The Journal of Pediatrics
Volume 152, Issue 3 , Pages 378-382 , March 2008

Sensitivity of the Bacterial Meningitis Score in 889 Children with Bacterial Meningitis

  • François Dubos, MD

      Affiliations

    • From the Clinical Epidemiology Unit, Department of Pediatrics, Saint-Vincent-de-Paul Hospital, AP–HP and Paris Descartes University, Paris, France
    • Pediatric Emergency and Infectious Diseases Unit, Jeanne-de-Flandre Hospital, CHU Lille and Lille-2 University, Lille, France
    • INSERM U149, Paris, France.
    • ,
  • France De la Rocque, MD

      Affiliations

    • Groupe de Pathologie Infectieuse Pédiatrique – Association Clinique et Therapeutique Infantile du Val-de-Marne (GPIP/ACTIV Bacterial Meningitis French Surveillance Network), Saint-Maur-des-Fossés, France
    • ,
  • Corinne Levy, MD

      Affiliations

    • Groupe de Pathologie Infectieuse Pédiatrique – Association Clinique et Therapeutique Infantile du Val-de-Marne (GPIP/ACTIV Bacterial Meningitis French Surveillance Network), Saint-Maur-des-Fossés, France
    • ,
  • Edouard Bingen, MD

      Affiliations

    • Groupe de Pathologie Infectieuse Pédiatrique – Association Clinique et Therapeutique Infantile du Val-de-Marne (GPIP/ACTIV Bacterial Meningitis French Surveillance Network), Saint-Maur-des-Fossés, France
    • ,
  • Yannick Aujard, MD

      Affiliations

    • Groupe de Pathologie Infectieuse Pédiatrique – Association Clinique et Therapeutique Infantile du Val-de-Marne (GPIP/ACTIV Bacterial Meningitis French Surveillance Network), Saint-Maur-des-Fossés, France
    • ,
  • Robert Cohen, MD

      Affiliations

    • Groupe de Pathologie Infectieuse Pédiatrique – Association Clinique et Therapeutique Infantile du Val-de-Marne (GPIP/ACTIV Bacterial Meningitis French Surveillance Network), Saint-Maur-des-Fossés, France
    • ,
  • Gérard Bréart, MD

      Affiliations

    • INSERM U149, Paris, France.
    • ,
  • Bacterial Meningitis Study Group
    • ,
  • Dominique Gendrel, MD

      Affiliations

    • From the Clinical Epidemiology Unit, Department of Pediatrics, Saint-Vincent-de-Paul Hospital, AP–HP and Paris Descartes University, Paris, France
    • ,
  • Martin Chalumeau, MD, PhD

      Affiliations

    • From the Clinical Epidemiology Unit, Department of Pediatrics, Saint-Vincent-de-Paul Hospital, AP–HP and Paris Descartes University, Paris, France
    • INSERM U149, Paris, France.
    • Corresponding Author InformationReprint requests: Dr. Martin Chalumeau, Clinical Epidemiology Unit − Department of Pediatrics, Saint-Vincent-de-Paul Hospital, 82 avenue Denfert-Rochereau, 75014 Paris, France.

Received 21 March 2007 ,Revised 25 May 2007 ,Accepted 6 July 2007.

