The Journal of Pediatrics
Volume 153, Issue 1 , Pages 137-139, July 2008

Inaccurate Hemoglobin A1C Levels in Patients with Type 1 Diabetes and Hereditary Persistence of Hemoglobin F

  • Eric I. Felner, MD

      Affiliations

    • Corresponding Author InformationReprint requests: Eric I. Felner, MD, Emory University School of Medicine, Department of Pediatrics, Division of Endocrinology, 2015 Uppergate Drive, Atlanta, GA 30322.
    • ,
  • Maureen McGrath, APRN-BC

Department of Pediatrics, Division of Endocrinology, Emory University School of Medicine, Atlanta, GA.

Received 5 October 2007; received in revised form 27 December 2007; accepted 18 January 2008.

We report 2 African-American boys with type 1 diabetes and hereditary persistence of hemoglobin F. The diagnosis came to light after both patients exhibited inconsistent hemoglobin A1C (HbA1C) levels with respect to serum glucose measurements. This demonstrates the importance of frequent glucose monitoring and interpreting the HbA1C level in light of serum glucose measurements.

Abbreviations: Hb, Hemoglobin, HbA1C, Hemoglobin A1C, HbAC, Hemoglobin C trait, HbAS, Hemoglobin S trait, HPHF, Hereditary persistence of hemoglobin F, HPLC, High-performance liquid chromatography, HS, Hereditary spherocytosis, SMBG, Self-monitored blood glucose, T1D, Type 1 diabetes

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PII: S0022-3476(08)00065-6

doi:10.1016/j.jpeds.2008.01.024

Refers to article:

  • Discordant HbA1c Results: The Hoofbeats Increase

    Robert M. Cohen, Clinton H. Joiner, Robert S. Franco
    The Journal of Pediatrics July 2008 (Vol. 153, Issue 1, Pages 7-9)

The Journal of Pediatrics
Volume 153, Issue 1 , Pages 137-139, July 2008

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