The Journal of Pediatrics
Volume 152, Issue 6 , Pages 761-765 , June 2008

First Day of Life Pulse Oximetry Screening to Detect Congenital Heart Defects

  • Alf Meberg, PhD

      Affiliations

    • Department of Paediatrics, Vestfold Hospital, Tønsberg, Norway
    • Corresponding Author InformationReprint requests: Alf Meberg MD, PhD, Department of Paediatrics, Vestfold Hospital, 3103 Tønsberg, Norway.
    • ,
  • Sabine Brügmann-Pieper, MD

      Affiliations

    • Department of Paediatrics, Buskerud Hospital, Drammen, Norway
    • ,
  • Reidar Due Jr, MD

      Affiliations

    • Department of Paediatrics, Bærum Hospital, Sandvika, Norway
    • ,
  • Leif Eskedal, MD

      Affiliations

    • Department of Paediatrics, Sørlandet Hospital, Kristiansand, Norway
    • ,
  • Ingebjørg Fagerli, MD

      Affiliations

    • Department of Paediatrics, Nordland Hospital, Bodø, Norway
    • ,
  • Teresa Farstad, PhD

      Affiliations

    • Department of Paediatrics, Akershus University Hospital, Nordbyhagen, Norway
    • ,
  • Dag Helge Frøisland, MD

      Affiliations

    • Department of Paediatrics, Innlandet Hospital, Lillehammer, Norway
    • ,
  • Catharina Hovland Sannes, MD

      Affiliations

    • Department of Paediatrics, Telemark Hospital, Skien, Norway
    • ,
  • Ole Jakob Johansen, MD

      Affiliations

    • Department of Paediatrics, St Olav Hospital, Trondheim, Norway
    • ,
  • Jasmina Keljalic, MD

      Affiliations

    • Department of Paediatrics, Sørlandet Hospital, Arendal, Norway
    • ,
  • Trond Markestad, PhD

      Affiliations

    • Department of Paediatrics, Innlandet Hospital, Gjøvik, Norway
    • ,
  • Egil Andre Nygaard, MD

      Affiliations

    • Department of Paediatrics, Østfold Hospital, Fredrikstad, Norway
    • ,
  • Alet Røsvik, MD

      Affiliations

    • Department of Paediatrics, Stavanger University Hospital, Stavanger, Norway
    • ,
  • Inger Elisabeth Silberg, MD

      Affiliations

    • Department of Paediatrics, The National Hospital, Oslo, Norway.

Received 26 September 2007 ,Revised 12 November 2007 ,Accepted 17 December 2007.

