The Journal of Pediatrics
Volume 153, Issue 6 , Pages 777-782.e1, December 2008

Trends in Healthcare Usage Attributable to Diarrhea, 1995-2004

  • Stephen J. Pont, MD, MPH

      Affiliations

    • Department of Pediatrics, Vanderbilt University, Nashville, TN
  • ,
  • L. Rand Carpenter, DVM

      Affiliations

    • Tennessee Department of Health, Nashville, TN
    • Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA
  • ,
  • Marie R. Griffin, MD, MPH

      Affiliations

    • Department of Preventive Medicine, Vanderbilt University, Nashville, TN
  • ,
  • Timothy F. Jones, MD

      Affiliations

    • Tennessee Department of Health, Nashville, TN
  • ,
  • William Schaffner, MD

      Affiliations

    • Department of Preventive Medicine, Vanderbilt University, Nashville, TN
  • ,
  • Judith A. Dudley

      Affiliations

    • Department of Preventive Medicine, Vanderbilt University, Nashville, TN
  • ,
  • Patrick G. Arbogast, PhD

      Affiliations

    • Department of Preventive Medicine, Vanderbilt University, Nashville, TN
    • Department of Biostatistics, Vanderbilt University, Nashville, TN
  • ,
  • William O. Cooper, MD, MPH

      Affiliations

    • Department of Pediatrics, Vanderbilt University, Nashville, TN

Received 13 October 2007; received in revised form 29 April 2008; accepted 23 June 2008. published online 11 August 2008.

Objective

To determine current diarrhea-associated healthcare usage rates and associated sociodemographic factors. These data can be used to determine the impact of the rotavirus vaccine.

Study design

Using discharge diagnosis codes, we determined diarrhea-associated visit rates for children aged 0 to 18 years enrolled in Tennessee Medicaid, 1995-2004. Poisson regression compared data across time and within strata. The winter residual excess method estimated the rotavirus burden.

Results

Analyzing approximately 500 000 person-years annually, outpatient and hospitalization rates remained stable from 1995 to 2004; emergency department (ED) rates approximately doubled, incidence rate ratio (IRR): 1.92 (1.81-2.04). White children used healthcare at greater rates than black children: outpatient IRR 1.90: (1.85-1.95), ED IRR: 1.69 (1.64-1.74), and inpatient IRR: 1.82 (1.73-1.92); and rural children greater than urban: outpatient IRR 1.66 (1.62-1.70), ED IRR 1.14 (1.11-1.17), inpatient IRR 1.88 (1.80-1.97). Children aged 0 to 35 months experienced 1627 outpatient and 792 ED visits, and 148 hospitalizations per 10 000 child-years; rotavirus may have affected up to 40% of these hospitalizations.

Conclusions

Diarrhea-associated ED visit rates nearly doubled from 1995 to 2004. Future studies could explore factors resulting in increased healthcare usage by white children and those living in rural areas and document the rotavirus vaccine's impact after its release.

Abbreviations: 95% CI, 95% confidence interval, ED, Emergency department, ICD-9-CM, International Classification of Disease 9th Revision Clinical Modification, IRR, Incidence rate ratio, SMSA, Standard metropolitan statistical area

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 This study was supported by a National Institutes of Health National Research Service Award Grant, 5T32 HS013833-03 and by the Tennessee Department of Health, through the use of the TennCare data files. The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention. The authors declare no conflicts of interest relating to this work.

 No reprints.

PII: S0022-3476(08)00569-6

doi:10.1016/j.jpeds.2008.06.037

Refers to article:

  • Epidemiological Shifts in Severe Acute Gastroenteritis in US Children: Will Rotavirus Vaccination Change the Picture?

    Daniel C. Payne, Umesh D. Parashar
    The Journal of Pediatrics December 2008 (Vol. 153, Issue 6, Pages 737-738)

The Journal of Pediatrics
Volume 153, Issue 6 , Pages 777-782.e1, December 2008