The Journal of Pediatrics
Volume 153, Issue 3 , Page 319 , September 2008

50 Years Ago in The Journal of Pediatrics: Studies on the pH of the respiratory tract, i: endotracheal aspirate of the healthy newborn infants

  • Dennis W. Nielson, MD

      Affiliations

    • Pulmonary Division, Department of Pediatrics, University of California San Francisco, San Francisco, California
    • ,
  • Richard D. Bland, MD

      Affiliations

    • Vera Moulton Wall Cardiopulmonary Center, Department of Pediatrics, Stanford University School of Medicine, Stanford, California

References 

  1. Paget-Brown AO, Hunt JF, Gaston B. Tracheal aspirate pH is alkaline in pre-term human infants. Eur Respir J. 2007;30:840–842
  2. McShane D, Davies JC, Davies MG, Bush A, Geddes DM, Alton EWFW. Airway surface pH in subjects with cystic fibrosis. Eur Respir J. 2003;21:37–42
  3. Inglis SK, Wilson SM, Olver RE. Secretion of acid and base equivalents by intact distal airways. Am J Physiol Lung Cell Mol Physiol. 2003;284:L855–L862
  4. Quinton PM. The neglected ion: HCO3−. Nature Med. 2001;7:292–293
  5. Coakley RD, Grubb BR, Paradiso AM, Gatzy JT, Johnson LG, Kreda SM, et al. Abnormal surface liquid pH regulation by cultured cystic fibrosis bronchial epithelium. Proc Natl Natl Acad Sci U S A. 2003;100:16083–16088
  6. Song Y, Salinas D, Nielson DW, Verkman AS. Hyperacidity of secreted fluid from submucosal glands in early cystic fibrosis. Am J Physiol Cell Physiol. 2006;290:C741–C749

PII: S0022-3476(08)00230-8

doi: 10.1016/j.jpeds.2008.03.039

The Journal of Pediatrics
Volume 153, Issue 3 , Page 319 , September 2008

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