The Journal of Pediatrics
Volume 153, Issue 2 , Pages 254-261.e1 , August 2008

PEG3350 in the Treatment of Childhood Constipation: A Multicenter, Double-Blinded, Placebo-Controlled Trial

  • Samuel Nurko, MD

      Affiliations

    • Children's Hospital Boston, Boston, MA
    • Corresponding Author InformationReprint requests: Dr Samuel Nurko, Center for Motility and Functional Gastrointestinal Disorders, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115.
    • ,
  • Nader N. Youssef, MD

      Affiliations

    • Goryeb Children's Hospital, Morristown, NJ
    • ,
  • Mahmoud Sabri, MD

      Affiliations

    • Geisinger Medical Center, Danville, PA
    • ,
  • Annette Langseder, RN

      Affiliations

    • Goryeb Children's Hospital, Morristown, NJ
    • ,
  • John McGowan, BS

      Affiliations

    • Braintree Laboratories, Boston, MA
    • ,
  • Mark Cleveland, PhD

      Affiliations

    • Braintree Laboratories, Boston, MA
    • ,
  • Carlo Di Lorenzo, MD

      Affiliations

    • Nationwide Children's Hospital, Columbus, OH.

Received 7 July 2007 ,Revised 5 December 2007 ,Accepted 29 January 2008.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 30.00 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.

 Supported in part by Braintree Laboratories, Inc, and by grants MO1-RR02172 from NCRR NIH to Children's Hospital Boston GCRC and grant M01 RR 000084 to Children's Hospital of Pittsburgh.

 Conflict of Interest information available at www.jpeds.com.

 The protocol was originally designed by the principal investigator (Dr Nurko), and later modifications occurred with input from Drs DiLorenzo, Youssef, and Sabri. After the protocol was finalized, it was submitted to the sponsor, who agreed to fund the project and participated in some later modifications of the protocol design. The collection of the data was done by the investigators. The analysis of the data was done in a joint fashion between the investigators and the sponsor. The interpretation of the data was done by the investigators. The first draft of the manuscript was written by Dr Nurko, and there was no honorarium involved in the production of the manuscript. Later drafts were modified by the other investigators. The sponsors reviewed the manuscript but did not modify its main content, message, or conclusions. The decision to submit for publication and where to submit were done by the investigators, without any input form the sponsor. The results and publication were not influenced by the sponsor in any way.

PII: S0022-3476(08)00082-6

doi: 10.1016/j.jpeds.2008.01.039

The Journal of Pediatrics
Volume 153, Issue 2 , Pages 254-261.e1 , August 2008

Article Tools

* Image Usage & Resolution