The Journal of Pediatrics
Volume 153, Issue 1 , Pages 3-4 , July 2008

The Pathogenesis of Chorioamnionitis

  • Armond S. Goldman, MD

      Affiliations

    • Corresponding Author InformationReprint requests: Armond S. Goldman, MD, Emeritus Professor, Division of Infectious Diseases and Immunology, Section of Immunology/Allergy/Rheumatology, Department of Pediatrics, The Children's Hospital, The University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555-0369.
  • ,
  • Frank C. Schmalstieg, MD, PhD

References 

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  2. Aly H, Alhabashi G, Hammad TA, Owusu-Ansah S, Bathgate S, Mohamed M. ABO phenotype and risk factors associated with chorioamnionitis. J Pediatr. 2008;153:16–18
  3. Metchnikov E. The Nobel Prize in Physiology or Medicine 1908 (On the present state of the question of immunity in infectious diseases. December 11, 1908. Nobel Prize Organization). http://nobelprize.org/nobel_prizes/medicine/laureates/1908/Mechnikov-lecture.htmlAccessed Sep 6, 2007
  4. Ehrlich P. The Nobel Prize in Physiology or Medicine 1908 (Partial cell functions. December 11, 1908. Nobel Prize Organization). http://nobelprize.org/nobel_prizes/medicine/laureates/1908/ehrlich-lecture.htmlAccessed Sep 6, 2007
  5. Metchnikoff E. Leçon sur la pathologie comparée de l'inflammation. Paris: Masson; 1892;
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  8. Gravett MG, Adams KM, Sadowsky DW, Grosvenor AR, Witkin SS, Axthelm MK, et al. Immunomodulators plus antibiotics delay preterm delivery after experimental intraamniotic infection in a nonhuman primate model. Am J Obstet Gynecol. 2007;197:518;e1-8
  9. Holst RM, Laurini R, Jacobsson B, Samuelsson E, Sävman K, Doverhag C, et al. Expression of cytokines and chemokines in cervical and amniotic fluid: relationship to histological chorioamnionitis. J Matern Fetal Neonatal Med. 2007;20:885–893
  10. Sadowsky DW, Adams KM, Gravett MG, Witkin SS, Novy MJ. Preterm labor is induced by intraamniotic infusions of interleukin-1beta and tumor necrosis factor-alpha but not by interleukin-6 or interleukin-8 in a nonhuman primate model. Am J Obstet Gynecol. 2006;195:1578–1589
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  13. Ozaki M, Ogata M, Nandate K, Kawasaki T, Sata T. The effects of ethanol on beta2-integrin and l-selectin on the surface of leukocytes in human whole blood. J Trauma. 2007;63:770–774
  14. Gonzalez-Quintela A, Alende R, Gude F, Campos J, Rey J, Meijide LM, et al. Serum levels of immunoglobulins (IgG, IgA, IgM) in a general adult population and their relationship with alcohol consumption, smoking and common metabolic abnormalities. Clin Exp Immunol. 2008;151:42–50
  15. Harrison-Findik DD, Schafer D, Klein E, Timchenko NA, Kulaksiz H, Clemens D, et al. Alcohol metabolism-mediated oxidative stress down-regulates hepcidin transcription and leads to increased duodenal iron transporter expression. J Biol Chem. 2006;11:281:22974–82
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  18. Jurado RL. Iron, infections, and anemia of inflammation. Clin Infect Dis. 1997;25:888–895
  19. Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004;306:2090–2093
  20. Wrighting DM, Andrews NC. Interleukin-6 induces hepcidin expression through STAT3. Blood. 2006;108:3204–3209
  21. Schmalstieg FC, Goldman AS. The basis of susceptibility to lung infection. In:  Cagle P,  Fander DS,  Jagidr J,  Barrios R,  Haque A,  Popper H editor. Molecular pathology of lung disease. New York: Springer; 2008;p. 369–381

PII: S0022-3476(08)00222-9

doi: 10.1016/j.jpeds.2008.03.029

The Journal of Pediatrics
Volume 153, Issue 1 , Pages 3-4 , July 2008