The Journal of Pediatrics
Volume 151, Issue 4 , Pages 336-338 , October 2007

Rethinking Herpes Simplex Virus Infections in Children and Adolescents

  • Kathleen M. Gutierrez, MD

      Affiliations

    • Corresponding Author InformationReprint requests: Kathleen M. Gutierrez, MD, Division of Pediatric Infectious Diseases, Stanford University School of Medicine, 300 Pasteur Drive, Room G312, Stanford, CA 94305.

References 

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  2. Yoshikawa T, Hill JM, Stanberry LR, Bourne N, Kurawadwala JF, Krause PR. The characteristic site-specific reactivation phenotypes of HSV-1 and HSV-2 depend upon the latency-associated transcript region. J Exp Med. 1996;184:659–664
  3. Engelberg R, Carrell D, Krantz E, Corey L, Wald A. Natural history of genital herpes simplex virus type 1 infection. Sex Transm Dis. 2003;30:174–177
  4. Kim HN, Meier A, Huang ML, Kuntz S, Selke S, Celum C, et al. Oral herpes simplex virus type 2 reactivation in HIV-positive and -negative men. J Infect Dis. 2006;194:420–427
  5. Roberts CM, Pfister JR, Spear SJ. Increasing proportion of herpes simplex virus type 1 as a cause of genital herpes infection in college students. Sex Transm Dis. 2003;30:797–800
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  7. Lowhagen GB, Tunback P, Andersson K, Bergstrom T, Johannisson G. First episodes of genital herpes in a Swedish STD population: a study of epidemiology and transmission by the use of herpes simplex virus (HSV) typing and specific serology. Sex Transm Infect. 2000;76:179–182
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  9. Xu F, Sternberg MR, Kottiri BJ, McQuillan GM, Lee FK, Nahmias AJ, et al. Trends in herpes simplex virus type 1 and type 2 seroprevalence in the United States. JAMA. 2006;296:964–973
  10. Fleming DT, McQuillan GM, Johnson RE, Nahmias AJ, Aral SO, Lee FK, et al. Herpes simplex virus type 2 in the United States, 1976 to 1994. N Engl J Med. 1997;337:1105–1111
  11. Becker TM, Magder L, Harrison HR, Stewart JA, Humphrey DD, Hauler J, et al. The epidemiology of infection with the human herpesviruses in Navajo children. Am J Epidemiol. 1988;127:1071–1078
  12. Pebody RG, Andrews N, Brown D, Gopal R, De Melker H, Francois G, et al. The seroepidemiology of herpes simplex virus type 1 and 2 in Europe. Sex Transm Infect. 2004;80:185–191
  13. Wald A, Link K. Risk of human immunodeficiency virus infection in herpes simplex virus type 2-seropositive persons: a meta-analysis. J Infect Dis. 2002;185:45–52
  14. Reynolds SJ, Risbud AR, Shepherd ME, Zenilman JM, Brookmeyer RS, Paranjape RS, et al. Recent herpes simplex virus type 2 infection and the risk of human immunodeficiency virus type 1 acquisition in India. J Infect Dis. 2003;187:1513–1521
  15. Brown EL, Gardella C, Malm G, Prober CG, Forsgren M, Krantz EM, et al. Effect of maternal herpes simplex virus (HSV) serostatus and HSV type on risk of neonatal herpes. Acta Obstet Gynecol Scand. 2007;86:523–529
  16. Rouse BT, Kaistha SD. A tale of 2 alpha-herpesviruses: lessons for vaccinologists. Clin Infect Dis. 2006;42:810–817
  17. Stanberry LR, Spruance SL, Cunningham AL, Bernstein DI, Mindel A, Sacks S, et al. Glycoprotein-D-adjuvant vaccine to prevent genital herpes. N Engl J Med. 2002;347:1652–1661

PII: S0022-3476(07)00556-2

doi: 10.1016/j.jpeds.2007.05.052

The Journal of Pediatrics
Volume 151, Issue 4 , Pages 336-338 , October 2007

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