The Journal of Pediatrics
Volume 153, Issue 3 , Pages 396-401.e1 , September 2008

Longitudinal Follow-up of Bronchial Inflammation, Respiratory Symptoms, and Pulmonary Function in Adolescents after Repair of Esophageal Atresia with Tracheoesophageal Fistula

  • Kristiina Malmström, MD, PhD

      Affiliations

    • From the Department of Allergy, Helsinki University Central Hospital, Helsinki, Finland
    • Corresponding Author InformationReprint requests: Kristiina Malmström, MD, PhD, Department of Allergy, Helsinki University Central Hospital, PO Box 160, FI-00029 Helsinki, Finland
    • ,
  • Jouko Lohi, MD, PhD

      Affiliations

    • Department of Pathology, Helsinki University Central Hospital, Helsinki, Finland
    • ,
  • Harry Lindahl, MD, PhD

      Affiliations

    • Hospital for Children and Adolescents, Helsinki University Central Hospital, Helsinki, Finland
    • ,
  • Anna Pelkonen, MD, PhD

      Affiliations

    • From the Department of Allergy, Helsinki University Central Hospital, Helsinki, Finland
    • ,
  • Merja Kajosaari, MD, PhD

      Affiliations

    • Hospital for Children and Adolescents, Helsinki University Central Hospital, Helsinki, Finland
    • ,
  • Seppo Sarna, MD, PhD

      Affiliations

    • Department of Public Health, University of Helsinki, Finland
    • ,
  • L. Pekka Malmberg, MD, PhD

      Affiliations

    • From the Department of Allergy, Helsinki University Central Hospital, Helsinki, Finland
    • ,
  • Mika J. Mäkelä, MD, PhD

      Affiliations

    • From the Department of Allergy, Helsinki University Central Hospital, Helsinki, Finland

Received 23 November 2007 ,Revised 15 January 2008 ,Accepted 19 March 2008.

