The Journal of Pediatrics
Volume 153, Issue 2 , Pages 203-208.e4 , August 2008

The Influence of Gestational Age on Severity of Impairment in Spastic Cerebral Palsy

  • Karla Hemming, PhD

      Affiliations

    • Department of Statistics, University of Warwick, Coventry, UK
    • Corresponding Author InformationReprint requests: Karla Hemming, PhD, Department of Statistics, University of Warwick, Gibbett Hill Road, Coventry CV5 7AL, UK.
    • ,
  • Allan Colver, MD

      Affiliations

    • School of Clinical Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
    • ,
  • Jane L. Hutton, PhD

      Affiliations

    • Department of Statistics, University of Warwick, Coventry, UK
    • ,
  • Jennifer J. Kurinczuk, MD

      Affiliations

    • National Perinatal Epidemiology Unit, University of Oxford, Oxford, UK
    • ,
  • Peter O.D. Pharoah, MD

      Affiliations

    • Department of Public Health, University of Liverpool, Liverpool, UK.

Received 2 October 2007 ,Revised 4 February 2008 ,Accepted 22 February 2008.

References 

  1. Jarvis S, Glinianaia SV, Torrioli MG, Platt MJ, Miceli M, Jouk PS, et al. Cerebral palsy and intrauterine growth in single births: the European Collaborative Study. Lancet. 2003;362:1106–1111
  2. Glinianaia SV, Jarvis S, Topp M, Guillem P, Platt MJ, Pearce MS, et al. Intrauterine growth and cerebral palsy in twins: a European multicenter study. Twin Res Hum Genet. 2006;9:460–466
  3. Jarvis S, Glinianaia SV, Arnaud C, Fauconnier J, Johnson A, McManus V, et al. Case sex and severity in cerebral palsy varies with intrauterine growth. Arch Dis Child. 2005;90:474–479
  4. Jarvis S, Glinianaia SV, Blair E. Cerebral palsy and intrauterine growth. Clin Perinatol. 2006;33:285–300
  5. Blair E, Stanley F. Intrauterine growth and spastic cerebral palsy. Am J Obstet Gynecol. 1990;162:229–237
  6. Uvebrant P, Hagberg G. Intrauterine growth in children with cerebral palsy. Acta Paediatr. 1992;81:407–412
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  9. Hemming K, Hutton JL, Bonellie S, Kurinczuk JJ. Intrauterine growth and survival in cerebral palsy. Arch Dis Child Fetal Neonatal Ed. 2007;2:F121–F126
  10. Stanley F, Blair E, Alberman E. In: Cerebral Palsy: Epidemiology and Causal Pathways. MacKeith Press; 2000;p. 20
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  17. Cans C, Dolk H, Platt MJ, Colver A, Prasauskiene A, Krägeloh-Mann I. Recommendations from the SCPE collaborative group for defining and classifying cerebral palsy. Dev Med Child Neurol. 2007;109:35–38
  18. Hemming K, Hutton JL, Colver A, Platt MJ. Regional variation in survival of people with cerebral palsy in the United Kingdom. Pediatrics. 2005;116:1383–1390
  19. Surman G, Bonellie S, Chalmers J, Colver A, Dolk H, Hemming K, et al. UKCP: a collaborative network of cerebral palsy registers in the United Kingdom. J Public Health (Oxf). 2006;28:148–156
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  28. Hutton JL, Pharoah POD. Effect of cognitive, motor and sensory disabilities on survival in cerebral palsy. Arch Dis Child. 2002;86:84–89
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 Sources of funding available at www.jpeds.com.

 Information on conflicts of interest available at www.jpeds.com.

 Karla Hemming was employed as a research assistant to Jane Hutton and Peter Pharoah under Medical Research grant G9900630, “Life expectancy in children and young adults with cerebral palsy: A UK collaboration.” The merging and cleaning of the database also was funded by this grant. Jennifer Kurinczuk was partially funded by National Public Health Career Scientist award PHCS022 from the National Coordinating Centre for Research Capacity Development. The Merseyside and Cheshire register is currently funded by the National Health Service. The North of England Collaborative Cerebral Palsy Survey receives grants from the Directors of Public Health of the Northern and Yorkshire Region and Primary Health Care Trusts. The 4Child - Four Counties Database of Cerebral Palsy, Vision Loss and Hearing Loss in Children is currently funded by the Department of Health under the Research Active Disease Registers Initiative and is based at the National Perinatal Epidemiology Unit, which is funded by the Department of Health. The Scottish Register of Children with Motor Deficit of Central Origin was originally set up at Glasgow University and funded by a grant from the Chief Scientist of the Scottish Office. The register was subsequently transferred to the care of the Information Services Division of the National Health Service, National Services Scotland. The Northern Ireland Cerebral Palsy Register is funded by the Department of Health, Social Services and Public Safety.

 Jane Hutton and Peter Pharoah have acted as expert witnesses on life expectancy, for both plaintiffs and defendants, in medicolegal cases. The various funding sources had no involvement in the design, collection, analysis or interpretation of data, or the decision to submit for publication. The views expressed in this article are those of the authors and not necessarily those of the funding bodies. No author received any payment to produce the manuscript.

PII: S0022-3476(08)00177-7

doi: 10.1016/j.jpeds.2008.02.041

The Journal of Pediatrics
Volume 153, Issue 2 , Pages 203-208.e4 , August 2008

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