Michael W. Konstan, MD, Wayne J. Morgan, MD, Steven M. Butler, PhD, David J. Pasta, MS, Marcia L. Craib, MS, Stefanie J. Silva, MS, Dennis C. Stokes, MD, Mary Ellen B. Wohl, MD, Jeffrey S. Wagener, MD, Warren E. Regelmann, MD, and Charles A. Johnson, MBChB, for the Scientific Advisory Group and the Investigators and Coordinators of the Epidemiologic Study of Cystic Fibrosis, Cleveland, Ohio, Tucson, Arizona, South San Francisco and San Francisco, California, Lebanon, New Hampshire, Boston, Massachusetts, Denver, Colorado, and Minneapolis, Minnesota

50 Years Ago in The Journal of Pediatrics—Obstruction to Left Atrial Outflow by a Supravalvular Stenosing Ring 139

Reginald L. Washington, MD, Denver, Colorado

Hemolytic Uremic Syndrome Associated with Invasive Pneumococcal Disease: The United Kingdom Experience 140

Aoife M. Waters, MRCPI, Larissa Kerecuk, MRCPCH, David Luk, MRCPCH, Mushfequr R. Haq, FRCPCH, Margaret M. Fitzpatrick, FRCPCH, Rodney D. Gilbert, FRCPCH, Carol Inward, FRCPCH, Caroline Jones, MRCPCH, Bruno Pichon, PhD, Christopher Reid, FRCPCH, Mary P. E. Slack, FRCPath, William Van’t Hoff, FRCPCH, Michael J. Dillon, FRCPCH, C. M. Taylor, FRCPCH, and Kjell Tullus, FRCPCH, London, Leeds, Southampton, Bristol, and Liverpool, UK

A Randomized Clinical Trial of a New Orthodontic Appliance to Improve Upper Airway Obstruction in Infants with Pierre Robin Sequence 145

Wolfgang Buchenau, MD, Michael S. Urschitz, MD, Judit Sautermeister, MD, Margit Bacher, MD, Tina Herberts, Joerg Arand, MD, and Christian F. Poets, MD, Tuebingen, Germany

Myocardial Infarction in Adolescents 150

William T. Mahle, MD, Robert M. Campbell, MD, and Jennifer Favaloro-Sabatier, MSC, Atlanta, Georgia

50 Years Ago in The Journal of Pediatrics—The Early Definitive Diagnosis of Patients with Congenital Heart Disease 154

Reginald L. Washington, MD, Denver, Colorado

Tissue Inhibitor of Metalloproteinase 2 and Coronary Artery Lesions in Kawasaki Disease 155

Kenji Furuno, MD, PhD, Hidetoshi Takada, MD, PhD, Ken Yamamoto, MD, PhD, Kazuyuki Ikeda, MD, Takuro Ohno, MD, PhD, Vahid Khajoee, MD, PhD, Yumi Mizuno, MD, PhD, and Toshiro Hara, MD, PhD, Fukuoka, Japan

Growth and Nutritional Status in Residential Center Versus Home-Living Children and Adolescents with Quadriplegic Cerebral Palsy 161

Richard C. Henderson, MD, PhD, Richard I. Grossberg, MD, Jeanine Matuszewski, BS, Nitasha Menon, BA, Julie Johnson, MD, Heidi H. Kecskemethy, RD, CSP, Lois Vogel, MS, PT, PCS, Rebecca Ravas, PT, MS, Megan Wyatt, MPT, Steven J. Bachrach, MD, and Richard D. Stevenson, MD, Chapel Hill, North Carolina, Mantua, Ohio, Sioux Falls, South Dakota, Wilmington, Delaware, Philadelphia, Pennsylvania, and Charlottesville, Virginia

Primary Immunization of Premature Infants with Gestational Age <35 Weeks: Cardiorespiratory Complications and C-Reactive Protein Responses Associated with Administration of Single and Multiple Separate Vaccines Simultaneously 167

Massroor Pourcyrous, MD, Sheldon B. Korones, MD, Kristopher L. Arheart, PhD, and Henrietta S. Bada, MD, Memphis, Tennessee, Miami, Florida, and Lexington, Kentucky

50 Years Ago in The Journal of Pediatrics—The Social Management of the Epileptic Child and His Parents 172

Paul Graham Fisher, MD, Palo Alto, California

Pre-Exposure Rabies Vaccination Using Purified Chick Embryo Cell Rabies Vaccine Intradermally is Immunogenic and Safe 173

