The Journal of Pediatrics
Volume 150, Issue 6 , Pages 640-644.e1, June 2007

Prevalence of Hypertension and Pre-Hypertension among Adolescents

  • Karen L. McNiece, MD

      Affiliations

    • Department of Pediatrics, Division of Pediatric Nephrology and Hypertension, University of Texas-Houston, School of Medicine, Houston, Texas
    • Corresponding Author InformationReprint requests: Karen L. McNiece, MD, Division of Pediatric Nephrology and Hypertension, University of Texas - Houston, School of Medicine, 6431 Fannin St, MSB 3.124, Houston, TX 77057.
  • ,
  • Timothy S. Poffenbarger

      Affiliations

    • Department of Pediatrics, Division of Pediatric Nephrology and Hypertension, University of Texas-Houston, School of Medicine, Houston, Texas
  • ,
  • Jennifer L. Turner

      Affiliations

    • Department of Pediatrics, Division of Pediatric Nephrology and Hypertension, University of Texas-Houston, School of Medicine, Houston, Texas
  • ,
  • Kathy D. Franco, BSN

      Affiliations

    • Department of Pediatrics, Division of Pediatric Nephrology and Hypertension, University of Texas-Houston, School of Medicine, Houston, Texas
  • ,
  • Jonathan M. Sorof, MD

      Affiliations

    • AstraZeneca Pharmaceuticals, Houston, Texas.
  • ,
  • Ronald J. Portman, MD

      Affiliations

    • Department of Pediatrics, Division of Pediatric Nephrology and Hypertension, University of Texas-Houston, School of Medicine, Houston, Texas

Received 27 July 2006; received in revised form 22 November 2006; accepted 31 January 2007.

Objective

To determine the prevalence of hypertension and pre-hypertension on the basis of the 2004 National High Blood Pressure Education Program Working Group guidelines in an adolescent school-screening population.

Study design

Cross-sectional assessment of blood pressure (BP) in 6790 adolescents (11-17 years) in Houston schools was conducted from 2003 to 2005. Initial measurements included height, weight, and 4 oscillometric BP readings. Repeat measurements were obtained on 2 subsequent occasions in students with persistently elevated BP. Final prevalence was adjusted for loss to follow-up and logistic regression used to assess risk factors.

Results

BP distribution at initial screen was 81.1% normal, 9.5% pre-hypertension, and 9.4% hypertension (8.4% Stage 1; 1% Stage 2). Prevalence after 3 screenings was 81.1% normal, 15.7% pre-hypertension, and 3.2% hypertension (2.6% Stage 1; 0.6% Stage 2). Hypertension and pre-hypertension increased with increasing body mass index. Sex, race, and classification as either at-risk for overweight or overweight were independently associated with pre-hypertension. Only classification as overweight was associated with hypertension.

Conclusions

Application of new classification guidelines for adolescents with elevated BP reveals ∼20% are at risk for hypertension. Further research determining the significance of each BP category and refining definitions to account for BP variability is warranted.

Abbreviations: BMI, Body mass index, BP, Blood pressure, CI, Confidence interval, DBP, Diastolic blood pressure, OR, Odds ratio, SBP, Systolic blood pressure

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 Supported by NIH Ruth L. Kirschstein National Research Service Individual Fellowship Award no. F32 HL079813.

PII: S0022-3476(07)00124-2

doi:10.1016/j.jpeds.2007.01.052

The Journal of Pediatrics
Volume 150, Issue 6 , Pages 640-644.e1, June 2007