The Journal of Pediatrics
Volume 153, Issue 1 , Pages 137-139 , July 2008

Inaccurate Hemoglobin A1C Levels in Patients with Type 1 Diabetes and Hereditary Persistence of Hemoglobin F

  • Eric I. Felner, MD

      Affiliations

    • Corresponding Author InformationReprint requests: Eric I. Felner, MD, Emory University School of Medicine, Department of Pediatrics, Division of Endocrinology, 2015 Uppergate Drive, Atlanta, GA 30322.
    • ,
  • Maureen McGrath, APRN-BC

Received 5 October 2007 ,Revised 27 December 2007 ,Accepted 18 January 2008.

References 

  1. Eckfield JH, Bruns DE. Another step toward standardization of methods for measuring hemoglobin A1C [editorial]. Clin Chem. 1997;43:1944–1951
  2. John WG. Glycated haemoglobin analysis. Ann Clin Biochem. 1997;34:17–31
  3. American Diabetes Association. Standards of medical care in diabetes. Diabetes Care. 2007;30(Suppl 1):S4–S41
  4. American Diabetes Association. Care of children and adolescents with type 1 diabetes. Diabetes Care. 2005;28:186–212
  5. Weykamp CW, Penders TJ, Siebelder CW, Muskiet FA, van der Slik W. Interference of carbamylated and acetylated hemoglobins in assays of glycohemoglobin by HPLC, electrophoresis, affinity chromatography, and enzyme immunoassay. Clin Chem. 1993;39:138–142
  6. Bry L, Chen PC, Sacks DB. Effects of hemoglobin variants and chemically modified derivatives on assays for glycohemoglobin. Clin Chem. 2001;47:153–163
  7. Ashley-Kock A, Yang Q, Olney RS. Sickle hemoglobin (Hb S) allele and sickle cell disease. Am J Genet. 2000;151:839–845
  8. Hoyer JD, Penz CS, Fairbanks VF, Hanson CA, Katzmann JA. Flow cytometric measurement of hemoglobin F in RBCs. Am J Clin Pathol. 2002;117:857–863
  9. Henney MM, Delgrosso K, Robinson R, Johnson CA, Daeschner CW, Campbell TA, et al. Interpretation of fetal hemoglobin only on newborn screening for hemoglobin. J Pediatr Hematol Oncol. 2002;24:499–502
  10. Puukka R, Puukka M. Effect of hemoglobin F on measurements of hemoglobin A1C with physicians' office analyzers. Clin Chem. 1994;40:342–343

PII: S0022-3476(08)00065-6

doi: 10.1016/j.jpeds.2008.01.024

The Journal of Pediatrics
Volume 153, Issue 1 , Pages 137-139 , July 2008

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