References 

  1. Nigrovic LE, Kuppermann N, Malley R. Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era. Pediatrics. 2002;110:712–719
  2. Nigrovic LE, Kuppermann N, Macias CG, Cannavino CR, Moro-Sutherland DM, Schremmer RD, et al. Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis. JAMA. 2007;297:52–60
  3. Dubos F, Lamotte B, Bibi-Triki F, Moulin F, Raymond J, Gendrel D, et al. Distinguishing between bacterial and viral meningitis in children in the emergency room: reproducibility and comparison of five clinical decision rules. Arch Dis Child. 2006;91:647–650
  4. Saez-Llorens X, McCracken GH. Bacterial meningitis in children. Lancet. 2003;361:2139–2148
  5. El Bashir H, Laundy M, Booy R. Diagnosis and treatment of bacterial meningitis. Arch Dis Child. 2003;88:615–620
  6. Tunkel H, Kaplan SL, Kaufman BA, Roos KL, Scheld WM, Whitley RJ. Practice guidelines for the management of bacterial meningitis. Clin Infect Dis. 2004;39:1267–1284
  7. Feigin RD, McCracken GH, Klein JO. Diagnosis and management of meningitis. Pediatr Infect Dis J. 1992;11:785–814
  8. Khetsuriani N, Quiroz ES, Holman RC, Anderson LJ. Viral meningitis-associated hospitalizations in the united states 1988-1999. Neuroepidemiology. 2003;22:345–352
  9. Parasuraman TV, Frenia K, Romero J. Enteroviral meningitis: cost of illness and considerations for the economic evaluation of potential therapies. Pharmacoeconomics. 2001;19:3–12
  10. Haruda FD. Meningitis: viral versus bacterial. Pediatrics. 2003;112:447–448
  11. Stiell IG, Wells GA. Methodologic standards for the development of clinical decision rules in emergency medicine. Ann Emerg Med. 1999;33:437–447
  12. McGinn TG, Guyatt GH, Wyer PC, Naylor CD, Stiell IG, Richardson WS. User’s guides to the medical literature: XXII: how to use articles about clinical decision rules: Evidence-Based Medicine Working Group. JAMA. 2000;284:79–84
  13. Pierart J, Lepage P. Value of the ‘Bacterial Meningitis Score’ (BMS) for the differential diagnosis of bacterial versus viral meningitis. Rev Med Liege. 2006;61:581–585
  14. Bingen E, Levy C, de La Rocque F, Boucherat M, Varon E, Alonso JM, et al. Bacterial meningitis in children: a French prospective study. Clin Infect Dis. 2005;41:1059–1063
  15. Bonsu BK, Harper MB. Differentiating acute bacterial meningitis from acute viral meningitis among children with cerebrospinal fluid pleocytosis: a multivariable regression model. Pediatr Infect Dis J. 2004;23:511–517
  16. Freedman SB, Marrocco A, Pirie J, Dick PT. Predictors of bacterial meningitis in the era after Haemophilus influenzae. Arch Pediatr Adolesc Med. 2001;155:1301–1306
  17. Stiell IG, Greenberg GH, McKnight RD, Nair RC, McDowell I, Reardon M, et al. Decision rules for the use of radiography in acute ankle injuries: refinement and prospective validation. JAMA. 1993;269:1127–1132
  18. Cohen R, de La Rocque F, Aujard Y, Bingen E. National surveillance of bacterial meningitis in children. Arch Pediatr. 2003;10(Suppl 1):114–115
  19. Perrocheau A, Doyle A, Bernillon P, Varon E Regional Pneumococcal Observatories, De la Rocque F, et al. Evaluation of the surveillance of paediatric pneumococcal meningitis infections in France, 2001-2002 by capture-recapture method. Bull Epidemiol Hebd. 2006;2-3:16–18
  20. Cohen R, Gaudelus J, Peixoto O. Vaccin antipneumococcique conjugué: estimation de la population cible: enquête auprès de 1739 mères. Médecine et Enfance. 2005;25:237–242
  21. Assicot M, Gendrel D, Carsin H, Raymond J, Guilbaud J, Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet. 1993;341:515–518
  22. Simon L, Gauvin F, Amre DK, Saint-Louis P, Lacroix J. Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis. Clin Infect Dis. 2004;39:206–217
  23. Korczowski B, Bijos A, Rybak A. Procalcitonin in diagnosis of purulent and aseptic meningitis in children. Pol Merkuriusz Lek. 2000;9:755–757
  24. Dubos F, Moulin F, Gajdos V, De Suremain N, Biscardi S, Lebon P, et al. Serum procalcitonin and other biologic markers to distinguish between bacterial and aseptic meningitis. J Pediatr. 2006;149:72–76
  25. Dubos F, Korczowski B, Aygun AD, Martinot A, Prat C, Galetto-Lacour A, et al. Procalcitonin to distinguish between bacterial and aseptic meningitis: a European multicenter validation study. In: Presented at: European Society of Paediatric Infectious Diseases. 24th Annual Meeting, Basel, May 3-5. 2006;32 (Abstract)
  26. Dubos F, Moulin F, Raymond J, Gendrel D, Breart G, Chalumeau M. Distinction between bacterial and aseptic meningitis in children: refinement of a clinical decision rule. Arch Pediatr. 2007;14:434–438
  27. Bottner A, Daneschnejad S, Handrick W, Schuster V, Liebert UG, Kiess W. A season of aseptic meningitis in Germany: epidemiologic, clinical and diagnostic aspects. Pediatr Infect Dis J. 2002;21:1126–1132

 Supported by the Pediatric Infectious Diseases Group of the French Pediatrics Society (GPIP), the Association Clinique et Therapeutique Infantile du Val de Marne (ACTIV), the DRC (CRC 03154) and the URC-Cochin, AP-HP, the Fonds d’Etudes et de Recherche du Corps Médical des Hôpitaux de Paris, and the Fondation Bayer Santé.

PII: S0022-3476(07)00664-6

doi: 10.1016/j.jpeds.2007.07.012

The Journal of Pediatrics
Volume 152, Issue 3 , Pages 378-382 , March 2008

Article Tools

* Image Usage & Resolution