Table of Contents

Article Outline

• Notes from the Association of Medical School Pediatric Department Chairs, Inc
• Editorials
• Medical Progress
• Original Articles
• Grand Rounds
• Clinical and Laboratory Observations
• Insights
• Letters
• Reader Services

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Notes from the Association of Medical School Pediatric Department Chairs, Inc 

Pediatrics and Evidence-Based Medicine Revisited 325

Robert M. Jacobson, MD, Rochester, Minnesota

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Editorials 

Postnatal Steroids for Bronchopulmonary Dysplasia: Where Are We Now? 327

Kristi L. Watterberg, MD, Albuquerque, New Mexico

Is EGF the Holy Grail for NEC? 329

Michael Caplan, MD, Evanston, Illinois

The Systemic Effects of Short Sleep Period 331

Joseph Crisalli, MD, and Raouf S. Amin, MD, Cincinnati, Ohio

Childhood Cancer Cures: The Ongoing Consequences of Successful Treatments 332

Sharon E. Oberfield, MD, New York, New York

B Cell Depletion: On the Rise 335

Claas H. Hinze, MD, and Alexei A. Grom, MD, Cincinnati, Ohio

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Medical Progress 

Treatment with Rituximab in Benign and Malignant Hematologic Disorders in Children 338

Lisa B. Giulino, MD, James B. Bussel, MD, Ellis J. Neufeld, MD, PhD, and the Pediatric and Platelet Immunology Committees of the TMH Clinical Trial Network, New York, New York, and Boston, Massachusetts

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Original Articles 

Follow-up Study of a Randomized Controlled Trial of Postnatal Dexamethasone Therapy in Very-Low-Birth Weight Infants: Effects on Pulmonary Outcomes at Age 8 to 11 Years

Patricia A. Nixon, PhD, Lisa K. Washburn, MD, Michael S. Schechter, MD, MPH, and T. Michael O’Shea, MD, MPH, Winston-Salem, North Carolina, and Atlanta, Georgia

Neonatal Hydrocortisone Treatment: Neurodevelopmental Outcome and MRI at School Age in Preterm-born Children 351

Karin J. Rademaker, MD, PhD, Cuno S.P.M. Uiterwaal, MD, PhD, Floris Groenendaal, MD, PhD, Monica M.A.T. Uniken Venema, MA, PhD, Frank van Bel, MD, PhD, Frederik J. Beek, MD, PhD, Ingrid C. van Haastert, PPT, MA, Diederick E. Grobbee, MD, PhD, and Linda S. de Vries, MD, PhD, Utrecht, The Netherlands

Ontogeny of Salivary Epidermal Growth Factor and Necrotizing Enterocolitis 358

Barbara B. Warner, MD, Ann Ladd Ryan, MD, Kimberly Seeger, MD, Anthony C. Leonard, PhD, Christopher R. Erwin, PhD, and Brad W. Warner, MD, Cincinnati, Ohio

Association between Inadequate Sleep and Insulin Resistance in Obese Children 364

Janna Flint, MD, Sanjeev V. Kothare, MD, Mamoon Zihlif, MD, Elizabeth Suarez, MD, Ruth Adams, CRNP, Agustin Legido, MD, and Francesco De Luca, MD, Philadelphia, Pennsylvania

Decreased Adult Height in Survivors of Childhood Acute Lymphoblastic Leukemia: A Report from the Childhood Cancer Survivor Study 370

Eric J. Chow, MD, MPH, Debra L. Friedman, MD, MS, Yutaka Yasui, PhD, John A. Whitton, MS, Marilyn Stovall, PhD, Leslie L. Robison, PhD, and Charles A. Sklar, MD, Seattle, Washington, Edmonton, Alberta, Canada, Houston, Texas, Memphis, Tennessee, and New York, New York

Clinical Effects and Safety of Rituximab for Treatment of Refractory Pediatric Autoimmune Diseases 376

Moussa El-Hallak, MD, Bryce A. Binstadt, MD, PhD, Alan M. Leichtner, MD, Carolyn M. Bennett, MD, Ellis J. Neufeld, MD, PhD, Robert C. Fuhlbrigge, MD, PhD, David Zurakowski, PhD, and Robert P. Sundel, MD, Boston, Massachusetts

50 Years Ago in The Journal of Pediatrics—Neonatal Hepatitis in Siblings 382

Veena L. Venkat, MD, Cincinnati, Ohio

Fitness is a Stronger Predictor of Fasting Insulin Levels than Fatness in Overweight Male Middle-School Children 383

David B. Allen, MD, Blaise A. Nemeth, MD, R. Randall Clark, MS, Susan E. Peterson, MS, Jens Eickhoff, PhD, and Aaron L. Carrel, MD, Madison, Wisconsin

Relationship of Physical Activity, Fitness, and Fatness with Clustered Metabolic Risk in Children and Adolescents: The European Youth Heart Study 388

Nico S. Rizzo, MSc, Jonatan R. Ruiz, BSc, Anita Hurtig-Wennlöf, PhD, Francisco B. Ortega, BSc, and Michael Sjöström, MD, PhD, Huddinge and Örebro, Sweden, and Granada, Spain

Six-Minute Walk Test in Children and Adolescents 395

Ralf Geiger, MD, Alexander Strasak, MD, Benedikt Treml, MD, Klaus Gasser, MD, Axel Kleinsasser, PhD, Victoria Fischer, MD, Harald Geiger, MD, Alexander Loeckinger, PhD, and Joerg I. Stein, PhD, Innsbruck and Dornbirn, Austria

