The Journal of Pediatrics
Volume 154, Issue 1 , Pages 96-100 , January 2009

Predictors of Response to Proton Pump Inhibitor Therapy among Children with Significant Esophageal Eosinophilia

  • Jason E. Dranove, MD

      Affiliations

    • Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Indiana University School of Medicine, Indianapolis, IN
    • Corresponding Author InformationReprint requests: Dr Jason Dranove, Pediatric Gastroenterology, Hepatology, and Nutrition, Indiana University School of Medicine, 702 Barnhill Drive, ROC 4210, Indianapolis, IN 46205
    • ,
  • Debra S. Horn, RN

      Affiliations

    • Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Indiana University School of Medicine, Indianapolis, IN
    • ,
  • Miriam A. Davis, BS

      Affiliations

    • Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Indiana University School of Medicine, Indianapolis, IN
    • ,
  • Kevin M. Kernek, MD

      Affiliations

    • Division of Pediatric Pathology, Indiana University School of Medicine, Indianapolis, IN
    • ,
  • Sandeep K. Gupta, MD

      Affiliations

    • Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Indiana University School of Medicine, Indianapolis, IN

Received 21 April 2008 ,Revised 16 June 2008 ,Accepted 18 July 2008.

References 

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  13. Rodrigo S, Gebran A, Oh D, DeMeester S, Hagen J, Lipham J, et al. High intraepithelial eosinophil counts in esophageal squamous epithelium are not specific for eosinophilic esophagitis. Am J Gastroenterol. 2008;103:435–442
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  16. Rudolph CD, Mazur LJ, Liptak GS, Baker RD, Boyle JT, Colletti RB, et al. Guidelines for evaluation and treatment of gastroesophageal reflux in infants and children: recommendations of the North American Society for Pediatric Gastroenterology and Nutrition. J Pediatr Gastroenterol and Nutr. 2001;32:S1–S31
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  18. Orenstein SR, Shalaby TM, Di Lorenzo C, Putnam PE, Sigurdsson L, Kocoshis S. The spectrum of pediatric eosinophilic esophagitis beyond infancy: a clinical series of 30 children. Am J Gastroenterol. 2000;95:1422–1430
  19. Morrow JB, Vargo JJ, Goldblum JR, Richter JE. The ringed esophagus: histological features of GERD. Am J Gastroenterol. 2001;96:984–989
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  21. Remedios M, Campbell C, Jones DM, Kerlin P. Eosinophilic esophagitis in adults: clinical, endoscopic histologic findings, and response to treatment with fluticasone propionate. Gastrointest Endosc. 2006;63:3–12
  22. Liacouras CA, Spergel JM, Ruchelli E, Verma R, Mascarenhas M, Semeao E, et al. Eosinophilic esophagitis: a 10-year experience in 381 children. Clin Gastroenterol Hepatol. 2005;3:1198–1206
  23. Gupta SK, Fitzgerald JF, Chong SK, Croffie JM, Collins MH. Vertical lines in distal esophageal mucosa (VLEM): a true endoscopic manifestation of esophagitis in children?. Gastrointest Endosc. 1997;45:485–489
  24. Lim JR, Gupta SK, Croffie JM, Pfefferkorn MD, Molleston JP, Corkins MR, et al. White specks in the esophageal mucosa: an endoscopic manifestation of non-reflux eosinophilic esophagitis in children. Gastrointest Endosc. 2004;59:835–838
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 The authors declare no conflicts of interest or grant support.

PII: S0022-3476(08)00605-7

doi: 10.1016/j.jpeds.2008.07.042

The Journal of Pediatrics
Volume 154, Issue 1 , Pages 96-100 , January 2009

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