The Journal of Pediatrics
Volume 153, Issue 3 , Pages 305-307 , September 2008

Blame Vaccine Interference, Not Neonatal Immunization, for Suboptimal Responses after Neonatal Diphtheria, Tetanus, and Acellular Pertussis Immunization

  • Claire-Anne Siegrist, Prof

      Affiliations

    • Corresponding Author InformationReprint requests: Dr. Claire-Anne Siegrist, University of Geneva, Center for Vaccinolgy and Neonatal Immunology, CMU, 1, 1 Michel Servet, 1211 Geneva, Switzerland

References 

  1. Mooi FR, de Greeff SC. The case for maternal vaccination against pertussis. Lancet Infect Dis. 2007;7:614–624
  2. Halasa B, O'Shea A, Shi JR, LaFleur BJ, Edwards KM. Poor immune responses to a birth dose of diphtheria, tetanus, and acellular pertussis vaccine. J Pediatr. 2008;153:327–332
  3. Belloni C, De Silvestri A, Tinelli C, Avanzini MA, Marconi M, Strano F, et al. Immunogenicity of a three-component acellular pertussis vaccine administered at birth. Pediatrics. 2003;111(Pt 1):1042–1045
  4. Knuf M, Schmitt HJ, Wolter J, Schuerman L, Jacquet JM, Kieninger D, et al. Neonatal vaccination with an acellular pertussis vaccine accelerates the acquisition of pertussis antibodies in infants. J Pediatr. 2008;152:655–660
  5. McIntyre P, Wood N, Marshall H, Roberton D. Immunogenicity of birth and one month old acellular pertussis (Pa) vaccine. 47th ICAAC. Chicago 17-20 September 2007.
  6. Siegrist CA. Mechanisms by which maternal antibodies influence infant vaccine responses: review of hypotheses and definition of main determinants. Vaccine. 2003;21:3406–3412
  7. Siegrist CA. Vaccine Potentiation or Interference: How Much Do We Understand? 47th ICAAC. Chicago, 17-20 September 2007.
  8. Ota MO, Vekemans J, Schlegel-Haueter SE, Fielding K, Sanneh M, Kidd M, et al. Influence of Mycobacterium bovis bacillus Calmette-Guerin on antibody and cytokine responses to human neonatal vaccination. J Immunol. 2002;168:919–925
  9. Dagan R, Goldblatt D, Maleckar JR, Yaich M, Eskola J. Reduction of antibody response to an 11-valent pneumococcal vaccine coadministered with a vaccine containing acellular pertussis components. Infect Immun. 2004;72:5383–5391
  10. O'Brien KL, Hochman M, Goldblatt D. Combined schedules of pneumococcal conjugate and polysaccharide vaccines: is hyporesponsiveness an issue?. Lancet Infect Dis. 2007;7:597–606
  11. Roduit C, Bozzotti P, Mielcarek N, Lambert PH, del Giudice G, Locht C, et al. Immunogenicity and protective efficacy of neonatal vaccination against Bordetella pertussis in a murine model: evidence for early control of pertussis. Infect Immun. 2002;70:3521–3528
  12. Peeters CC, Tenbergen-Meekes AM, Poolman JT, Beurret M, Zegers BJ, Rijkers GT. Effect of carrier priming on immunogenicity of saccharide-protein conjugate vaccines. Infect Immun. 1991;59:3504–3510
  13. Dagan R, Poolman JT, Zepp F. Combination vaccines containing DTPa-Hib: impact of IPV and coadministration of CRM197 conjugates. Expert Rev Vaccines. 2008;7:97–115
  14. Denoel P, Poolman J, Carletti G, Veitch K. Effects of adsorption of acellular pertussis antigens onto different aluminum salts on the protective activity in an intranasal murine model of Bordetella pertussis infection. Vaccine. 2002;20:2551–2555

PII: S0022-3476(08)00309-0

doi: 10.1016/j.jpeds.2008.04.032

The Journal of Pediatrics
Volume 153, Issue 3 , Pages 305-307 , September 2008

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