerase chain reaction. J Clin Microbiol. 1992;30:1365–1373
  27. Cheesbrough JS, Green J, Gallimore CI, Wright PA, Brown DW. Widespread environmental contamination with Norwalk-like viruses (NLV) detected in a prolonged hotel outbreak of gastroenteritis. Epidemiol Infect. 2000;125:93–98
  28. Rosenfeldt V, Vesikari T, Pang XL, Zeng SQ, Tvede M, Paerregaard A. Viral etiology and incidence of acute gastroenteritis in young children attending day-care centers. Pediatr Infect Dis J. 2005;24:962–965
  29. Glass RI, Bresee J, Jiang B, Parashar U, Yee E, Gentsch J. Rotavirus and rotavirus vaccines. Adv Exp Med Biol. 2006;582:45–54
  30. Mounts AW, Ando T, Koopmans M, Bresee JS, Noel J, Glass RI. Cold weather seasonality of gastroenteritis associated with Norwalk-like viruses. J Infect Dis. 2000;181(Suppl 2):S284–S287

 Supported by the Thrasher Research Fund (grant 02821-5). The findings and conclusions in this article are those of the authors and do not necessarily represent the views of the funding agency or the Centers for Disease Control and Prevention. The authors declare no conflicts of interest, real or perceived.

PII: S0022-3476(08)00674-4

doi: 10.1016/j.jpeds.2008.07.057

The Journal of Pediatrics
Volume 154, Issue 2 , Pages 253-257 , February 2009

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