B-cell depletion in pediatrics
Article Outline
B-cell depletion is being used in a wide range of disorders. El-Hallak et al at Harvard Medical School have reviewed their experience with treatment of refractory autoimmune disorders in this issue of The Journal. Although only 10 patients are reported, this is the largest pediatric experience reported for children with autoimmune diseases.
The article is discussed in some detail by Claas Hinze and Alexei Grom from Cincinnati Children’s Hospital Medical Center, Division of Rheumatology.
page 376 (article)page 335 (editorial)
PII: S0022-3476(07)00183-7
doi:10.1016/j.jpeds.2007.02.043
© 2007 Mosby, Inc. All rights reserved.
Refers to article:
- Clinical Effects and Safety of Rituximab for Treatment of Refractory Pediatric Autoimmune Diseases
- B Cell Depletion: On the Rise

