The Journal of Pediatrics
Volume 152, Issue 1 , Pages 15-19 , January 2008

Prevalence, Neonatal Characteristics, and First-Year Mortality of Down Syndrome: A National Study

  • Michel E. Weijerman, ME, MD

      Affiliations

    • Department of Pediatrics and Infectious Diseases, VU University Medical Center, Amsterdam, The Netherlands
    • Corresponding Author InformationReprint requests: Michel E. Weijerman, MD, Department of Pediatrics and Infectious Diseases, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
    • ,
  • A. Marceline van Furth, PhD

      Affiliations

    • Department of Pediatrics and Infectious Diseases, VU University Medical Center, Amsterdam, The Netherlands
    • ,
  • Antonie Vonk Noordegraaf

      Affiliations

    • Department of Pediatrics and Infectious Diseases, VU University Medical Center, Amsterdam, The Netherlands
    • ,
  • Jacobus P. van Wouwe, PhD

      Affiliations

    • TNO Quality of Life, Leiden, The Netherlands.
    • ,
  • Chantal J.M. Broers, MD

      Affiliations

    • Department of Pediatrics and Infectious Diseases, VU University Medical Center, Amsterdam, The Netherlands
    • ,
  • Reinoud J.B.J. Gemke, PhD

      Affiliations

    • Department of Pediatrics and Infectious Diseases, VU University Medical Center, Amsterdam, The Netherlands

Received 27 June 2007 ,Revised 15 August 2007 ,Accepted 20 September 2007.

References 

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  8. Anthony S, Dorrepaal CA, Kateman H, van der Pal-Bruin KM. TNO Report on Congenital defects in the Netherlands 1996-2003. In: Netherlands Organisation for Applied Scientific Research, TNO, Quality of Life, Leiden, The Netherlands KvL JPB 2005. 2005;p. 1–64152
  9. Dutch Society for Obstetrics and Gynaecology and Dutch Society of Clinical Genetics. Annual Report of the Working Group on Prenatal Diagnosis and Therapy. 2003;
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  12. Dolk H, Loane M, Garne E, De Walle H, Queisser-Luft A, De Vigan C, et al. Trends and geographic inequalities in the prevalence of Down syndrome in Europe, 1980-1999. Rev Epidemiol Sante Publique. 2005;53(Special Issue 2):2S87-95
  13. Heuterman JS, de Walle HE, Poortvliet MC, Bouman K, Cornel MC. Age at postnatal diagnosis of Down syndrome in the northern Netherlands for the period 1981-2000. Community Genet. 2004;7:55–59
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  18. van Trotsenburg AS, Heymans SA, Tijssen GP, de Vijlder JM, Vulsma T. Comorbidity, hospitalization, and medication use and their influence on mental and motor development of young infants with Down syndrome. Pediatrics. 2006;118:1633–1639
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  20. Aumonier ME, Cunningham CC. Breast-feeding in infants with Down’s syndrome. Child Care Health Dev. 1983;9:247–255
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  23. Taylor B, Wadsworth J. Breast-feeding and child development at five years. Dev Med Child Neurol. 1984;26:73–80
  24. Sadetzki S, Chetrit A, Akstein E, Luxemburg O, Keinan L, Litvak I, et al. Risk factors for infant mortality in Down’s syndrome: a nationwide study. Paediatr Perinat Epidemiol. 1999;13:442–451
  25. Hayes C, Johnson Z, Thornton L, Fogarty J, Lyons R, O’Connor M, et al. Ten-year survival of Down syndrome births. Int J Epidemiol. 1997;26:822–829

 Supported by Artsen voor Kinderen.

PII: S0022-3476(07)00895-5

doi: 10.1016/j.jpeds.2007.09.045

The Journal of Pediatrics
Volume 152, Issue 1 , Pages 15-19 , January 2008

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