The Journal of Pediatrics
Volume 149, Issue 5 , Page A1, November 2006

Children treated with valproic acid have evidence of oxidative stress

Article Outline

 

Michoulas et al from the University of British Columbia report increased urinary levels of 15-F2t-isoprostane compared to control groups. These results suggest that reactive oxygen species may have a role in the hepatotoxicity of valproic acid.

 page 692

PII: S0022-3476(06)00932-2

doi:10.1016/j.jpeds.2006.10.002

The Journal of Pediatrics
Volume 149, Issue 5 , Page A1, November 2006