The Journal of Pediatrics
Volume 150, Issue 1 , Pages 3-5 , January 2007

Extreme Pediatric Obesity: Weighing the Health Dangers

  • Stavra A. Xanthakos, MD

      Affiliations

    • Assistant Professor of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Medical Director of the Comprehensive Weight Management Center, Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH
  • ,
  • Thomas H. Inge, MD, PhD

      Affiliations

    • Associate Professor of Surgery and Pediatrics, Division of Pediatric and Thoracic Surgery, Surgical Director of the Comprehensive Weight Management Program, Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH
    • Corresponding Author InformationReprint requests: Dr Thomas Harris Inge, Cincinnati Children’s Hospital Medical Center, Division of Pediatric and Thoracic Surgery, ML 2023, 3333 Burnet Ave, Cincinnati, OH 45229.

References 

  1. Sturm R. Increases in clinically severe obesity in the United States, 1986-2000. Arch Intern Med. 2003;163:2146–2148
  2. Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA. 2006;295:1549–1555
  3. Ogden CL, Flegal KM, Carroll MD, Johnson CL. Prevalence and trends in overweight among US children and adolescents, 1999-2000. JAMA. 2002;288:1728–1732
  4. Hedley AA, Ogden CL, Johnson CL, Carroll MD, Curtin LR, Flegal KM. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA. 2004;291:2847–2850
  5. Freedman DS, Mei Z, Srinivasan SR, Berenson GS, Dietz WH. Cardiovascular risk factors and excess adiposity among overweight children and adolescents: The Bogalusa Heart Study. J Pediatr. 2006;150:12
  6. Freedman DS, Dietz WH, Srinivasan SR, Berenson GS. The relation of overweight to cardiovascular risk factors among children and adolescents: The Bogalusa Heart Study. Pediatrics. 1999;103:1175–1182
  7. Adams KF, Schatzkin A, Harris TB, Kipnis V, Mouw T, Ballard-Barbash R, et al. Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med. 2006;355:763–778
  8. Pontiroli AE, Galli L. Duration of obesity is a risk factor for non-insulin-dependent diabetes mellitus, not for arterial hypertension or for hyperlipidaemia. Acta Diabetol. 1998;35:130–136
  9. Must A, Jacques PF, Dallal GE, Bajema CJ, Dietz WH. Long-term morbidity and mortality of overweight adolescents: a follow-up of the Harvard Growth Study of 1922 to 1935. N Engl J Med. 1992;327:1350–1355
  10. DiPietro L, Mossberg HO, Stunkard AJ. A 40-year history of overweight children in Stockholm: life-time overweight, morbidity, and mortality. Int J Obes Relat Metab Disord. 1994;18:585–590
  11. Gunnell DJ, Frankel SJ, Nanchahal K, Peters TJ, Davey Smith G. Childhood obesity and adult cardiovascular mortality: a 57-y follow-up study based on the Boyd Orr cohort. Am J Clin Nutr. 1998;67:1111–1118
  12. Freedman DS, Khan LK, Dietz WH, Srinivasan SR, Berenson GS. Relationship of childhood obesity to coronary heart disease risk factors in adulthood: The Bogalusa Heart Study. Pediatrics. 2001;108:712–718
  13. van Dam RM, Willett WC, Manson JE, Hu FB. The relationship between overweight in adolescence and premature death in women. Ann Intern Med. 2006;145:91–97
  14. Barlow SE. Bariatric surgery in adolescents: for treatment failures or health care system failures. Pediatrics. 2004;114:252–253
  15. Yanovski JA, Yanovski SZ. Treatment of pediatric and adolescent obesity. JAMA. 2003;289:1851–1853