Thavatchai Kamoltham, MD, MSc, Wirawan Thinyounyong, BSc, Phana Phongchamnaphai, MD, Phran Phraisuwan, MD, Pakamatz Khawplod, PhD, Angelika Banzhoff, MD, and Claudius Malerczyk, MD, Phetchabun, Thailand, and Marburg, Germany

50 Years Ago in The Journal of Pediatrics—Low Cerebrospinal Fluid Glucose Associated with Meningeal Neoplasia 177

Sonia Partap, MD, Palo Alto, California

Risk Factors for Development of Subclinical Hypothyroidism during Valproic Acid Therapy 178

M. A. Mikati, MD, H. Tarabay, MD, A. Khalil, MD, A. C. Rahi, MPH, D. El Banna, MPH, and S. Najjar, MD, Beirut, Lebanon

Parental Reports of Health-Related Quality Of Life in Young Children with Neurofibromatosis Type 1: Influence of Condition Specific Determinants 182

Rianne Oostenbrink, MD, PhD, Kimberly Spong, MSc, Arja de Goede-Bolder, MD, Jeanne M. Landgraf, MA, Hein Raat, MD, PhD, and Henriette A. Moll, MD, PhD, Rotterdam, The Netherlands, and Boston, Massachusetts

Aeroallergen Sensitization in Healthy Children: Racial and Socioeconomic Correlates 187

Michelle D. Stevenson, MD, MS, Stacey Sellins, MMS, Emilie Grube, BA, Kathy Schroer, BS, Jayanta Gupta, MD, Ning Wang, PhD, and Gurjit K. Khurana Hershey, MD, PhD, Akron and Cincinnati, Ohio

Specific Cognitive Deficits in Young Children with Cystinosis: Evidence for an Early Effect of the Cystinosin Gene on Neural Function 192

Doris A. Trauner, MD, Amy M. Spilkin, PhD, Jennifer Williams, and Lynne Babchuck, La Jolla, California

Clinical Consequences of Interrupting Enzyme Replacement Therapy in Children with Type 1 Gaucher Disease 197

Guillermo Drelichman, MD, Elvira Ponce, MD, MSc, Nora Basack, MD, Daniel Freigeiro, MD, Luis Aversa, MD, Elena Graciela, MD, and Regina Kohan, MD, Buenos Aires, Argentina

A Comparison of Reviewers Selected by Editors and Reviewers Suggested by Authors 202

Frederick P. Rivara, MD, MPH, Peter Cummings, MD, MPH, Sarah Ringold, MD, Abraham B. Bergman, MD, Alain Joffe, MD, MPH, and Dimitri A. Christakis, MD, MPH, Seattle, Washington, and Baltimore, Maryland

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Grand Rounds

An Unusual Cause of Pediatric Hypertension 206

Kevin Friedman, MD, Traci Wallis, MD, Kelly W. Maloney, MD, Richard J. Hendrickson, MD, Sarah Mengshol, MD, and Melissa A. Cadnapaphornchai, MD, Denver, Colorado, and Indianapolis, Indiana

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Clinical and Laboratory Observations

In Preterm Neonates, is the Risk of Developing Bronchopulmonary Dysplasia Influenced by the Failure to Protect Total Parenteral Nutrition from Exposure to Ambient Light? 213

Philippe Chessex, MD, Adele Harrison, MD, Minesh Khashu, MD, and Jean-Claude Lavoie, PhD, Vancouver, British Columbia, and Montreal, Quebec, Canada

BK Virus-Induced Tubulointerstitial Nephritis in a Child with Acute Lymphoblastic Leukemia 215

Hiroto Inaba, MD, PhD, Deborah P. Jones, MD, Lillian W. Gaber, MD, Jerry L. Shenep, MD, Sandra K. Call, PharmD, Ching-Hon Pui, MD, and Bassem I. Razzouk, MD, Memphis, Tennessee

Immunization Rates among Disabled Children in Ecuador: Unanticipated Findings 218

Nora Ellen Groce, PhD, Paola Ayora, MD, MPH, and Lawrence C. Kaplan, MD, ScM, FAAP, New Haven, Connecticut, New York, New York, and Hanover, New Hampshire

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