The Journal of Pediatrics
Volume 154, Issue 1 , Pages 132-134 , January 2009

Significant Vitamin D Deficiency in Youth with Type 1 Diabetes Mellitus

  • Britta M. Svoren, MD

      Affiliations

    • Pediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Boston, MA
    • Division of Endocrinology, Department of Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA
    • Corresponding Author InformationReprint requests: Britta Svoren, MD, Pediatric, Adolescent, and Young Adult Section, Joslin Diabetes Center, One Joslin Pl, Boston, MA 02215
    • ,
  • Lisa K. Volkening, MA

      Affiliations

    • Pediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Boston, MA
    • ,
  • Jamie R. Wood, MD

      Affiliations

    • Pediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Boston, MA
    • Division of Endocrinology, Department of Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA
    • ,
  • Lori M.B. Laffel, MD, MPH

      Affiliations

    • Pediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Boston, MA
    • Division of Endocrinology, Department of Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA

Received 27 March 2008 ,Revised 6 May 2008 ,Accepted 14 July 2008.

  • Image Result

    A, Vitamin D status. Among 0- to 5-, 6- to 11-, and 12- to 18-year-old children, the percentage of participants with either vitamin D insufficiency or deficiency was 56%, 69%, and 85%, respectively. B

    A, Vitamin D status. Among 0- to 5-, 6- to 11-, and 12- to 18-year-old children, the percentage of participants with either vitamin D insufficiency or deficiency was 56%, 69%, and 85%, respectively. B, Adjusted 25OHD levels. A mean adjusted 25OHD value was calculated for each age group, controlling for patient ethnicity, visit season, sex, z-BMI, A1c, and diabetes duration. The 12- to 18-year-old children had significantly lower 25OHD levels compared with the 0- to 5-year-old children (<0.01).

 Supported by grants from the National Institutes of Health (RO1DK046887 to L.L. and K12DK63696 to B.S.). Support was also received from the Charles H. Hood Foundation and Eli Lilly and Company. The authors declare no affiliations, financial agreements, or other involvements that would constitute a conflict of interest.

PII: S0022-3476(08)00597-0

doi: 10.1016/j.jpeds.2008.07.015

The Journal of Pediatrics
Volume 154, Issue 1 , Pages 132-134 , January 2009

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