Hypoallergenicity and Effects on Growth and Tolerance of a New Amino Acid-Based Formula with Docosahexaenoic Acid and Arachidonic Acid

Study 1: Mean achieved weight of male subjects (A) and female subjects (B) from 14 to 120 days of age with CDC reference percentiles (3 to 97). The control group is represented as a solid line; the experimental group, as a dashed line.

Study 1: Plasma concentrations (μmol/L) of essential amino acids in the experimental and control groups (median) and in 1-month-old reference breast-fed infants (mean).²⁶ The breast-fed reference infants are represented as the white column; the experimental group, as the black column; and the control group, as the dashed column. *Significantly higher in the experimental group than in the control group (P < .05).

Study 2: History of allergic manifestations at study entry in the 29 subjects completing both challenges. Ongoing is represented as the dashed column; resolved, as the white column. Ongoing allergic manifestations were noted in 24 of 29 subjects at study entry. *Allergic GI manifestations included allergic enterocolitis, esophagitis and gastroesophageal reflux.