  16. Epstein LH, Valoski A, Wing RR, McCurley T. Ten-year follow-up of behavioral, family-based treatment for obese children. JAMA. 1990;264:2519–2523
  17. Levine MD, Ringham RM, Kalarchian MA, Wisniewski L, Marcus MD. Is family-based behavioral weight control appropriate for severe pediatric obesity. Int J Eat Disord. 2001;30:318–328
  18. Kirk S, Zeller M, Claytor R, Santangelo M, Khoury PR, Daniels SR. The relationship of health outcomes to improvement in BMI in children and adolescents. Obes Res. 2005;13:876–882
  19. Berkowitz RI, Wadden TA, Tershakovec AM, Cronquist JL. Behavior therapy and sibutramine for the treatment of adolescent obesity: a randomized controlled trial. JAMA. 2003;289:1805–1812
  20. Chanoine JP, Hampl S, Jensen C, Boldrin M, Hauptman J. Effect of orlistat on weight and body composition in obese adolescents: a randomized controlled trial. JAMA. 2005;293:2873–2883
  21. Zeller M, Kirk S, Claytor R, Khoury P, Grieme J, Santangelo M, et al. Predictors of attrition from a pediatric weight management program. J Pediatr. 2004;144:466–470
  22. Hansen EN, Torquati A, Abumrad NN. Results of bariatric surgery. Annu Rev Nutr. 2006;26:481–511
  23. Sjostrom L, Lindroos AK, Peltonen M, Torgerson J, Bouchard C, Carlsson B, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351:2683–2693
  24. Maggard MA, Shugarman LR, Suttorp M, Maglione M, Sugerman HJ, Livingston EH, et al. Meta-analysis: surgical treatment of obesity. Ann Intern Med. 2005;142:547–559
  25. Lawson ML, Kirk S, Mitchell T, Chen MK, Loux TJ, Daniels SR, et al. One-year outcomes of Roux-en-Y gastric bypass for morbidly obese adolescents: a multicenter study from the Pediatric Bariatric Study Group. J Pediatr Surg. 2006;41:137–143discussion, 43
  26. Strauss RS, Bradley LJ, Brolin RE. Gastric bypass surgery in adolescents with morbid obesity. J Pediatr. 2001;138:499–504
  27. Inge TH, Krebs NF, Garcia VF, Skelton JA, Guice KS, Strauss RS, et al. Bariatric surgery for severely overweight adolescents: concerns and recommendations. Pediatrics. 2004;114:217–223
  28. Apovian CM, Baker C, Ludwig DS, Hoppin AG, Hsu G, Lenders C, et al. Best practice guidelines in pediatric/adolescent weight loss surgery. Obes Res. 2005;13:274–282
  29. Garcia VF, DeMaria EJ. Adolescent bariatric surgery: treatment delayed, treatment denied, a crisis invited. Obes Surg. 2006;16:1–4
  30. Sugerman HJ, Sugerman EL, DeMaria EJ, Kellum JM, Kennedy C, Mowery Y, et al. Bariatric surgery for severely obese adolescents. J Gastrointest Surg. 2003;7:102–107discussion, 7-8
  31. Fielding GA, Duncombe JE. Laparoscopic adjustable gastric banding in severely obese adolescents. Surg Obes Relat Dis. 2005;1:399–405discussion, 7
  32. Zeller MH, Roehrig HR, Modi AC, Daniels SR, Inge TH. Health-related quality of life and depressive symptoms in adolescents with extreme obesity presenting for bariatric surgery. Pediatrics. 2006;117:1155–1161
  33. Tsai W, Inge T, Burd R. Adolescent bariatric surgery: recent national trends in utilization and in hospital outcomes. Arch Pediatr Adolesc Med. 2006;In press
  34. Adolescent Bariatrics: Assessing Health Benefits and Risks (1U01DK072493-01A1) Primary Investigator: Inge, Thomas. http://crisp.cit.nih.gov. Accessed December 7, 2006.

PII: S0022-3476(06)01107-3

doi: 10.1016/j.jpeds.2006.11.040

The Journal of Pediatrics
Volume 150, Issue 1 , Pages 3-5 , January 2007