The Journal of Pediatrics
Volume 154, Issue 1 , Pages 132-134, January 2009

Significant Vitamin D Deficiency in Youth with Type 1 Diabetes Mellitus

  • Britta M. Svoren, MD

      Affiliations

    • Pediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Boston, MA
    • Division of Endocrinology, Department of Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA
    • Corresponding Author InformationReprint requests: Britta Svoren, MD, Pediatric, Adolescent, and Young Adult Section, Joslin Diabetes Center, One Joslin Pl, Boston, MA 02215
    • ,
  • Lisa K. Volkening, MA

      Affiliations

    • Pediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Boston, MA
    • ,
  • Jamie R. Wood, MD

      Affiliations

    • Pediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Boston, MA
    • Division of Endocrinology, Department of Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA
    • ,
  • Lori M.B. Laffel, MD, MPH

      Affiliations

    • Pediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Boston, MA
    • Division of Endocrinology, Department of Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA

Received 27 March 2008; received in revised form 6 May 2008; accepted 14 July 2008.

Serum 25-hydroxyvitamin D was measured in 128 youth with type 1 diabetes mellitus. Less than 25% of the patients were vitamin D sufficient. Because individuals with type 1 diabetes mellitus possess multiple risk factors for skeletal fragility, ensuring vitamin D sufficiency throughout childhood and adolescence in this population seems especially warranted.

Abbreviations: 25OHD, 25-hydroxyvitamin D, A1c, Hemoglobin A1c, BMD, Bone mineral density, BMI, Body mass index, T1D, Type 1 diabetes mellitus

 

 Supported by grants from the National Institutes of Health (RO1DK046887 to L.L. and K12DK63696 to B.S.). Support was also received from the Charles H. Hood Foundation and Eli Lilly and Company. The authors declare no affiliations, financial agreements, or other involvements that would constitute a conflict of interest.

PII: S0022-3476(08)00597-0

doi:10.1016/j.jpeds.2008.07.015

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The Journal of Pediatrics
Volume 154, Issue 1 , Pages 132-134, January 2009

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