50 Years Ago in The Journal of Pediatrics—Agenesis of the Corpus Callosum: Report of Eight Cases in Infancy 399

Sonia Partap, MD, Palo Alto, California

Impaired Endothelial Function in Healthy African-American Adolescents Compared with Caucasians 400

Mary M. Duck, BS, and Robert P. Hoffman, MD, Columbus, Ohio

Cardiac Manifestations in Oxidative Phosphorylation Disorders of Childhood 407

J. Yaplito-Lee, MD, R. Weintraub, MBBS, K. Jamsen, BSc(Math), C. W. Chow, MBBS, D. R. Thorburn, PhD, and A. Boneh, MD, PhD, Melbourne, Australia

Evaluation of Discharge Management in the Prediction of Hyperbilirubinemia: The Jerusalem Experience 412

Michael Kaplan, MB, ChB, Ruben Bromiker, MD, Michael S. Schimmel, MD, Nurit Algur, MSc, and Cathy Hammerman, MD, Jerusalem and Be’er Sheva, Israel

50 Years Ago in The Journal of Pediatrics—Pediatric Use of Dioctyl Sodium Sulfosuccinate 417

Dean R.Focht, MD, Honolulu, Hawaii

Pre-ductal and Post-ductal O₂ Saturation in Healthy Term Neonates after Birth 418

Gonzalo Mariani, MD, Pablo Brener Dik, MD, Analía Ezquer, MD, Adolfo Aguirre, MD, Mirta Lucía Esteban, MD, Cecilia Perez, MD, Silvia Fernandez Jonusas, MD, and Carlos Fustiñana, MD, Buenos Aires, Argentina

Continuing Anemia Prevention Strategies Are Needed Throughout Early Childhood in Low-income Preschool Children 422

Sarah E. Cusick, PhD, Zuguo Mei, MD, MPH, and Mary E. Cogswell, DrPH, RN, Atlanta, Georgia

50 Years Ago in The Journal of Pediatrics—Premature Infant Mortality 428

K.S. Joseph, MD, PhD, and Michael S. Kramer, MD, Halifax, Nova Scotia, and Montreal, Quebec, Canada

Evaluation of the Utility of Radiography in Acute Bronchiolitis 429

Suzanne Schuh, MD, Amina Lalani, MD, Upton Allen, MBBS, David Manson, MD, Paul Babyn, MD, Derek Stephens, MSc, Shannon MacPhee, MD, Matthew Mokanski, RN, Svetlana Khaikin, RN, and Paul Dick, MDCM, MSc, Toronto, Ontario, Canada

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Grand Rounds 

Ethical and Legal Implications of Genetic Testing in Androgen Insensitivity Syndrome 434

Jonathan S. Berg, MD, PhD, Shannon L. French, MD, Laurence B. McCullough, PhD, Soledad Kleppe, MD, Vernon R. Sutton, MD, Sheila K. Gunn, MD, and Lefkothea P. Karaviti, MD, PhD, Houston, Texas

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Clinical and Laboratory Observations 

Hearing Loss in Biotinidase Deficiency: Genotype-Phenotype Correlation 439

Hatice Serap Kalkano lu Sivri, MD, Gülsüm Aydan Genç, PhD, Ayþegül Tokatlý, MD, Ali Dursun, MD, PhD, Turgay Coþkun, MD, Halil Ýbrahim Aydýn, MD, Levent Sennaro lu, MD, Erol Belgin, PhD, Kevin Jensen, BS, and Barry Wolf, MD, PhD, Ankara, Turkey, Farmington, Connecticut, and Detroit, Michigan

Pyruvate Kinase (PK) Deficiency in Newborns: The Pitfalls of Diagnosis 443

Serge Pissard, MD, PhD, Mariane de Montalembert, MD, Dora Bachir, MD, Isabelle Max-Audit, MD, PhD, Michel Goossens, MD, Henri Wajcman, MD, PhD, and Brigitte Bader-Meunier, MD, Créteil and Paris, France

Hospitalizations with Primary versus Secondary Discharge Diagnoses of Asthma: Implications for Pediatric Asthma Surveillance 446

David G. Bundy, MD, MPH, Chapel Hill, North Carolina

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Insights 

Esophageal Stenosis Due to Vascular Ring 450

Kazushi Yasuda, MD, Norihisa Koyama, MD, Hiroomi Murayama, MD, and Takashi Watanabe, MD, Aichi, Japan

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Letters 

The following section is available in the online version of The Journal.

Definition of Metabolic Syndrome e36

Elizabeth Goodman, MD, Stephen R. Daniels, MD, PhD, and Lawrence M. Dolan, MD, Boston, Massachusetts, Denver, Colorado, and Cincinnati, Ohio

Reply e36

Carolyn Chi, MD, Darrell Wilson, MD, and Thomas Robinson, MD, MPH, Stanford, California

External Validation of a Scoring System to Predict Resistance to Intravenous Immunoglobulin e37

Tohru Kobayashi, MD, Yoshinari Inoue, MD, Kazushi Tamura, MD, Akihiro Morikawa, MD, and Tomio Kobayashi, MD, Gunma, Japan

Reply e38

Hiromi Muta, MD, Kimiyasu Egami, MD, Toyojiro Matsuishi, MD, and Masahiro Ishii, MD, Kurume and Sagamihara, Japan

Finding a Direction for Pediatric Assent e38

Suzanne Manning, RN, JD, MA, Toronto, Ontario, Canada

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Reader Services 

Information for Readers 9A

Announcements 10A

Recertifications Available at www.jpeds.com e39

Guide for Authors Available at www.jpeds.com