The Journal of Pediatrics
Volume 153, Issue 4 , Pages 454-455 , October 2008

The Growing Skeleton is a Busy Place—Can Biochemical Bone Markers Keep Track of the Action?

  • Frank Rauch, MD

      Affiliations

    • Corresponding Author InformationReprint requests: Frank Rauch, Genetics Unit, Shriners Hospital for Children, 1529 Cedar Ave, Montréal, Québec H3G 1A6, Canada

References 

  1. Rauch F. Watching bone cells at work: what we can see from bone biopsies. Pediatr Nephrol. 2006;21:457–462
  2. Szulc P, Seeman E, Delmas PD. Biochemical measurements of bone turnover in children and adolescents. Osteoporos Int. 2000;11:281–294
  3. Seibel MJ. Biochemical markers of bone remodeling. Endocrinol Metab Clin North Am. 2003;32:83–113
  4. Tuchman S, Thayu M, Shults J, Zemel BS, Burnham JM, Leonard MB. Interpretation of biomarkers of bone metabolism in children: impact of growth velocity and body size in healthy children and chronic disease. J Pediatr. 2008;153:484–490
  5. Schonau E, Westermann F, Rauch F, Stabrey A, Wassmer G, Keller E, et al. A new and accurate prediction model for growth response to growth hormone treatment in children with growth hormone deficiency. Eur J Endocrinol. 2001;144:13–20
  6. Siffledeen JS, Siminoski K, Jen H, Fedorak RN. Vertebral fractures and role of low bone mineral density in Crohn's disease. Clin Gastroenterol Hepatol. 2007;5:721–728
  7. Semeao EJ, Stallings VA, Peck SN, Piccoli DA. Vertebral compression fractures in pediatric patients with Crohn's disease. Gastroenterology. 1997;112:1710–1713
  8. Persad R, Jaffer I, Issenman RM. The prevalence of long bone fractures in pediatric inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2006;43:597–602

PII: S0022-3476(08)00394-6

doi: 10.1016/j.jpeds.2008.05.010

The Journal of Pediatrics
Volume 153, Issue 4 , Pages 454-455 , October 2008

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