The Journal of Pediatrics
Volume 152, Issue 5 , Pages 603-604 , May 2008

A Boost to the Study of Insulin Secretion in Children and Adolescents

  • Kristen Nadeau, MD
    • ,
  • Philip S. Zeitler, MD, PhD

      Affiliations

    • Corresponding Author InformationReprint requests: Philip S. Zeitler, MD, PhD, Division of Endocrinology, The Children's Hospital, 13123 E 16th Ave, B265, Aurora, CO 80045.

References 

  1. Bacha F, Gungor N, Arslanian S. Measures of β-cell function during glucose tolerance test and liquid mixed-meal and the hyperglycemic clamp. J Pediatr. 2007;152:618–621
  2. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol. 1979;237:E214–E223
  3. Uwaifo GI, Fallon EM, Chin J, Elberg J, Parikh SJ, Yanovski JA. Indices of insulin action, disposal, and secretion derived from fasting samples and clamps in normal glucose-tolerant black and white children. Diabetes Care. 2002;25:2081–2087
  4. Hansen T, Drivsholm T, Urhammer SA, Palacios RT, Volund A, Borch-Johnsen K, et al. The BIGTT test: a novel test for simultaneous measurement of pancreatic β-cell function, insulin sensitivity, and glucose tolerance. Diabetes Care. 2007;30:257–262
  5. Mitrakou A, Vuorinen-Markkola H, Raptis G, Toft I, Mokan M, Strumph P, et al. Simultaneous assessment of insulin secretion and insulin sensitivity using a hyperglycemia clamp. J Clin Endocrinol Metab. 1992;75:379–382

PII: S0022-3476(08)00008-5

doi: 10.1016/j.jpeds.2008.01.005

The Journal of Pediatrics
Volume 152, Issue 5 , Pages 603-604 , May 2008

Article Tools