The Journal of Pediatrics
Volume 153, Issue 3 , Pages 303-304 , September 2008

Autoimmunity and Minocycline

  • Terry L. Moore, MD

      Affiliations

    • Corresponding Author InformationReprint requests: Terry L. Moore, MD, Professor of Internal Medicine, Pediatrics, and Molecular Microbiology and Immunology, Director, Division of Rheumatology and Pediatric Rheumatology, Saint Louis University School of Medicine, 1402 S Grand Blvd, Room 211A Doisy Hall, St. Louis, MO 63104

References 

  1. Mongey AB, Hess EV. Drug insight: autoimmune effects of medications—what's new?. Nat Clin Rheumatol. 2008;4:136–144
  2. Burlingame RW, Rubin RL. Drug-induced anti-histone autoantibodies display two patterns of reactivity with substructures of chromatin. J Clin Invest. 1991;88:680–690
  3. Lawson TM, Amos N, Bulger D, Williams BD. Minocycline-induced lupus: clinical features and response to rechallenge. Rheumatology (Oxford). 2001;40:329–335
  4. El-Hallak M, Giani T, Yeniay BS, Jacobs KE, Kim S, Sundel RP, et al. Chronic minocycline induced autoimmunity in children. J Pediatr. 2008;153:314–319
  5. Eichenfield AH. Minocyline and autoimmunity. Curr Opin Pediatr. 1999;11:447–456
  6. Sturkenboom MCJM, Meier CR, Jick H, Strickler BHC. Minocycline and lupus like syndrome in acne patients. Arch Intern Med. 1999;159:484–490
  7. Tournigand C, Genereau T, Prudent M, Piermord MC, Hernson S, Chosidow O. Minocyline-induced clinical and biological lupus-like disease. Lupus. 1999;8:773–774
  8. Elkayam O, Levartovsky D, Brautbon C, Yaron M, Burke M, Vardinon N, et al. Clinical and immunological study of 7 patients with minocycline-induced autoimmune phenomena. Am J Med. 1998;105:484–487
  9. Dunphy J, Oliver M, Rands Al, Lovell CR, McHugh NJ. Anti-neutrophil cytoplasmic antibodies and HLA class II alleles in minocycline-induced lupus-like syndrome. Br J Dermatol. 2000;142:461–467

PII: S0022-3476(08)00395-8

doi: 10.1016/j.jpeds.2008.05.011

The Journal of Pediatrics
Volume 153, Issue 3 , Pages 303-304 , September 2008

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