References 

  1. Wren C, Richmond S, Donaldson L. Presentation of congenital heart disease in infancy: implications for routine examination. Arch Dis Child Fetal Neonatal Ed. 1999;80:F49–F53
  2. Meberg A, Otterstad JE, Frøland G, Hals J, Sørland SJ. Early clinical screening of neonates for congenital heart defects: the cases we miss. Cardiol Young. 1999;9:169–174
  3. Mellander M, Sunnegårdh J. Failure to diagnose critical heart malformations in newborns before discharge—an increasing problem?. Acta Paediatr. 2006;95:407–413
  4. Reinhard Z, Wren C. Twenty year trends in recognition of life-threathening neonatal cardiac malformations. Cardiol Young. 2006;16:312
  5. Richmond S, Reay G, Abu Harb M. Routine pulse oximetry in the asymptomatic newborn. Arch Dis Child Fetal Neonatal Ed. 2002;87:F83–F88
  6. Hoke TR, Donohue PK, Bawa PK, Mitchell RD, Pathak A, Rowe PC, et al. Oxygen saturation as a screening test for critical congenital heart disease: a preliminary study. Pediatr Cardiol. 2002;23:403–409
  7. Koppel RI, Druschel CM, Carter T, Goldberg BE, Metha PN, Talwar R, et al. Effectiveness of pulse oximetry screening for congenital heart disease in asymptomatic newborns. Pediatrics. 2003;111:451–455
  8. Reich JD, Miller S, Brogdon B, Casatelli J, Gomph TC, Huhta JC, et al. The use of pulse oximetry to detect congenital heart disease. J Pediatr. 2003;142:268–272
  9. Bakr AF, Habib HS. Combining pulse oximetry and clinical examination in screening for congenital heart disease. Pediatr Cardiol. 2005;26:832–835
  10. Rosati E, Chitano G, Dipaola L, De Felice C, Latini G. Indications and limitations for a neonatal pulse oximetry screening of critical congenital heart disease. J Pediatr. 2005;33:455–457
  11. Arlettaz R, Bauschatz AS, Mönkhoff M, Essers B, Bauersfeld U. The contribution of pulse oximetry to the early detection of congenital heart disease in newborns. Eur J Pediatr. 2006;165:94–98
  12. Pass KA. Not as pink as you think!. Pediatrics. 2003;111:670–671
  13. Hannon DW. Relief for the (missed) blue babies. J Pediatr. 2003;142:231–233
  14. Valmari P. Should pulse oximetry be used to screen for congenital heart disease?. Arch Dis Child Fetal Neonatal Ed. 2007;92:219–224
  15. Thangaratinam S, Daniels J, Ewer AK, Zamora J, Khan KS. Accuracy of pulse oximetry in screening for congenital heart disease in asymptomatic newborns: a systematic review. Arch Dis Child Fetal Neonatal Ed. 2007;92:176–180
  16. Aamir T, Kruse L, Ezeakudo O. Delayed diagnosis of critical congenital cardiovascular malformations (CCVM) and pulse oximetry screening of newborns. Acta Paediatrica. 2007;96:1146–1149
  17. Kopotic RJ, Lindner W. Assessing high-risk infants in the delivery room with pulse oximetry. Anesth Analg. 2002;94:S31–S36
  18. Abu-Harb M, Hey E, Wren C. Death in infancy from unrecognized congenital heart disease. Arch Dis Child. 1994;71:3–7
  19. Tegnander E, Williams W, Johansen OJ, Blass H-GK, Eik-Nes S. Prenatal detction of heart defects in a non-selected population of 30,149 fetuses—detection rates and outcome. Ultrasound Obstet Gynecol. 2006;27:252–265
  20. Westin M, Saltvedt S, Bergman G, Kublickas M, Alström H, Grunewald C, et al. Routine ultrasound examination at 12 or 18 gestational weeks for prenatal detection of major congenital heart malformations? (A randomised controlled trial comprising 36 299 fetuses). BJOG. 2006;113:675–682
  21. Dawes GS. Foetal and neonatal physiology. Chicago: Year Book Medical Publishers; 1968;
  22. Meberg A, Brun C. Pulse oximetry screening for congenital heart defects in newborn infants. XIX Nordic Congress of Perinatal Medicine, Lund, Sweden, May 19-21, 2005 (abstract).
  23. Toth B, Becker A, Seelbach-Göbel B. Oxygen saturation in healthy newborn infants immediately after birth measured by pulse oximetry. Arch Gynecol Obstet. 2002;266:105–107
  24. Kamlin COF, O'Donnell CPF, Davis PG, Morley CJ. Oxygen saturation in healthy infants immediately after birth. J Pediatr. 2006;148:585–589
  25. Rabi Y, Yee W, Chen SY, Singhal N. Oxygen saturation trends immediately after birth. J Pediatr. 2006;148:590–594
  26. De-Wahl Granelli A, Mellander M, Sunnegårdh J, Sandberg K, Östman-Smith I. Screening for duct-dependent congenital heart disease with pulse oximetry: a critical evaluation of strategies to maximize sensitivity. Acta Paediatr. 2005;94:1590–1596

 Supported by grants from The Norwegian Society for Children with Heart Diseases, The Health Region South Trust, The Reneé and Bredo Grimsgaard Foundation, and Grethe Witzøe, Norway.

PII: S0022-3476(07)01187-0

doi: 10.1016/j.jpeds.2007.12.043

The Journal of Pediatrics
Volume 152, Issue 6 , Pages 761-765 , June 2008

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