The Journal of Pediatrics
Volume 152, Issue 4 , Pages 585-586 , April 2008

Performance of QuantiFERON-TB Testing in a Tuberculosis Outbreak at a Primary School

  • Paola Molicotti, PhD

      Affiliations

    • Department of Biomedical Science, University of Sassari, Sassari, Italy
    • Corresponding Author InformationReprint requests: Paola Molicotti, Department of Biomedical Sciences, University of Sassari, Viale San Pietro 43/b, 07100 Sassari, Italy.
  • ,
  • Alessandra Bua, PhD

      Affiliations

    • Department of Biomedical Science, University of Sassari, Sassari, Italy
  • ,
  • Graziella Mela, MD

      Affiliations

    • Pediatric Infectious Disease Clinic, University of Sassari, Sassari, Italy
  • ,
  • Paolina Olmeo, MD

      Affiliations

    • Pediatric Infectious Disease Clinic, University of Sassari, Sassari, Italy
  • ,
  • Renzo Delogu, MD

      Affiliations

    • Department of Public Health, Sassari, Italy.
  • ,
  • Silvia Ortu, PhD

      Affiliations

    • Department of Biomedical Science, University of Sassari, Sassari, Italy
  • ,
  • Leonardo Antonio Sechi, PhD

      Affiliations

    • Department of Biomedical Science, University of Sassari, Sassari, Italy
  • ,
  • Stefania Zanetti, PhD

      Affiliations

    • Department of Biomedical Science, University of Sassari, Sassari, Italy

Received 5 July 2007 ,Revised 6 November 2007 ,Accepted 5 December 2007.

References 

  1. Shingadia D, Novelli V. Diagnosis and treatment of tuberculosis in children. Lancet Infect Dis. 2003;3:624–632
  2. Pai M. Alternatives to the tuberculin skin test: interferon-gamma assays in the diagnosis of Mycobacterium tuberculosis infection. Indian J Med Microbiol. 2005;23:151–158
  3. Mori T, Sakatani M, Yamagishi F, Takashima T, Kawabe Y, Nagao K, et al. Specific detection of tuberculosis infection: an interferon-gamma based assay using new antigens. Am J Respir Crit Care Med. 2004;170:59–64
  4. Arend SM, Engelhard AC, Groot G, de Boer K, Andersen P, Ottenhoff TH, et al. Tuberculin skin testing compared with T-cell responses to Mycobacterium tuberculosis–specific and –nonspecific antigens for detection of latent infection in person with recent tuberculosis contact. Clin Diagn Lab Immunol. 2001;8:1089–1096
  5. Ardito F, Posteraro B, Sanguinetti M, Zanetti S, Fadda G. Evaluation of the BACTEC mycobacteria growth indicator tube (MGIT 960) automated system for drug susceptibility testing of Mycobacterium tuberculosis. J Clin Microbiol. 2001;39:4440–4444
  6. Ginesu F, Pirina P, Sechi LA, Molicotti P, Santoru L, Porcu L, et al. Microbiological diagnosis of tuberculosis: a comparison of old and new methods. J Chemother. 1998;10:295–300
  7. American Thoracic Society. Diagnostic standards and classification of tuberculosis in adults and children. Am J Respir Crit Care Med. 2000;161:1376–1395
  8. Sechi LA, Zanetti S, Dupre I, Aceti A, Sanguinetti M, Fadda G. Genotypic changes in DNA fingerprinting patterns of Mycobacterium tuberculosis strains from HIV-positive persons in Sardinia. AIDS. 1998;12:2084–2086
  9. Starke JR. Pediatric tuberculosis: new time for a new approach. Tuberculosis. 2003;83:208–212
  10. Mazurek GH, Jereb J, Lobue P, Iademarco MF, Metchock B, Vernon A. Division of Tuberculosis Elimination, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention (Guidelines for using the QuantiFERON-TB gold test for detecting Mycobacterium tuberculosis infection, United States). MMWR Recomm Rep. 2005;54(RR-15):49–55Erratum 54:1288

PII: S0022-3476(07)01160-2

doi: 10.1016/j.jpeds.2007.12.014

The Journal of Pediatrics
Volume 152, Issue 4 , Pages 585-586 , April 2008