References 

  1. Spitz L. Oesophageal atresia. Orphanet J Rare Dis. 2007;11:24
  2. Chittmittrapap S, Spitz L, Kiely EM, Brereton RJ. Oesophageal atresia and associated anomalies. Arch Dis Child. 1989;64:364–368
  3. Delius RE, Wheatley MJ, Coran AG. Etiology and management of respiratory complications after repair of esophageal atresia with tracheoesophageal fistula. Surgery. 1992;112:527–532
  4. Chetcuti P, Myers NA, Phelan PD, Beasley SW. Adults who survived repair of congenital esophageal atresia and tracheoesophageal fistula. Br Med J. 1998;297:344–346
  5. Robertson DF, Mobaireek K, Davis GM, Coates AL. Late pulmonary function following repair of tracheoesophageal fistula or esophageal atresia. Pediatr Pulmonol. 1995;20:21–26
  6. Chetcuti P, Phelan PD. Respiratory morbidity after repair of oesophageal atresia and tracheo-oesophageal fistula. Arch Dis Child. 1993;68:167–170
  7. Milligan DW, Levison H. Lung function in children following repair of tracheoesophageal fistula. J Pediatr. 1979;95:24–27
  8. Agrawal L, Beardsmore CS, MacFadyen UM. Respiratory function in childhood following repair of oesophageal atresia and tracheoesophageal fistula. Arch Dis Child. 1999;81:404–408
  9. Chetcuti P, Phelan PD, Greenwood R. Lung function abnormalities in repaired oesophageal atresia and tracheo-oesophageal fistula. Thorax. 1992;47:1030–1034
  10. Biller JA, Allen JL, Schuster SR, Treves ST, Winter HS. Long-term evaluation of esophageal and pulmonary function in patients with repaired esophageal atresia and tracheoesophageal fistula. Dig Dis Sci. 1987;32:985–990
  11. Kovesi T, Rubin S. Long-term complications of congenital esophageal atresia and/or tracheoesophageal fistula. Chest. 2004;126:915–925
  12. Couriel JM, Hibbert M, Olinsky A, Phelan PD. Long term pulmonary consequences of oesophageal atresia with tracheo-oesophageal fistula. Acta Paediatr Scand. 1982;71:973–978
  13. Jeffery PK. Remodeling and inflammation of bronchi in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2004;1:176–183
  14. Lindahl H, Rintala R, Sariola H. Chronic esophagitis and gastric metaplasia are frequent late complications of esophageal atresia. J Pediatr Surg. 1993;28:1178–1180
  15. Schalamon J, Lindahl H, Saarikoski H, Rintala RJ. Endoscopic follow-up in esophageal atresia—for how long is it necessary?. J Pediatr Surg. 2003;38:702–704
  16. Pekkanen J, Remes ST, Husman T, Lindberg M, Kajosaari M, Koivikko A, et al. Prevalence of asthma symptoms in video and written questionnaires among children in four regions of Finland. Eur Respir J. 1997;10:1787–1794
  17. The American Thoracic SocietyThe Medical Section of the American Lung Association. Recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children—1999. Am J Respir Crit Care Med. 1999;160:2104–2117
  18. Malmberg LP, Petäys T, Haahtela T, Laatikainen T, Jousilahti P, Vartiainen E, et al. Exhaled nitric oxide in healthy nonatopic school-aged children—determinants and height-adjusted reference values. Pediatr Pulmonol. 2006;41:635–642
  19. Koillinen H, Wanne O, Niemi V, Laakkonen E. Reference values for spirometry and peak expiratory flow in healthy Finnish children. Finn Med J. 1998;53:395–402
  20. Sovijärvi ARA, Malmberg LP, Reinikainen K, Rytilä P, Poppius H. A rapid dosimetric with controlled tidal breathing for histamine challenge. Chest. 1993;104:164–170
  21. Filler RM, Messineo A, Vinogard I. Severe tracheomalacia associated with esophageal atresia: results of surgical treatment. J Pediatr Surg. 1992;27:1136–1141
  22. Cook HC. Manual of histological demonstration techniques. London, UK: Butterworths; 1974;
  23. Somppi E, Tammela O, Ruuska T, Rahnasto J, Laitinen J, Turjanmaa V, et al. Outcome of patients operated on for esophageal atresia: 30 years' experience. J Pediatr Surg. 1998;33:1341–1346
  24. LeSouëf P, Myers NA, Landau LI. Etiologic factors in long-term respiratory function abnormalities following esophageal atresia repair. J Pediatr Surg. 1987;22:918–922
  25. von Hertzen L, Mäkelä MJ, Petäys T, Jousilahti P, Kosunen TU, Laatikainen T, et al. Growing disparities in atopy between the Finns and the Russians: a comparison of 2 generations. J Allergy Clin Immunol. 2006;117:151–157
  26. Taylor DR, Pijnenburg MW, Smith AD, De Jongste JC. Exhaled nitric oxide measurements: clinical application and interpretation. Thorax. 2006;61:817–827
  27. Baraldi E, Bontto G, Zacchello F, Filippone M. Low exhaled nitric oxide in school-age children with bronchopulmonary dysplasia and airflow limitation. Am J Respir Crit Care Med. 2005;171:68–72
  28. Holgate ST, Holloway J, Wilson S, Bucchieri F, Puddicombe S, Davies DE. Epithelial-mesenchymal communication in the pathogenesis of chronic asthma. Proc Am Thorac Soc. 2004;1:93–98
  29. Guerra S, Martinez FD. Asthma genetics: from linear to multifactorial approaches. Annu Rev Med. 2008;59:199–213
  30. Saglani S, Nicholson AG, Scallan M, BaPFour-Lynn I, Rosenthal M. Investigation of your children with severe recurrent wheeze: any clinical benefit?. Eur Respir J. 2006;27:29–35
  31. Malmström K, Lindahl H, Mäkelä M. Usefulness of bronchoscopy in children: clinical or research tool?. http://www.eaaci.netdoi:10.1594/eaacinet2007/EO/2-080207.
  32. Bush A, Pohunek P. Brush biopsy and mucosal biopsy. Am J Respir Crit Care Med. 2000;162:S18–S22

 Supported by Finska Läkaresällskapet and Nummela Sanatorium Foundation.

PII: S0022-3476(08)00224-2

doi: 10.1016/j.jpeds.2008.03.034

The Journal of Pediatrics
Volume 153, Issue 3 , Pages 396-401.e1 , September 2008

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