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Volume 153, Issue 3, Pages 414-419.e1 (September 2008)


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Cigarette Smoking Associated with Attention Deficit Hyperactivity Disorder

Timothy E. Wilens, MDaCorresponding Author Informationemail address, Michael Vitulano, BAa, Himanshu Upadhyaya, MDb, Joel Adamson, BAa, Robert Sawtelle, BAa, Linsey Utzinger, BAa, Joseph Biederman, MDa

Received 14 November 2007; received in revised form 6 February 2008; accepted 4 April 2008. published online 06 June 2008.

Objective

To evaluate the association between attention deficit hyperactivity disorder (ADHD) and severity of physical dependence on nicotine in a controlled study of adolescents and young adults with ADHD.

Study design

In controlled longitudinal family studies of ADHD, we examined self-reports on the modified Fagerström Tolerance Questionnaire (mFTQ) for degrees of physical dependence on nicotine.

Results

We obtained mFTQ data from 80 ADHD probands and 86 control probands (mean age, 19.2 years). The smokers with ADHD had significantly higher scores on the mFTQ, indicative of more severe physical dependence on nicotine. Similarly, in current smokers, a positive linear relationship was found between mFTQ score and both inattentive and hyperactive ADHD symptoms. Environmental factors, such as current parental smoking, peer smoking, and living with a smoker, all increased the risk for smoking in those with ADHD compared with controls.

Conclusion

Male and female smokers with ADHD manifest more severe physical dependence on smoking compared with controls. Important environmental factors appear to add to the risk of smoking associated with ADHD.

a Pediatric Psychopharmacology Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA

b Department of Psychiatry, Medical University of South Carolina, Charleston, SC

Corresponding Author InformationReprint requests: Timothy E. Wilens, MD, Pediatric Psychopharmacology Unit, 55 Parkman Street, YAW 6A, Boston, MA 02114

 Supported in part by the National Institute on Drug Abuse (grants R01 DA14419, DA016264, and 5U10DA015831).

 Potential conflict of interest information is available at www.jpeds.com.

PII: S0022-3476(08)00296-5

doi:10.1016/j.jpeds.2008.04.030


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