The Journal of Pediatrics
Volume 152, Issue 1 , Pages 96-100 , January 2008

Effect of Levo-Thyroxine Treatment on Weight and Body Mass Index in Children with Acquired Hypothyroidism

  • Jefferson P. Lomenick, MD

      Affiliations

    • Division of Pediatric Endocrinology, Lexington, KY
    • Corresponding Author InformationReprint requests: Jefferson P. Lomenick, MD, 740 South Limestone, Kentucky Clinic, J463, Lexington, KY 40536-0284.
    • ,
  • Maysa El-Sayyid, BS

      Affiliations

    • University of Kentucky College of Medicine, Lexington, KY.
    • ,
  • W. Jackson Smith, MD

      Affiliations

    • Division of Pediatric Endocrinology, Lexington, KY

Received 16 March 2007 ,Revised 2 May 2007 ,Accepted 5 June 2007.

References 

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  2. Silva JE. The thermogenic effect of thyroid hormone and its clinical implications. Ann Intern Med. 2003;139:205–213
  3. Watanakunakorn C, Hodges RE, Evans TC. Myxedema: a study of 400 cases. Arch Intern Med. 1965;116:183–190
  4. Plummer WA. Body weight in spontaneous myxedema. Trans Am Goiter Assoc. 1940;88–98
  5. Baron DN. Hypothyroidism: its aetiology and relation to hypometabolism, hypercholesterolaemia, and increase in body-weight. Lancet. 1956;271:277–281
  6. Halliburton. Report of a committee of the Clinical Society of London to investigate the subject of myxedema. Trans Clin Soc. 1888;21(suppl):47
  7. Hoogwerf BJ, Nuttall FQ. Long-term weight regulation in treated hyperthyroid and hypothyroid subjects. Am J Med. 1984;76:963–970
  8. Kyle LH, Ball MF, Doolan PD. Effect of thyroid hormone on body composition in myxedema and obesity. N Engl J Med. 1966;275:12–17
  9. Byrom FB. The nature of myxoedema. Clin Sci. 1933;1:273–285
  10. Ord WM. On myxoedema, a term proposed to be applied to an essential condition in the cretinoid affection occasionally observed in the middle-aged women. Med Chir Soc Trans. 1878;61:57–78
  11. Barlow SE, Dietz WH. Obesity evaluation and treatment: Expert Committee recommendations (The Maternal and Child Health Bureau, Health Resources and Services Administration and the Department of Health and Human Services). Pediatrics. 1998;102:e29
  12. Dietz WH, Robinson TN. Clinical practice: overweight children and adolescents. N Engl J Med. 2005;352:2100–2109
  13. O’Brien SH, Holubkov R, Reis EC. Identification, evaluation, and management of obesity in an academic primary care center. Pediatrics. 2004;114:e154–e159
  14. Pears J, Jung RT, Gunn A. Long-term weight changes in treated hyperthyroid and hypothyroid patients. Scott Med J. 1990;35:180–182
  15. Larsen PR, Davies TF, Hay ID. The thyroid gland. In:  Wilson JD,  Foster WF,  Kronenberg HM,  Larsen PR editor. Williams’ Textbook of Endocrinology. 9th ed.. Philadelphia: Saunders; 1998;p. 389–515
  16. Franklyn JA. Metabolic changes in hypothyroidism. In:  Braverman LE,  Utiger RD editor. Werner & Ingbar’s The Thyroid. 8th ed.. Philadelphia: Lippincott Williams & Wilkins; 2000;p. 833–836
  17. Fisher DA. Thyroid disorders in childhood and adolescence. In:  Sperling MA editors. Pediatric Endocrinology. 2nd ed.. Philadelphia: Saunders; 2002;p. 187–209
  18. Dallas JS, Foley TP. Hypothyroidism. In:  Lifshitz F editors. Pediatric Endocrinology. 4th ed.. New York: Marcel Dekker; 2003;p. 359–369

PII: S0022-3476(07)00564-1

doi: 10.1016/j.jpeds.2007.06.006

The Journal of Pediatrics
Volume 152, Issue 1 , Pages 96-100 , January 2008

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